Results 31 to 40 of about 105,143 (344)

Inhibition of RANK signaling as a potential immunotherapy in breast cancer

OncoImmunology, 2021
RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment.
C Gómez-Aleza, E González-Suárez
doaj   +1 more source

A novel RANKL‐targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species

Clinical and Translational Medicine, 2021
Background and purpose Osteoporosis is characterized by excessive bone resorption due to enhanced osteoclast activation. Stimulation of nuclear factor of activated T cells 1 (NFATc1) and accumulation of reactive oxygen species (ROS) are important ...
Guo-Ju Hong, Zhenqiu Chen, Xiaorui Han, Lin Zhou, Feng-Xiang Pang, Rishana Wu, Yingshan Shen, Xiaoming He, Zhi-Nan Hong, Zi-Qi Li, W. He, Qiushi Wei   +11 more
semanticscholar   +1 more source

M CELLS ARE THE IMPORTANT POST IN THE INITIATION OF IMMUNE RESPONSE IN INTESTINE

Инфекция и иммунитет, 2018
Microfold cells (M cells) are specialized intestinal epithelial cells that initiate mucosal immune responses. These unique phagocytic epithelial cells are specialized for the transfer of a broad range of particulate antigens and microorganisms across the
A. S. Bykov, A. V. Karaulov, D. A. Tsomartova, N. L. Kartashkina, V. L. Goriachkina, S. L. Kuznetsov, D. A. Stonogina, Ye. V. Chereshneva   +7 more
doaj   +1 more source

Osteoclast activity in osteoporosis mandibular bone based on RANKL and osteoprotegerin ratio. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Osteoporosis occurs not only in the lumbar bone, femur, and radius but also occurs in the mandibular bone. Therefore, osteoporosis is a disease that required attention from the dentists.
Mefina Kuntjoro, Nike Hendrijantini, Fedik Abdul Rantam, Guang Hong, Sherman Salim, Muhammad Dimas Aditya Ari   +5 more
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The Roadmap of RANKL/RANK Pathway in Cancer

Cells, 2021
The receptor activator of the nuclear factor-κB ligand (RANKL)/RANK signaling pathway was identified in the late 1990s and is the key mediator of bone remodeling.
S. Casimiro, G. Vilhais, I. Gomes, L. Costa   +3 more
semanticscholar   +1 more source

Serum fetuin-A and RANKL levels in patients with early stage breast cancer [PDF]

Journal of Medical Biochemistry, 2023
Background: Breast cancer (BC) is the primary cause of mortality due to cancer in females around the world. Fetuin-A is known to increase metastases over signals and peroxisomes related with growing. Receptor activator of nuclear factor-kB ligand (RANKL)
Afsar Cigdem Usul, Aral Hale, Can Orçun, Can Trabulus Didem, Karacetin Didem, Ali Nazlı Mehmet, Umar Gursu Rıza, Karabulut Senem   +7 more
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Effect of Low-magnitude, High-frequency Vibration on Osteocytes in the Regulation of Osteoclasts [PDF]

, 2010
Osteocytes are well evidenced to be the major mechanosensor in bone, responsible for sending signals to the effector cells (osteoblasts and osteoclasts) that carry out bone formation and resorption. Consistent with this hypothesis, it has been shown that
Al-Dujaili, Saja, Guenther, Axel, Lau, Esther, Liu, Dawei, Wang, Liyun, You, Lidan   +5 more
core   +2 more sources

Identification of marker proteins in preterm and term birth: Relationship of rankl and HSP70 in the cord blood

Medicine Science, 2022
The goal of this research was to investigate at the expression profiles of heat shock protein 70 (HSP70) and receptor activator of nuclear factor-kappa B ligand (RANKL) in term and preterm infants.
Baris Uzunok, Selcuk Gurel
doaj   +1 more source

Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]

, 2013
Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
core   +1 more source

Nanotechnology-Boosted Biomaterials for Osteoarthritis Treatment: Current Status and Future Perspectives

International Journal of Nanomedicine, 2023
Lin Liu, Haifeng Tang, Yanjun Wang Department of Emergency, Honghui Hospital of Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of ChinaCorrespondence: Yanjun Wang; Haifeng Tang, Department of Emergency, Honghui Hospital of Xi’an Jiaotong ...
Liu L, Tang H, Wang Y
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