Results 1 to 10 of about 15,145 (164)

Calcitriol and Tacalcitol Modulate Th17 Differentiation Through Osteopontin Receptors: Age-Dependent Insights from a Mouse Breast Cancer Model [PDF]

open access: yesImmunoTargets and Therapy
Aleksandra Strzykalska-Augustyniak, Mateusz Psurski, Honorata Zachary, Beata Filip-Psurska, Dagmara Kłopotowska, Magdalena Milczarek, Marta Świtalska, Martyna Stachowicz-Suhs, Natalia Łabęd&zacute ...
Strzykalska-Augustyniak A   +11 more
doaj   +2 more sources

The Immunological Role of Vitamin D in Primary Immunodeficiencies: A Narrative Review of the Current Literature [PDF]

open access: yesBiomedicines
Vitamin D is a fat-soluble hormone essential for bone mineralization. In addition to this role, vitamin D is known for its immunomodulatory effects through its binding to intracellular vitamin D receptors (VDRs), which translocate to the nucleus of ...
Emanuela Zumbo   +4 more
doaj   +2 more sources

Vitamin D, vitamin D binding protein, vitamin D receptor levels and cardiac dysautonomia in patients with multiple sclerosis: a cross-sectional study [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2020
Vitamin D is a pleiotropic steroid hormone that modulates the autonomic balance. Its deficiency has been described as an environmental risk factor for multiple sclerosis (MS).
Tülin Aktürk   +5 more
doaj   +1 more source

Calcitriol-Mediated Hypercalcemia, Somatostatin Receptors Expression and 25-Hydroxyvitamin D3-1α- Hydroxylase in GIST Tumors

open access: yesFrontiers in Endocrinology, 2022
Hypercalcemia is a common complication in cancer patients Mainly caused by Parathyroid hormone-related protein (PTHrP) secretion and metastasis. Calcitriol secretion is a rare source of hypercalcemia in solid tumors, especially in gastrointestinal ...
Yiraldine Herrera-Martínez   +22 more
doaj   +1 more source

IL-33, IL-37, and Vitamin D Interaction Mediate Immunomodulation of Inflammation in Degenerating Cartilage

open access: yesAntibodies, 2021
Chronic joint inflammation due to increased secretion of pro-inflammatory cytokines, the accumulation of inflammatory immune cells (mainly macrophages), and vitamin D deficiency leads to cartilage degeneration and the development of osteoarthritis (OA ...
Vikrant Rai   +2 more
doaj   +1 more source

Peptide receptor radionuclide therapy controls inappropriate calcitriol secretion in a pancreatic neuro-endocrine tumor: a case report

open access: yesBMC Gastroenterology, 2020
Background Hypercalcemia of malignancy is not uncommon in patients with advanced stage cancer. In rare cases the cause of the hypercalcemia is excessive production of calcitriol, the active form of vitamin D.
Maarten Haemels   +5 more
doaj   +1 more source

Physiological Basis for Using Vitamin D to Improve Health

open access: yesBiomedicines, 2023
Vitamin D is essential for life—its sufficiency improves metabolism, hormonal release, immune functions, and maintaining health. Vitamin D deficiency increases the vulnerability and severity of type 2 diabetes, metabolic syndrome, cancer, obesity, and ...
Sunil J. Wimalawansa
doaj   +1 more source

Vitamin D and Glomerulonephritis

open access: yesMedicina, 2021
Vitamin D presents a plethora of different functions that go beyond its role in skeletal homeostasis. It is an efficient endocrine regulator of the Renin–Angiotensin–Aldosterone System (RAAS) and erythropoiesis, exerts immunomodulatory effects, reduces ...
Guido Gembillo   +4 more
doaj   +1 more source

Analysis of the interaction of calcitriol with the disulfide isomerase ERp57 [PDF]

open access: yes, 2016
Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the ...
Altieri, Fabio   +7 more
core   +1 more source

A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle [PDF]

open access: yes, 2011
Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Martin-Tereso Lopez, J.   +1 more
core   +2 more sources

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