Results 81 to 90 of about 133,829 (277)
Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda +12 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]
, 2013 Peer ...
Thompson, K. +3 more
core +2 more sources
Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022 Objective: To investigate the differences of receptor activator of nuclear factor-κB ligand (RANKL) and Osteoprotegerin (OPG) expressions between normoglycemic and hyperglycemic Wistar rats (Rattus Novergicus) during Orthodontic Tooth Movement (OTM ...
Alida Alida +2 more
doaj
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Effect of Lovastatin on Serum Osteoprotegerin Level in Type 2 Diabetic Nephropathy
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2012 BACKGROUND AND OBJECTIVE: Osteoprotegerin (OPG), a glycoprotein is a member of the tumor necrotizing factor alpha receptor super-family. By considering the possible role of OPG in cardiovascular disease (CVD), higher incidence of CVD in patients with ...
N Nezami, +5 more
doaj
Severe, Symptomatic Hypocalcemia due to Denosumab Administration: Treatment and Clinical Course
Case Reports in Nephrology and Dialysis, 2019 Denosumab is a receptor activator of nuclear factor kappa-B (RANK) ligand inhibitor used in the treatment of osteoporosis. Blockade of RANK ligand prevents osteoclastic resorption of bone, but in doing so impairs the parathyroid hormone (PTH)-driven ...
Jarred Strickling, Michael J. Wilkowski
doaj +1 more source
RANKL/RANK/osteoprotegerin system as novel therapeutic target in the treatment of primary bone tumors and osteolytic metastases [PDF]
Archive of Oncology, 2004 Primary bone tumors and cancers that metastasize to bone require osteoclastic activity to release tumor-supportive growth factors from bone tissue.
Anđelković Zlatibor +4 more
doaj +1 more source
FUSING SIMILARITY RANKINGS IN LIGAND-BASED VIRTUAL SCREENING [PDF]
Computational and Structural Biotechnology Journal, 2013 Data fusion is the name given to a range of methods for combining multiple sources of evidence. This mini-review summarizes the use of one such class of methods for combining the rankings obtained when similarity searching is used for ligand-based virtual screening.
openaire +5 more sources