Results 71 to 80 of about 7,919 (172)

High expression of co-stimulatory and adhesion molecules are observed on eosinophils during human Schistosoma mansoni infection

Memorias do Instituto Oswaldo Cruz, 2006
Herein we have focused attention on major phenotypic features of peripheral blood eosinophils from chronic Schistosoma mansoni-infected patients. For this purpose, detailed immunophenotypic profiles of a range of cell surface markers were performed ...
Denise Silveira-Lemos, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Lúcia Fraga Alves Oliveira, Rodrigo Corrêa-Oliveira   +4 more
doaj   +1 more source

Grape seed extract proanthocyanidins downregulate HIV- 1 entry coreceptors, CCR2b, CCR3 and CCR5 gene expression by normal peripheral blood mononuclear cells

Biological Research, 2002
Flavonoids and related polyphenols, in addition to their cardioprotective, anti-tumor, anti-inflammatory, anti-carcinogenic and anti-allergic activities, also possess promising anti-HIV effects.
MADHAVAN P NAIR, CHITHAN KANDASWAMI, SUPRIYA MAHAJAN, HARIKRISHNA N NAIR, RAM CHAWDA, THOMAS SHANAHAN, STANLEY A SCHWARTZ   +6 more
doaj  

CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets

Journal of Inflammation Research, 2021
Fangteng Liu,1,2 Hengyu Wu1 1Department of Breast Surgery, The Third Hospital of Nanchang, Nanchang, Jiangxi, 330009, People’s Republic of China; 2Faculty of Medicine, University of Munich, Munich, 80336, GermanyCorrespondence: Hengyu Wu Tel +86 ...
Liu F, Wu H
doaj  

AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Mast cells and basophils, historically defined by their pathogenic roles in allergic diseases and type I hypersensitivity, are increasingly recognized as influential participants in cancer biology. Emerging research in AllergoOncology highlights their plasticity, diverse functions, and significance beyond classical contributions to allergy ...
Jack Alder, Katie E. Lacy, Debra H. Josephs, James Spicer, Heather J. Bax, Sophia N. Karagiannis, Jitesh Chauhan   +6 more
wiley   +1 more source

Chemokines and chemokine receptors expression in the lesions of patients with American cutaneous leishmaniasis

Memorias do Instituto Oswaldo Cruz, 2013
American cutaneous leishmaniasis (ACL) presents distinct active clinical forms with different grades of severity, known as localised (LCL), intermediate (ICL) and diffuse (DCL) cutaneous leishmaniasis. LCL and DCL are associated with a polarised T-helper
Nilka Luisa Diaz, Olga Zerpa, Felix Jacobo Tapia   +2 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, Volume 20, Issue 3, Page 753-778, March 2026.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Functional expression of the eotaxin receptor CCR3 in CD30+ cutaneous T-cell lymphoma

Blood, 2003
Little is known about mechanisms involved in skin-specific homing of cutaneous T-cell lymphoma (CTCL). Chemokine/chemokine receptor interactions have been implicated in the homing of lymphoma cells to various tissue sites. We investigated tissue samples and tumor cell suspensions of patients with CD30+ CTCL (n = 8) and CD30− CTCL (mycosis fungoides, n =
Kleinhans, M, Tun-Kyi, A, Gilliet, M, Kadin, M E, Dummer, R, Burg, G, Nestle, F O   +6 more
openaire   +4 more sources

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

A Study of CD4, CCR3, CCR4, CCR5, CXCR3 Expression in Peripheral Blood Lymphocytes of Patients with Gastric Cancer

مجله دانشکده پزشکی اصفهان, 2012
Background: Based on the different expression of chemokine receptors in immune cells, we hypothesized that there would be an alteration in the relative expression of these receptors by T helper cells (Th1 and Th2) during the progression of a malignancy ...
Alireza Andalib, Hassan Dolabi, Abbas Rezaei, Mohamad Reza Maracy, Seyed Javad Hasheminia   +4 more
doaj  

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

Current Biology, 1997
The chemokine eotaxin is produced at sites of allergic inflammation, binds selectively to the chemokine receptor CCR3 and attracts eosinophil and basophil leukocytes, which express high numbers of this receptor. Responses of T lymphocytes to eotaxin have not been reported so far. We have investigated the expression of CCR3 in T lymphocytes and analysed
Gerber BO, Zanni MP, Uguccioni M, Loetscher M, Mackay CR, Pichler WJ, Yawalkar N, Baggiolini M, Moser B   +8 more
openaire   +3 more sources