Results 31 to 40 of about 2,150 (202)

Novel RNA viruses in oysters revealed by virome

open access: yesiMeta, Volume 1, Issue 4, December 2022., 2022
Eighteen novel RNA viruses were found in Crassostrea hongkongensis. Phylogenic analysis shows evidence of recombination between major genes of viruses. Picobirnaviruses are ubiquitous and abundant in oysters.
Peng Zhu   +8 more
wiley   +1 more source

Development of a multiplex Loop-Mediated Isothermal Amplification (LAMP) assay for on-site diagnosis of SARS CoV-2.

open access: yesPLoS ONE, 2021
A newly identified coronavirus, designated as severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), has spread rapidly from its epicenter in China to more than 150 countries across six continents.
Woong Sik Jang   +10 more
doaj   +1 more source

Controlling Size and Surface Chemistry of Cationic Nanogels by Inverse Microemulsion ATRP

open access: yesMacromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
Cationic nanogels are prepared by atom transfer radical polymerization (ATRP) under inverse microemulsion conditions of a hydrophilic inimer that prevents monomer diffusion and hence limits droplets’ growth during polymerization. The surface functionality of the nanogels is modulated by the application of hydrophobic reactive surfactants or grafting ...
Antonina Simakova   +3 more
wiley   +1 more source

RdRp inhibitors and COVID-19: Is molnupiravir a good option?

open access: yesBiomedicine & Pharmacotherapy, 2022
Rapid changes in the viral genome allow viruses to evade threats posed by the host immune response or antiviral drugs, and can lead to viral persistence in the host cells. RNA-dependent RNA polymerase (RdRp) is an essential enzyme in RNA viruses, which is involved in RNA synthesis through the formation of phosphodiester bonds.
Hashemian, Seyed Mohammad Reza   +4 more
openaire   +2 more sources

Polyacrylic Acid Copolymers as Adhesion‐Adapted Model Materials for Cleaning Tests

open access: yesMacromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
Acrylic acid (AA) copolymers adhere physically to metallic surfaces and are used for production of layers which shall mimic real filmic contamination layers for cleaning tests. To further adjust the polymers to the reference contaminations the polarity of the copolymers is varied not only by the percentage of carboxy groups but also by additional ...
Susanne Höhne   +6 more
wiley   +1 more source

Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay

open access: yesFrontiers in Immunology, 2022
SARS-CoV-2 (severe acute respiratory syndrome coronavirus‐2), a member of the coronavirus family, appeared in 2019 and has caused the largest global public health and economic emergency in recent history, affecting almost all sectors of society. SARS-CoV-
Xiaoming Bai   +11 more
doaj   +1 more source

Importance of Zika Virus NS5 Protein for Viral Replication

open access: yesPathogens, 2019
Zika virus is the latest addition to an ever-growing list of arboviruses that are causing outbreaks with serious consequences. A few mild cases were recorded between 1960 and 1980 until the first major outbreak in 2007 on Yap Island. This was followed by
Hesham Elshahawi   +2 more
doaj   +1 more source

Cu(0)-RDRP of styrene: balancing initiator efficiency and dispersity [PDF]

open access: yesPolymer Chemistry, 2018
The optimisation of all components within Cu(0)-wire mediated polymerisation of styrene is illustrated yielding well-defined polystyrene with enhanced initiator efficiency and dispersity at higher molecular weights.
Richard Whitfield   +3 more
openaire   +4 more sources

Molecular Evolutionary Analyses of the RNA-Dependent RNA Polymerase (RdRp) Region and VP1 Gene in Human Norovirus Genotypes GII.P6-GII.6 and GII.P7-GII.6

open access: yesViruses, 2023
To understand the evolution of GII.P6-GII.6 and GII.P7-GII.6 strains, the prevalent human norovirus genotypes, we analysed both the RdRp region and VP1 gene in globally collected strains using authentic bioinformatics technologies.
Tomoko Takahashi   +19 more
doaj   +1 more source

The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp

open access: yesSaudi Journal of Biological Sciences, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp) is a well-characterized therapeutic target which is a key player driving the viral replication and transcription machinery. The recent elucidation of the experimental structure of SARS-CoV-2 RdRp enzyme complexed with triphosphate form of Remdesivir (RTP ...
Gurung, Arun Bahadur   +4 more
openaire   +3 more sources

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