Results 61 to 70 of about 814,412 (288)

Evaluation of Rapid Antigen Test Results and Real-time Reverse Transcription Polymerase Chain Reaction for the Laboratory Diagnosis of SARS-CoV-2

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2023
Introduction: Real-time reverse transcription-polymerase chain reaction (RT-PCR) is the gold standard method for the diagnosis of Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) infection.
Yeliz TANRIVERDİ ÇAYCI, Zeliha SEYFİ, Kübra HACIEMİNOĞLU ÜLKER, Demet GÜR VURAL, Kemal BİLGİN, Hızır Ufuk AKDEMİR, Esra AKYÜZ ÖZKAN, Asuman BİRİNCİ   +7 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The development and application of the two real-time RT-PCR assays to detect the pathogen of HFMD. [PDF]

PLoS ONE, 2013
Large-scale Hand, Foot, and Mouth Disease (HFMD) outbreaks have frequently occurred in China since 2008, affecting more than one million children and causing several hundred children deaths every year. The pathogens of HFMD are mainly human enteroviruses
Aili Cui, Changping Xu, Xiaojuan Tan, Yan Zhang, Zhen Zhu, Naiying Mao, Yiyu Lu, Wenbo Xu   +7 more
doaj   +1 more source

The impact of co-infection of influenza A virus on the severity of Middle East Respiratory Syndrome Coronavirus [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altwaijri, Talal A., Alzahrani, Nojoom A., Memish, Ziad A.   +4 more
core   +1 more source

Primers for real-time quantitative RT-PCR.

, 2022
Primers were designed using Primer-BLAST or according to previous reports[24,62]. 24. Sengiku, A.; Ueda, M.; Kono, J.; Sano, T.; Nishikawa, N.; Kunisue, S.; Tsujihana, K.; Liou, L.S.; Kanematsu, A.; Shimba, S., et al. Circadian coordination of ATP release in the urothelium via connexin43 hemichannels. Sci Rep 2018, 8, 1996, doi:10.1038/s41598-018-20379-
openaire   +1 more source

Real-Time RT-PCR for the Detection of Lyssavirus Species [PDF]

Journal of Veterinary Medicine, 2014
The causative agents of rabies are single-stranded, negative-sense RNA viruses in the genus Lyssavirus of Rhabdoviridae, consisting of twelve classified and three as yet unclassified species including classical rabies virus (RABV). Highly neurotropic RABV causes rapidly progressive encephalomyelitis with nearly invariable fatal outcome.
Deubelbeiss, Andrea, Zahno, Marie-Luise, Zanoni, Manuela, Brügger, Dorothy, Zanoni, Reto Giacomo   +4 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Clinical Investigations. Comparison of Directigen Flu A+B with Real Time PCR in the Diagnosis of Influenza / Сравнение Иммунохроматографического Метода (Directigen Flu A+B) И Теста RT-PCR При Инфекциях Гриппа

Folia Medica, 2015
Для ранней диагностики и лечения пациентов с гриппом нужны высокочувствительные диагностические тесты, применение которых не требует сложного лабораторного оборудования, а продолжительность проведения и читки реакции не превышает 15 минут.
Bosevska Golubinka, Panovski Nikola, Janceska Elizabeta, Mikik Vladimir, Topuzovska Irena Kondova, Milenkovik Zvonko   +5 more
doaj   +1 more source

A Rapid and High-Sensitive Real-Time Reverse Transcription-Polymerase Chain Reaction Assay Used for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2

Nano Biomedicine and Engineering, 2020
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a public health emergency of international concern.
Xiaomin Chen, Yan Xu, Jing Tian, Xueling Li, Hui Liang, Ang Gao, Zexi Liu, Dicheng Yang, Qi Shen, Daxiang Cui   +9 more
doaj   +1 more source

Q-Gene: processing quantitative real-time RT–PCR data [PDF]

Bioinformatics, 2003
Abstract Summary: Q-Gene is an application for the processing of quantitative real-time RT–PCR data. It offers the user the possibility to freely choose between two principally different procedures to calculate normalized gene expressions as either means of Normalized Expressions or Mean Normalized Expressions.
openaire   +2 more sources