Results 31 to 40 of about 81,008 (204)

Assessment of Salivary Levels of the RANKL and RANK in Patients with Healthy Gingiva on Reduced Periodontium Versus Periodontitis: An Analytical Cross-Sectional Study

Dental Hypotheses, 2023
Introduction: We aimed to compare the changes in the two salivary biomarkers, RANKL and RANK, among patients with healthy gingiva on reduced periodontium versus generalized periodontitis stages II and III.
Shurooq Abdulkareem Muhssin, Hadeel Mazin Akram   +1 more
doaj   +1 more source

Osteopetrosis rescue upon RANKL administration to Rankl−/− mice: A new therapy for human RANKL-dependent ARO [PDF]

Journal of Bone and Mineral Research, 2012
Abstract In the last decades the molecular basis of monogenic diseases has been largely unraveled, although their treatment has often remained unsatisfactory. Autosomal recessive osteopetrosis (ARO) belongs to the small group of genetic diseases that are usually treated with hematopoietic stem cell transplantation (HSCT).
LO IACONO N, BLAIR HC, POLIANI, Pietro Luigi, MARRELLA V, FICARA F, CASSANI B, FACCHETTI, Fabio, FONTANA, Elena, GUERRINI MM, TRAGGIAI E, SCHENA F, PAULIS M, MANTERO S, INFORZATO A, VALAPERTA S, PANGRAZIO A, CRISAFULLI L, MAINA V, KOSTENUIK P, VEZZONI P, VILLA A, SOBACCHI C.   +21 more
openaire   +2 more sources

Brucella and Osteoarticular Cell Activation: Partners in Crime [PDF]

, 2017
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis.
Adamopoulos, Adarichev, Al-Eissa, Aydin, Azuma, Bartok, Behera, Bivi, Bonewald, Burrage, Buzgan, Cenci, Chen, Civitelli, Colmenero, Delpino, Delpino, Delpino, D’Amelio, D’Amelio, El-Jawhari, Farkas, Fuller, Garcia Samartino, Geiger, Giambartolomei, Giambartolomei, Gilmore, Goenka, Goenka, Golding, Gotuzzo, Grundt, Haynes, Horowitz, Ibero, Ikeda, Inman, Karner, Kasim, Kawai, Kitazawa, Kobayashi, Kollet, Kong, Kotake, Lacey, Lampiasi, Lerner, Madkour, Madkour, Magnani, Merkel, Milner, Mori, Nair, Nakayamada, Pappas, Pappas, Pesce Viglietti, Press, Prideaux, Rajapakse, Rajashekara, Rodan, Roggia, Sato, Scian, Scian, Scian, Scian, Shaalan, Skyberg, Soder, Song, Streuli, Takayanagi, Takayanagi, Takayanagi, Tanaka, Teitelbaum, Thomson, Tokoyoda, Turan, Viau, Visnjic, Wallach, Wei, Yasuda, Young, Young, Zhan, Zhan, Zhan, Zhao, Zwerdling   +95 more
core   +1 more source

RANK–RANKL signalling in cancer [PDF]

Bioscience Reports, 2016
Oncogenic events combined with a favourable environment are the two main factors in the oncological process. The tumour microenvironment is composed of a complex, interconnected network of protagonists, including soluble factors such as cytokines, extracellular matrix components, interacting with fibroblasts, endothelial cells, immune cells and various
Heymann, D., Renema, N., Navet, B., Heymann, M.F., Lezot, F.   +4 more
openaire   +3 more sources

Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity [PDF]

, 2017
Extracellular signal-regulated protein kinase 5 (ERK5) has been implicated during development and carcinogenesis. Nkx3.1-mediated Cre expression is a useful strategy to genetically manipulate the mouse prostate. While grossly normal at birth, we observed
Ahmad, Imran, Blyth, Karen, Charlesworth, Gemma, Daroszewska, Anna, Ford, Catriona, King, Ayala, Leung, Hing Y., Loveridge, Carolyn J., Mui, Ernest J., Prior, Amanda, Rose, Lorraine, Salji, Mark, Sansom, Owen, Tan, Ee Hong, van ’t Hof, Rob J., Welsh, Michelle   +15 more
core   +2 more sources

Serum fetuin-A and RANKL levels in patients with early stage breast cancer [PDF]

Journal of Medical Biochemistry, 2023
Background: Breast cancer (BC) is the primary cause of mortality due to cancer in females around the world. Fetuin-A is known to increase metastases over signals and peroxisomes related with growing. Receptor activator of nuclear factor-kB ligand (RANKL)
Afsar Cigdem Usul, Aral Hale, Can Orçun, Can Trabulus Didem, Karacetin Didem, Ali Nazlı Mehmet, Umar Gursu Rıza, Karabulut Senem   +7 more
doaj  

The unbearable lightness of bone marrow homeostasis [PDF]

, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS, Douni E., MARCHETTI, Luigi, SABBIETI, Maria Giovanna   +3 more
core   +1 more source

ПАТОФИЗИОЛОГИЧЕСКАЯ РОЛЬ ОСТЕОПРОТЕГЕРИНА ПРИ АТЕРОСКЛЕРОЗЕ И САХАРНОМ ДИАБЕТЕ

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2022
Сахарный диабет справедливо называют неинфекционной эпидемией 21 века. Вместе с тем сердечно-сосудистые заболевания по-прежнему лидируют среди причин смертности в мире.
A. R. Obukhovich, N. N. Iaskevich
doaj   +1 more source

Serum RANKL, osteoprotegerin (OPG), and RANKL/OPG ratio in nephrotic children [PDF]

Pediatric Nephrology, 2010
Receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) play key roles in the pathogenesis of glucocorticoid-induced osteoporosis (GIO). The aim of our study was to determine whether the cumulative glucocorticoid dose (CGCS) in children with idiopathic nephrotic syndrome (INS) has any effect on the concentration of serum RANKL and OPG and ...
Wasilewska, Anna, Rybi-Szuminska, Agnieszka, Zoch-Zwierz, Walentyna   +2 more
openaire   +2 more sources

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]

, 2019
Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G., Bellido, Teresita, Delgado-Calle, Jesus, Galmarini, Carlos Maria, Kurihara, Noriyoshi, Miyagawa, Kazuaki, Nelson, Jessica, Roodman, G. David   +7 more
core   +1 more source