Results 31 to 40 of about 88,529 (348)

Brucella and Osteoarticular Cell Activation: Partners in Crime [PDF]

, 2017
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis.
Adamopoulos, Adarichev, Al-Eissa, Aydin, Azuma, Bartok, Behera, Bivi, Bonewald, Burrage, Buzgan, Cenci, Chen, Civitelli, Colmenero, Delpino, Delpino, Delpino, D’Amelio, D’Amelio, El-Jawhari, Farkas, Fuller, Garcia Samartino, Geiger, Giambartolomei, Giambartolomei, Gilmore, Goenka, Goenka, Golding, Gotuzzo, Grundt, Haynes, Horowitz, Ibero, Ikeda, Inman, Karner, Kasim, Kawai, Kitazawa, Kobayashi, Kollet, Kong, Kotake, Lacey, Lampiasi, Lerner, Madkour, Madkour, Magnani, Merkel, Milner, Mori, Nair, Nakayamada, Pappas, Pappas, Pesce Viglietti, Press, Prideaux, Rajapakse, Rajashekara, Rodan, Roggia, Sato, Scian, Scian, Scian, Scian, Shaalan, Skyberg, Soder, Song, Streuli, Takayanagi, Takayanagi, Takayanagi, Tanaka, Teitelbaum, Thomson, Tokoyoda, Turan, Viau, Visnjic, Wallach, Wei, Yasuda, Young, Young, Zhan, Zhan, Zhan, Zhao, Zwerdling   +95 more
core   +1 more source

Osteopetrosis rescue upon RANKL administration to Rankl−/− mice: A new therapy for human RANKL-dependent ARO [PDF]

Journal of Bone and Mineral Research, 2012
Abstract In the last decades the molecular basis of monogenic diseases has been largely unraveled, although their treatment has often remained unsatisfactory. Autosomal recessive osteopetrosis (ARO) belongs to the small group of genetic diseases that are usually treated with hematopoietic stem cell transplantation (HSCT).
LO IACONO N, BLAIR HC, POLIANI, Pietro Luigi, MARRELLA V, FICARA F, CASSANI B, FACCHETTI, Fabio, FONTANA, Elena, GUERRINI MM, TRAGGIAI E, SCHENA F, PAULIS M, MANTERO S, INFORZATO A, VALAPERTA S, PANGRAZIO A, CRISAFULLI L, MAINA V, KOSTENUIK P, VEZZONI P, VILLA A, SOBACCHI C.   +21 more
openaire   +2 more sources

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts [PDF]

, 2017
Acknowledgements We sincerely thank the patients and family members who participated in this study. We would also like to thank Stefan Esher, Umeå University, for help with genealogy, and Anna Westerlund for excellent technical assistance.
Ameur, Adam, Coxon, Fraser P., Dahl, Niklas, Hallmans, Göran, Helfrich, Miep H., Henning, Petra, Kellgren, Therese G., Klar, Joakim, Lerner, Ulf H., Lönnerholm, Torsten, McDermott, Emma, Rydén, Patrik, Sandström, Per-Erik, Stattin, Eva-Lena, Stecksen-Blicks, Christina, Wikström, Johan   +15 more
core   +1 more source

RANK–RANKL signalling in cancer [PDF]

Bioscience Reports, 2016
Oncogenic events combined with a favourable environment are the two main factors in the oncological process. The tumour microenvironment is composed of a complex, interconnected network of protagonists, including soluble factors such as cytokines, extracellular matrix components, interacting with fibroblasts, endothelial cells, immune cells and various
Heymann, D., Renema, N., Navet, B., Heymann, M.F., Lezot, F.   +4 more
openaire   +3 more sources

Modeling of the kinetics of vitamin D$_3$ in osteoblastic cells

Mathematical Biosciences and Engineering, 2012
A one-dimensional model for the transport of vitamin D$_3$ in anosteoblast cell is proposed, from its entry through the membraneto its activation of RANKL synthesis in the nucleus.
Robert P. Gilbert, Philippe Guyenne, Ying Liu   +2 more
doaj   +1 more source

The Effects of Acute Exercise on RANKL/RANK/OPG Pathway and Bone Metabolic Markers in Healthy College Female [PDF]

운동과학, 2018
PURPOSE The purpose of this study was to examine the effects of acute exercise with difference Intensitis on RANKL/RANK/OPG pathway and bone metabolic markers in healthy college female. METHODS Ten healthy college females (aged 21.5±1.84 years; VO2max 37.
Ji-Yeon Kim, Hyo-Jin Kim, Dong-Ho Park, Yun-A Shin, Seok-Ki Min, Chang-Sun Kim   +5 more
doaj   +1 more source

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]

, 2019
Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G., Bellido, Teresita, Delgado-Calle, Jesus, Galmarini, Carlos Maria, Kurihara, Noriyoshi, Miyagawa, Kazuaki, Nelson, Jessica, Roodman, G. David   +7 more
core   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS, Douni E., MARCHETTI, Luigi, SABBIETI, Maria Giovanna   +3 more
core   +1 more source

Serum RANKL, osteoprotegerin (OPG), and RANKL/OPG ratio in nephrotic children [PDF]

Pediatric Nephrology, 2010
Receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) play key roles in the pathogenesis of glucocorticoid-induced osteoporosis (GIO). The aim of our study was to determine whether the cumulative glucocorticoid dose (CGCS) in children with idiopathic nephrotic syndrome (INS) has any effect on the concentration of serum RANKL and OPG and ...
Wasilewska, Anna, Rybi-Szuminska, Agnieszka, Zoch-Zwierz, Walentyna   +2 more
openaire   +2 more sources

EFFECT OF INFLIXIMAB ON PARAMETERS OF REMODELING OF ARTERIAL BLOODSTREAM, RANKL AND OSTEOPROTEGERIN LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2014
Objective. To study the effect of infliximab (INF) on serum levels of RANKL and osteoprotegerin (OPG), as well as on structural and functional properties of the vascular wall in patients with rheumatoid arthritis (RA).Material and Methods.
Larisa Aleksandrovna Knyazeva, N S Meshcherina   +1 more
doaj   +1 more source