Results 81 to 90 of about 11,078 (168)

易误诊为多发性硬化的伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病1例报道A Case Report of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Easily Misdiagnosed as Multiple Sclerosis

Zhongguo cuzhong zazhi
伴皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病（cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy，CADASIL）是一种常染色体显性遗传性脑小血管疾病。多发性硬化是一种中枢神经系统的炎症性脱髓鞘疾病。两者在临床表现和影像学特征上有较多类似之处，易造成误诊。本文报道１例因颅内和脊髓同时发生病变，最初诊断为多发性硬化，最终经基因检测明确诊断为Notch受体3（Notch ...
吴慧敏, 游咏, 陈斌WU Huimin, YOU Yong, CHEN Bin
doaj   +1 more source

Transforming growth factor beta-1 promotes migration and invasion of ovarian epithelial carcinoma cells through TRAF6-mediated activation of Notch3 signaling pathway

Zhongguo aizheng zazhi, 2018
Background and purpose: Abnormal expression and amplification of transforming growth factor beta 1 (TGF-β1) and Notch3 in ovarian carcinoma tissues are associated with metastasis and low survival rate, respectively.
周韵娇, 王婧姝, 梁　凡
doaj  

Synergistic effects of mutation and glycosylation on disease progression

Frontiers in Molecular Biosciences
Glycosylation, a post-translational modification, plays a crucial role in proper localization and function of proteins. It is regulated by multiple glycosyltransferases and can be influenced by various factors.
Shodai Suzuki, Motoyuki Itoh, Motoyuki Itoh, Motoyuki Itoh   +3 more
doaj   +1 more source

An in trans NOTCH3 loss-of-function variant modifies disease severity in CADASIL: A family-based study. [PDF]

J Chin Med Assoc
Lan SC, Liu YH, Lan J, Liao YC, Lan MY, Lee YC, Lee YC.   +6 more
europepmc   +1 more source

A novel missense variant Cys559Gly in <i>NOTCH3</i> in CADASIL family and vascular lesions in patients with migraine. [PDF]

Postep Psychiatr Neurol
Jastrzębski K, Kępczyński Ł, Plucińska A, Kowalska-Gałecka M, Gajos A.   +4 more
europepmc   +1 more source

Decoding notch signaling pathway: an updated insight into its role in colorectal cancer progression and therapy. [PDF]

Cancer Cell Int
Molavand M, Asadi A, Majidinia M, Yousefi B.   +3 more
europepmc   +1 more source

Shared molecular features and candidate pathways underlying gastric cancer-depression comorbidity: a systems biology analysis. [PDF]

Front Bioinform
Liu B, Hou B, Zhao Y, Niu J, Hou J, He J, Liu F.   +6 more
europepmc   +1 more source

Integrative analysis of single-cell RNA sequencing, bulk RNA sequencing, and proteomic data identified NOTCH3 as a hub gene contributing to human intervertebral disc fibrosis. [PDF]

Sci Rep
Ding Q, Chen X, Zheng Q, Dou Q, Zuo C, Wang Q, Shen C.   +6 more
europepmc   +1 more source

Inflammatory CADASIL: the cross-link between CADASIL and multiple sclerosis: a report of two cases and systematic review of the literature. [PDF]

BMC Neurol
Ahmed AM, Mistry N, Gehad AS, Hassan AM.
europepmc   +1 more source

Correction: Endothelial cells regulate mesangial cells through the Dll4/Notch3 axis to participate in glomerular injury in lupus nephritis. [PDF]

Front Immunol
Guo H, Mao Y, Wang Y, Yu B, Gu Z, Yao C, Da Z.   +6 more
europepmc   +1 more source