Results 21 to 30 of about 26,449 (216)

JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats

open access: yesMolecular Pain, 2012
Background Proopiomelanocortin (POMC)-derived beta-endorphin1-31 from immune cells can inhibit inflammatory pain. Here we investigated cytokine signaling pathways regulating POMC gene expression and beta-endorphin production in lymphocytes to augment ...
Busch-Dienstfertig Melanie   +4 more
doaj   +1 more source

Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus

open access: yesMemorias do Instituto Oswaldo Cruz, 1996
The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus.
Geraldo A De Carli   +4 more
doaj   +1 more source

The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]

open access: yes, 2007
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu   +2 more
core   +2 more sources

Restriction of the Mobility of Lymphocyte Immunoglobulin Receptors by Concanavalin A [PDF]

open access: yesProceedings of the National Academy of Sciences, 1972
The induction by anti-immunoglobulin of patch and cap formation on mouse lymphocytes was inhibited by the addition of concanavalin A. This effect was reversed by α-methyl-D-mannoside, a competitive inhibitor of the binding of concanavalin A. Concanavalin A prevented both patch and cap formation, in contrast to the metabolic inhibitor NaN
I, Yahara, G M, Edelman
openaire   +2 more sources

Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells

open access: yesFrontiers in Cell and Developmental Biology, 2020
It is a well-documented event that fibroblast growth factors (FGFs) regulate liver development and homeostasis in autocrine, paracrine, and endocrine manners via binding and activating FGF receptors (FGFRs) tyrosine kinase in hepatocytes. Recent research
Cong Wang   +11 more
doaj   +1 more source

Estradiol-induced inhibition of endoplasmic reticulum stress normalizes splenic CD4 + T lymphocytes following hemorrhagic shock

open access: yesScientific Reports, 2021
The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum stress (ERS) following hemorrhage.
Peng Wang   +14 more
doaj   +1 more source

A Novel Antigen Sensitive to Calcium Chelation That is Associated with the Tip Links and Kinocilial Links of Sensory Hair Bundles [PDF]

open access: yes, 2003
Tip links are extracellular, cell-surface-associated filaments of unknown molecular composition that are thought to gate the mechanotransducer channel of the sensory hair cell.
Goodyear, Richard J, Richardson, Guy P
core   +2 more sources

The rolle of carbohydrate component of neutrophil membrane glycoprotein receptors for change of its functional activity at patients with acute coronari syndroms and its combination with diabetes mellitus type 2

open access: yesБюллетень сибирской медицины, 2002
The aim of this work is to gind ont influence of сarbohydrate сomponent of membrane glycoprotein receptors on the change of its functional activity at patients with acute coronari syndromes and its combination with diabetes mellitus type 2.
V. F. Kiritchuk   +2 more
doaj   +1 more source

Development of Mannose-Modified Carboxylated Curdlan-Coated Liposomes for Antigen Presenting Cell Targeted Antigen Delivery

open access: yesPharmaceutics, 2020
Specific delivery to antigen presenting cells (APC) and precise control of the intracellular fate of antigens are crucial to induce cellular immunity that directly and specifically attacks cancer cells.
Eiji Yuba   +4 more
doaj   +1 more source

Synthesis & Evaluation of Novel Mannosylated Neoglycolipids for Liposomal Delivery System Applications

open access: yesPharmaceutics, 2022
Glycosylated NPs, including liposomes, are known to target various receptors involved in cellular carbohydrate transport, of which the mannoside binding receptors are attracting particular attention for their expression on various immune cells, cancers ...
Leila Mousavifar   +11 more
doaj   +1 more source

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