Results 101 to 110 of about 275,691 (287)

The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases

Frontiers in Endocrinology, 2019
Chemokine receptors are members of the G protein-coupled receptor superfamily. These receptors are intimately involved in cell movement, and thus play a critical role in several physiological and pathological situations that require the precise ...
Eva M. García-Cuesta, César A. Santiago, Jesús Vallejo-Díaz, Yasmina Juarranz, José Miguel Rodríguez-Frade, Mario Mellado   +5 more
doaj   +1 more source

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Weidenbusch, Marc, Anders, Hans-Joachim
core   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

Arthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J. Braaten, Gary A. Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells. [PDF]

, 2017
ROR1 (receptor tyrosine kinase-like orphan receptor 1) is a conserved, oncoembryonic surface antigen expressed in chronic lymphocytic leukemia (CLL).
A Butrym, A Stacchini, AH Daneshmanesh, AM Brunati, B Cui, C Scielzo, C Scielzo, C Wilson, D Kitamura, DA Dehring, E Roszmusz, E Ten Hacken, E ten Hacken, ES Witze, F Frezzato, GF Widhopf II, HE Broome, J Skokowa, J Yu, J Yu, JA Burger, JA Di Paolo, JJ Hao, K Alexandropoulos, K Kurokawa, M Lettau, M Muzio, M Rodriguez-Niedenfuhr, MY Choi, N Martinez-Quiles, P Masiakowski, P Masiakowski, PJ Cavnar, S Baskar, S Mukherjee, T Fukuda, T Uruno, TS Gomez, WC Forrester, WC Forrester, X Qi, Y Suzuki, Y Takemoto, Y Yamanashi, YK Xu, Z Weng   +45 more
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Identification of transmembrane domains that regulate spatial arrangements and activity of prokineticin receptor 2 dimers [PDF]

, 2014
The chemokine prokineticin 2 (PK2) activates its cognate G protein-coupled receptor (GPCR) PKR2 to elicit various downstream signaling pathways involved in diverse biological processes.
Caltabiano, G, Hanyaloglu, AC, Miele, R, Sposini, S   +3 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human.

PLoS ONE, 2008
Mesenchymal stem cells (MSCs) are non-haematopoeitic, stromal cells that are capable of differentiating into mesenchymal tissues such as bone and cartilage.
Giselle Chamberlain, Karina Wright, Antal Rot, Brian Ashton, Jim Middleton   +4 more
doaj   +1 more source

Deciphering Small Molecule Diffusion Parameters Across Light Responsive Polymersome Membranes

Advanced Functional Materials, EarlyView.
Light‐responsive polymersomes bearing donor–acceptor Stenhouse adducts (DASAs) enable programmable control over small‐molecule transport across synthetic membranes. By systematically varying DASA density, an optimal functionalization regime is identified that maximizes light‐gated permeability.
Farzina Matubbar, Beyzanur Kaya, Buse Ipek, Tenzin Dorjee, Shoghik Hakobyan, Mohamed Chami, Julien E. Gautrot, Omar Rifaie‐Graham   +7 more
wiley   +1 more source

Cytokines of Birds: Conserved Functions [PDF]

, 2001
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F., Kaspers, Bernd, Puehler, Florian, Schneider, Kirsten, Staeheli, Peter   +4 more
core   +1 more source