Results 161 to 170 of about 6,320 (210)

C3a Mediates Endothelial Barrier Disruption in Brain-Derived, but Not Retinal, Human Endothelial Cells. [PDF]

Int J Mol Sci
Wolf HN, Guempelein L, Schikora J, Pauly D.   +3 more
europepmc   +1 more source

The Interaction of Neutrophil Extracellular Traps and Complement in Intracerebral Hemorrhage. [PDF]

Cell Mol Neurobiol
Shang Y, Kuang B, Zheng J, Du Y, Shang T, Luo B, Sun Y, Zheng L, Zhang B, Liu L, Zou W.   +10 more
europepmc   +1 more source

Association of Carboxypeptidase B2 Gene Polymorphisms With Graft Loss in Kidney Transplantation. [PDF]

Transplant Direct
Poppelaars F, Eskandari SK, Damman J, Frazer-Abel A, Holers VM, Dixon BP, Daha MR, Sanders JF, Seelen MA, Faria B, Gaya da Costa M, Thurman JM.   +11 more
europepmc   +1 more source

Non-canonical extracellular complement pathways and the complosome paradigm in cancer: a scoping review. [PDF]

Front Immunol
de Freitas Oliveira-Tore C, de Moraes AG, Plácido HMBS, Signorini NMDL, Fontana PD, da Piedade Batista Godoy T, Boldt ABW, de Messias I.   +7 more
europepmc   +1 more source

Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors

Mishra S, Yadav MK, Dalal A, Ganguly M, Yadav R, Sawada K, Tiwari D, Roy N, Banerjee N, Fung JN, Marallag J, Cui CS, Li XX, Lee JD, Dsouza CA, Saha S, Sarma P, Rawat G, Zhu H, Khant HA, Clark RJ, Sano FK, Banerjee R, Woodruff TM, Nureki O, Gati C, Shukla AK.   +26 more
europepmc   +1 more source

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The chemotactic receptor for human C5a anaphylatoxin

Nature, 1991
Host defence and inflammatory responses are controlled and amplified by receptor-mediated events often initiated by a chemotactic factor that directs the approach of phagocytic cells. Complement receptors CR1 and CR3 are responsible for the phagocytic and adhesive properties of neutrophils, whereas the C5a receptor mediates the pro-inflammatory and ...
N P, Gerard, C, Gerard
openaire   +2 more sources

Distribution of Rat C5a Anaphylatoxin Receptor

Microbiology and Immunology, 2002
AbstractThe anaphylatoxin, complement 5a (C5a), plays a key role in mediating various inflammatory reactions following complement activation. Several investigators have reported that C5a receptor (C5aR) is expressed in non‐myeloid cells under certain conditions or in different cell lines.
Hiroyasu, Akatsu, Masayoshi, Abe, Takashi, Miwa, Hisashi, Tateyama, Seiji, Maeda, Noriko, Okada, Kiyohide, Kojima, Hidechika, Okada   +7 more
openaire   +2 more sources

Modeling Molecular Mechanisms of Binding of the Anaphylatoxin C5a to the C5a Receptor

Biochemistry, 2008
This study presents the 3D model of the complex between the anaphylatoxin C5a and its specific receptor, C5aR. This is the first 3D model of a G-protein-coupled receptor (GPCR) complex with a peptide ligand deduced by a molecular modeling procedure analyzing various conformational possibilities of the extracellular loops and the N-terminal segment of ...
Gregory V, Nikiforovich, Garland R, Marshall, Thomas J, Baranski   +2 more
openaire   +2 more sources