Results 71 to 80 of about 6,285 (179)

Automated Solid-Phase Radiofluorination Using Polymer-Supported Phosphazenes

Molecules, 2013
The polymer supported phosphazene bases PS-P2tBu and the novel PS-P2PEG allowed for efficient extraction of [18F]F− from proton irradiated [18O]H2O and subsequent radiofluorination of a broad range of substrates directly on the resin.
Bente Mathiessen, Fedor Zhuravlev
doaj   +1 more source

Ion‐Pairing and Counterion Effects in Contemporary Photochemistry

Angewandte Chemie Novit, Volume 2, Issue 2, June 2026.
Ion‐pairing and counterion effects have emerged as fundamental yet underexplored determinants of photochemical behavior. Far from inert, counterions, and Coulombic interactions modulate excited‐state dynamics, quenching efficiencies, emission, and catalytic pathways.
Matthias Schmitz, Christoph Kerzig
wiley   +1 more source

Optimization of the radiosynthesis of [18F] FESP

, 2012
Optimization of the radiosynthesis of [18F] FESPOptimization of the radiosynthesis of [18F] FESPkatedra jaderné ...
Seifert Daniel
core  

Adventures in radiosynthesis of clinical grade [⁶⁸Ga]Ga-DOTA-Siglec-9

, 2018
[68Ga]Ga-DOTA-Siglec-9 is the first vascular adhesion protein-1 targeting radiopharmaceutical for positron emission tomography imaging of inflammation, and here we present its long-awaited clinical grade radiosynthesis.
Anne Roivainen, Helena Virtanen, Xiang-Guo Li, Tapio Viljanen, Heidi Liljenbäck, Pauliina Luoto, Sirpa Jalkanen, Meeri Käkelä, Juhani Knuuti   +8 more
core   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, Volume 4, Issue 3, Page 219-245, June 2026.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source

Radiosynthesis and Biological Evaluation of [18F]R91150, a Selective 5-HT2A Receptor Antagonist for PET-Imaging

, 2021
Serotonergic 5-HT2A receptors in cortical and forebrain regions are an important substrate for the neuromodulatory actions of serotonin in the brain. They have been implicated in the etiology of many neuropsychiatric disorders and serve as a target for ...
Neumaier, Bernd, Hegger, Julian, Willmann, Michael., Neumaier, Bernd., Ermert, Johannes, Willmann, Michael, Hegger, Julian., Ermert, Johannes., Johannes Ermert, Michael Willmann, Julian Hegger, Bernd Neumaier   +11 more
core   +1 more source

Efficient one-pot radiosynthesis of the 11C-labeled aquaporin-4 inhibitor TGN-020

EJNMMI Radiopharmacy and Chemistry
Background [11C]TGN-020 has been developed as a positron emission tomography (PET) tracer for imaging aquaporin-4 (AQP4) in the brain and used in clinical studies.
Kazunori Kawamura, Katsushi Kumata, Tomoteru Yamasaki, Masanao Ogawa, Yusuke Kurihara, Nobuki Nengaki, Yukimi Nakamura, Maiko Ono, Yuhei Takado, Hironaka Igarashi, Ming-Rong Zhang   +10 more
doaj   +1 more source

Fully automated radiosynthesis of [18F]LBT999 on TRACERlab FXFN and AllinOne modules, a PET radiopharmaceutical for imaging the dopamine transporter in human brain

EJNMMI Radiopharmacy and Chemistry, 2020
Background Fluorine labelled 8-((E)-4-fluoro-but-2-enyl)-3β-p-tolyl-8-aza-bicyclo[3.2.1]octane-2β-carboxylic acid methyl ester ([18F]LBT999) is a selective radioligand for the in vivo neuroimaging and quantification of the dopamine transporter by ...
Christine Vala, Céline Mothes, Gabrielle Chicheri, Pauline Magadur, Gilles Viot, Jean-Bernard Deloye, Serge Maia, Yann Bouvet, Anne-Claire Dupont, Nicolas Arlicot, Denis Guilloteau, Patrick Emond, Johnny Vercouillie   +12 more
doaj   +1 more source

Development of a Novel 18F‐Labeled Radioligand for Imaging Translocator Protein With Positron Emission Tomography

iRADIOLOGY, Volume 4, Issue 3, Page 261-272, June 2026.
Translocator protein 18 kDa (TSPO) is a well‐established biomarker of neuroinflammation and is implicated in the pathophysiology of various neurodegenerative diseases. This study presents [18F]TSPO‐1118 ([18F]3) as a promising positron emission tomography (PET) radioligand for imaging TSPO with high affinity, robust brain uptake, and specificity in ...
Jian Rong, Chunyu Zhao, Xin Zhou, Jiahui Chen, Yabiao Gao, Zhendong Song, Yinlong Li, Zijing Li, Steven H. Liang   +8 more
wiley   +1 more source

Robust and Facile Automated Radiosynthesis of [18F]FSPG on the GE FASTlab [PDF]

, 2020
Purpose: (S)-4-(3-18F-Fluoropropyl)-ʟ-Glutamic Acid ([18F]FSPG) is a radiolabeled non-natural amino acid that is used for positron emission tomography (PET) imaging of the glutamate/cystine antiporter, system xC-, whose expression is upregulated in many ...
Timothy, Witney, Richard, Edwards, Hannah, Greenwood   +2 more
core   +1 more source