Results 31 to 40 of about 15,145 (164)

The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]

open access: yes, 2012
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Berger U   +13 more
core   +2 more sources

Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]

open access: yes, 2017
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover   +6 more
core   +2 more sources

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis   +19 more
wiley   +1 more source

Vitamin D Pretreatment to Prevent the Risk of Postoperative Hypocalcemic Complications After Parathyroidectomy in Primary Hyperparathyroidism: A Systematic Review and Meta‐Analysis

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Parathyroidectomy is the treatment for primary hyperparathyroidism, yet postoperative hypocalcemia and hungry bone syndrome remain common. Vitamin D deficiency has been suggested as a modifiable risk factor, but evidence supporting preoperative supplementation is inconsistent.
Matthew Gynn   +2 more
wiley   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Effect of paricalcitol vs calcitriol on hemoglobin levels in chronic kidney disease patients: a randomized trial [PDF]

open access: yes, 2015
Recent studies suggest that vitamin D deficiency represents an additional cofactor of renal anemia, with several mechanisms accounting for this relationship.
Andreucci, Michele   +6 more
core   +8 more sources

The health benefits of vitamin D relevant for tuberculosis [PDF]

open access: yesJournal of Medical Biochemistry, 2014
Vitamin D has an important role in numerous physiological functions. Vitamin D receptors are characterized by polymorphisms and presence in different tissues including a number of cells of the immune system.
Škodrić-Trifunović Vesna   +7 more
doaj  

The role of calcium, calcitriol and its receptors in [PDF]

open access: yes, 2010
The mechanism of regulation of Parathyroidhormone (PTH)is complex, and diverse factors are involved: the fundamental ones are calcium, calcitriol and phosphorus. Calcium and calcitriol's mechanism of action takes place through its specific receptors, the
Cannata, J.B. (Jorge)   +2 more
core  

Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients

open access: yesFrontiers in Pharmacology, 2018
Bile acids (BAs) are amphiphilic molecules with 24 carbon atoms and consist of a hydrophobic and a rigid steroid nucleus, to which are attached a hydrophilic hydroxyl group and a flexible acidic aliphatic side chain. The steroidal core of BAs constitutes
Tanja M. Šarenac, Momir Mikov
doaj   +1 more source

Impaired Insulin sensitivity and Insulin secretion in Haemodialysis patients with and without Secondary Hyperparathyroidism [PDF]

open access: yes, 2004
The aim of our study was to investigate insulin sensitivity and beta cell function in hemodialysis (HD) patients without diabetes. We hypothesized that parathyroid gland function was a determinant of insulin sensitivity and/or beta cell function.
Gluvic, Zoran M.   +5 more
core  

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