Results 61 to 70 of about 174,002 (143)

Angiotensin Type 2 Receptor in Resistance Arteries of Type 2 Diabetic Hypertensive Patients [PDF]

Hypertension, 2007
The role of angiotensin type 2 receptor (AT 2 R) on vascular responses to angiotensin II in humans remains unclear. In this study we explored whether AT 2 R is expressed and functionally active on peripheral resistance arteries of hypertensive diabetic ...
SAVOIA, Carmine, R. M. Touyz, VOLPE, Massimo, E. L. Schiffrin   +3 more
openaire   +3 more sources

The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor

Frontiers in Bioscience, 2009
Angiotensin II (AngII) interacts with two receptor subtypes, AT1 and AT2, belonging to the seven transmembrane receptor superfamily. Pharmacological investigations initially suggested that AT2 receptors antagonize AT1 effects. Data from AT2 receptor transgenic and knock-out mice have not been entirely consistent with this interpretation.
Porrello, Enzo R., Delbridge, Lea M. D., Thomas, Walter G.   +2 more
openaire   +5 more sources

DAMAGE OF RENAL FUNCTION AND DYNAMICS OF DYSLIPIDEMIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH INSUFFICIENT GLYCEMIC COMPENSATION UNDER CONDITION OF CORRECTION OF HYPERTENSION WITH ANGIOTENSIN II RECEPTOR ANTAGONISTS

Український Журнал Нефрології та Діалізу, 2014
Damage of renal function and dynamics of dyslipidemia in patients with type 2 diabetes mellitus with insufficient glycemic compensation under condition of correction of hypertension with angiotensin II receptor antagonists   Introduction.
N.O. Pertseva
doaj   +1 more source

Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats. [PDF]

PLoS ONE, 2017
Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals.
Douglas M Bennion, Jacob D Isenberg, Allison T Harmel, Kelly DeMars, Alex N Dang, Chad H Jones, Megan E Pignataro, Justin T Graham, U Muscha Steckelings, Jon C Alexander, Marcelo Febo, Eric G Krause, Annette D de Kloet, Eduardo Candelario-Jalil, Colin Sumners   +14 more
doaj   +1 more source

THE EFFICACY OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANTAGONISTS OF THE RECEPTORS OF THE 1ST TYPE OF ANGIOTENSIN II IN PATIENTS WITH CORONARY ARTERY DISEASE POSTINFARCTION CARDIOSCLEROSIS COMBINED WITH DIABETES MELLITUS TYPE 2 AND ARTERIAL HYPERTENSION

В мире научных открытий, 2016
The article discusses the effectiveness of 3-month therapy with angiotensin converting enzyme inhibitors fosinopril receptor and antagonists of the angiotensin II valsartan to achieve target BP(
Zarina Vyacheslavovna Bitarovа, Oleg Valeryevich Remizov, Zamira Tatarbekovna Astakhova, Zalina Aslanbekovna Toguzova   +3 more
doaj   +1 more source

Effect of Irbesartan on Chemerin in the Renal Tissues of Diabetic Rats

Kidney & Blood Pressure Research, 2015
Background/Aims: Chemerin was introduced as a novel adipokine that plays a crucial role in insulin signaling and diabetic nephropathy. Serum chemerin levels are significantly elevated in type 2 diabetes patients with macroalbuminuria.
Qiu-Xia Yu, Hong Zhang, Wen-Hui Xu, Fei Hao, Su-Lai Liu, Meng-Meng Bai, Jia-Wei Mu, Hui-Juan Zhang   +7 more
doaj   +1 more source

Assessment of cardiac hemodynamics indicators in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor A1166C gene polymorphism

Zaporožskij Medicinskij Žurnal, 2018
Aim of study is to estimate the indicators of cardiac hemodynamics in patients with arterial hypertension and non-alcoholic fatty liver disease depending on angiotensin II type 1 receptor (A1166C) gene polymorphism. Materials and methods.
O. Ya. Babak, M. M. Zaitseva
doaj   +1 more source

The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke

BMC Neuroscience
Background Astrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity.
Daniel Navin Olschewski, Nilufar Nazarzadeh, Felix Lange, Anna Maria Koenig, Christina Kulka, Jella-Andrea Abraham, Stefan Johannes Blaschke, Rudolf Merkel, Bernd Hoffmann, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger, Sabine Ulrike Vay   +12 more
doaj   +1 more source

Rosiglitazone, a Ligand to PPARγ, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation

PPAR Research, 2019
Rosiglitazone (RGZ), a peroxisome proliferator-activated receptor gamma (PPARγ) ligand, has been reported to act as insulin sensitizer and exert cardiovascular actions.
María Sánchez-Aguilar, Luz Ibarra-Lara, Leonardo Del Valle-Mondragón, María Esther Rubio-Ruiz, Alicia G. Aguilar-Navarro, Absalom Zamorano-Carrillo, Margarita del Carmen Ramírez-Ortega, Gustavo Pastelín-Hernández, Alicia Sánchez-Mendoza   +8 more
doaj   +1 more source

Eicosapentaenoic and Docosahexaenoic Acids Attenuate Progression of Albuminuria in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundAlbuminuria is a marker of inflammation and an independent predictor of cardiovascular morbidity and mortality. The current study evaluated whether eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation attenuates ...
Tarec K. Elajami, Abdulhamied Alfaddagh, Dharshan Lakshminarayan, Michael Soliman, Madhuri Chandnani, Francine K. Welty   +5 more
doaj   +1 more source