Results 61 to 70 of about 208,218 (280)

Inhibition of choroidal osteoma progression using bisphosphonate and RANKL-inhibitory treatment

American Journal of Ophthalmology Case Reports
Purpose: To describe the use of anti-osteoclastic medications (i.e., bisphosphonates and receptor activator of nuclear factor kappa beta (RANK) ligand inhibitors) in treating choroidal osteoma.
Mélanie Hébert, Kelly Babic, Edward C. Hsiao, Armin Afshar, Nisha Acharya, John A. Gonzales   +5 more
doaj   +1 more source

Clinical, instrumental, serological and histological findings suggest that hemophilia B may be less severe than hemophilia A

Haematologica, 2016
Recent evidence suggests that patients with severe hemophilia B may have a less severe disease compared to severe hemophilia A. To investigate clinical, radiological, laboratory and histological differences in the arthropathy of severe hemophilia A and ...
Daniela Melchiorre, Silvia Linari, Mirko Manetti, Eloisa Romano, Francesco Sofi, Marco Matucci-Cerinic, Christian Carulli, Massimo Innocenti, Lidia Ibba-Manneschi, Giancarlo Castaman   +9 more
doaj   +1 more source

Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. [PDF]

, 2010
IntroductionThe interaction between the immune and skeletal systems is evidenced by the bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we describe a new mechanism by which the immune cytokine IL-17A directly affects
Adamopoulos, Iannis E, Blumenschein, Wendy, Bowman, Edward P, Chao, Cheng-Chi, Geissler, Richard, Iwakura, Yoichiro, Laface, Drake, McClanahan, Terrill   +7 more
core   +1 more source

The impact of high density receptor clusters on VEGF signaling

, 2013
Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates ...
Chen, Ye, Edwards, Jeremy S., Halász, Ádám M., Short, Christopher   +3 more
core   +2 more sources

Sum Rules for Multi-Photon Spectroscopy of Ions in Finite Symmetry [PDF]

, 1998
Models describing one- and two-photon transitions for ions in crystalline environments are unified and extended to the case of parity-allowed and parity- forbidden p-photon transitions.
Au-chin Tang, B. R. Judd, B. R. Judd, G. S. Ofelt, J. D. Axe Jr., J. S. Griffith, J. S. Griffith, J. Sztucki, J. Sztucki, L. Smentek-Mielczarek, M. C. Downer, M. Daoud, M. Daoud, M. F. Reid, M. Flato, M. Inoue, M. Kibler, M. Kibler, M. Kibler, M. Kibler, M. Kibler, M. R. Kibler, P. A. Apanasevich, R. C. Leavitt, S. K. Gayen, S. Sugano, T. R. Bader, W. Low   +27 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Osteoporose e erosões osseas focais na artrite reumatóide: da patogênese ao tratamento Osteoporosis and focal erosive bone lesions in rheumatoid arthritis: pathogeny and treatment

Revista Brasileira de Reumatologia, 2004
As erosões ósseas focais e a osteoporose constituem manifestações características da artrite reumatóide e são importantes no desenvolvimento de deformidades e incapacidade funcional relacionadas com a doença.
Ivânio Alves Pereira, Rosa Maria Rodrigues Pereira   +1 more
doaj   +1 more source

Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda, Atsushi Yamashita, Misa Otsu, Masanori Koide, Yuko Nakamichi, Yoko Sekita‐Hatakeyama, Kinta Hatakeyama, Taro Funamoto, Etsuo Chosa, Yujiro Asada, Nobuyuki Udagawa, Johji Kato, Kazuo Kitamura   +12 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Receptor Activator of Nuclear Factor-Kappa Ligand and Osteoprotegerin Expressions on Hyperglycemic Wistar Rats (Rattus Novergicus) During Orthodontic Tooth Movement

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To investigate the differences of receptor activator of nuclear factor-κB ligand (RANKL) and Osteoprotegerin (OPG) expressions between normoglycemic and hyperglycemic Wistar rats (Rattus Novergicus) during Orthodontic Tooth Movement (OTM ...
Alida Alida, Ervina Restiwulan Winoto, Ida Bagus Narmada   +2 more
doaj