Results 41 to 50 of about 21,361,330 (197)

Design of glycosyltransferase UGT for thermostability and efficient biocatalytic synthesis of rebaudioside A

Acta Crystallographica Section A: Foundations and Advances, 2023
Diterpene glycosyltransferases UGT76G1 from Stevia rebaudiana Bertoni is a key enzyme in the targeted biosynthesis of noncaloric sweeteners with high-intensity sweetness, rebaudioside A. Enzymatic synthesis of rebaudioside A(RebA) from Stevioside(ST) can
Kwang-Hyun Park, Chandana S. Talwar, Young-Hoon Lee, Ju-Eun Kang, S. I. Nurheibah, Seong-Ryeong Go, Eui-Jeon Woo   +6 more
semanticscholar   +1 more source

Enhancing the thermostability and activity of glycosyltransferase UGT76G1 via computational design

Communications Chemistry, 2023
The diterpene glycosyltransferase UGT76G1, derived from Stevia rebaudiana, plays a pivotal role in the biosynthesis of rebaudioside A, a natural sugar substitute.
Seong-Ryeong Go, Su-Jin Lee, Woo-Chan Ahn, Kwang-Hyun Park, Eui-Jeon Woo   +4 more
doaj   +1 more source

The effect of methyl jasmonate on growth, stevioside and rebaudioside A production in Stevia rebaudiana shoot culture using mist bioreactor

IOP Conference Series: Earth and Environment, 2023
Steviol glycosides (SG) from Stevia rebaudiana have been used as natural sweeteners to substitute sucrose. SG production naturally needs large biomass. Therefore, it requires large area of cultivation.
A. Rahmawati, A. R. Saksyasamita, V. Emmanuel, Iriawati, K. Lambangsari, R. Esyanti, R. Othman, A. Faizal, H. Nugrahapraja   +8 more
semanticscholar   +1 more source

Safety of the proposed amendment of the specifications for enzymatically produced steviol glycosides (E 960c): Rebaudioside D produced via enzymatic bioconversion of purified stevia leaf extract

EFSA Journal, 2022
The EFSA Panel on Food Additives and Flavourings (FAF Panel) provides a scientific opinion on the safety of a proposed amendment of the specifications of enzymatically produced steviol glycosides (E 960c) with respect to the inclusion of rebaudioside D ...
EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings), Maged Younes, Gabriele Aquilina, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Rainer Gürtler, Ursula Gundert‐Remy, Trine Husøy, Melania Manco, Wim Mennes, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, José Manuel Barat Baviera, Gisela Degen, Lieve Herman, Jean‐Charles Leblanc, Detlef Wölfle, Jaime Aguilera, Alessandra Giarola, Camilla Smeraldi, Giorgia Vianello, Laurence Castle   +26 more
doaj   +1 more source

Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial

European journal of drug metabolism and pharmacokinetics, 2022
Rebaudioside A, a steviol glycoside, is deglycosylated by intestinal microflora prior to the absorption of steviol and conjugation to steviol glucuronide.
C. Simoens, Koenraad Philippaert, Caroline Wuyts, S. Goscinny, E. Van Hoeck, J. Van Loco, J. Billen, J. D. de Hoon, Els Ampe, R. Vangoitsenhoven, A. Mertens, R. Vennekens, B. Van der Schueren   +12 more
semanticscholar   +1 more source

Rebaudioside A Enhances Resistance to Oxidative Stress and Extends Lifespan and Healthspan in Caenorhabditis elegans

Antioxidants, 2021
Non-nutritive sweeteners are widely used in food and medicines to reduce energy content without compromising flavor. Herein, we report that Rebaudioside A (Reb A), a natural, non-nutritive sweetener, can extend both the lifespan and healthspan of C ...
Pan Li, Zehua Wang, S. Lam, G. Shui
semanticscholar   +1 more source

Photosynthetic performance and stevioside concentration are improved by the arbuscular mycorrhizal symbiosis in Stevia rebaudiana under different phosphate concentrations [PDF]

PeerJ, 2020
In plants, phosphorus (P) uptake occurs via arbuscular mycorrhizal (AM) symbiosis and through plant roots. The phosphate concentration is known to affect colonization by AM fungi, and the effect depends on the plant species.
Luis G. Sarmiento-López, Melina López-Meyer, Gabriela Sepúlveda-Jiménez, Luis Cárdenas, Mario Rodríguez-Monroy   +4 more
doaj   +2 more sources

De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts

Nature Communications, 2022
AbstractHigh-sugar diet causes health problems, many of which can be addressed with the use of sugar substitutes. Rubusoside and rebaudiosides are interesting molecules, considered the next generation of sugar substitutes due to their low-calorie, superior sweetness and organoleptic properties.
Yameng Xu, Xinglong Wang, Chenyang Zhang, Xuan Zhou, Xianhao Xu, Luyao Han, Xueqin Lv, Yanfeng Liu, Song Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu   +13 more
openaire   +4 more sources

Co-immobilized recombinant glycosyltransferases efficiently convert rebaudioside A to M in cascade

RSC Advances, 2021
Rebaudioside M (Reb M), as a natural and healthy Stevia sweetener, is produced by two glycosyltransferases that catalyze the serial glycosylation of Rebaudioside A (Reb A) and Rebaudioside D (Reb D) in cascade.
Zhenyang Wang, Wenbin Liu, W. Liu, Yuanyuan Ma, Yatong Li, Baoqin Wang, Xiaozhen Wei, Zhiming Liu, Hao Song   +8 more
semanticscholar   +1 more source

Influence of Tapered‐End and Round‐End Bristle Designs on the Abrasive Enamel Wear Using Toothpastes With High Discrepancies in Abrasiveness

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose The aim of this in vitro study was to investigate the influence of bristle end design of toothbrushes and the relative enamel abrasivity (REA) of used toothpaste on the resulting abrasive enamel wear. Materials and Methods A total of 160 bovine enamel samples were allocated into eight groups (n = 20) and surface topography was recorded
Michelle S. Stübi, Moritz Tanner, Blend Hamza, Leonardo Svellenti, Thomas Attin, Florian J. Wegehaupt   +5 more
wiley   +1 more source