Results 21 to 30 of about 611,331 (287)

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

open access: yesHaematologica, 2010
Background Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplant is ...
Virna Marin   +9 more
doaj   +1 more source

Extracellular ATP drives systemic inflammation, tissue damage and mortality [PDF]

open access: yes, 2014
Systemic inflammatory response syndromes (SIRS) may be caused by both infectious and sterile insults, such as trauma, ischemia-reperfusion or burns. They are characterized by early excessive inflammatory cytokine production and the endogenous release of ...
Brouckaert, Peter   +4 more
core   +1 more source

Perspective: Daniela Novick, cytokines and their receptors

open access: yesFrontiers in Immunology, 2023
This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several ...
Pietro Ghezzi   +2 more
doaj   +1 more source

Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors [PDF]

open access: yes, 2014
Article Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune ...
Gow, Neil A R   +9 more
core   +3 more sources

Opioid and nociceptin receptors regulate cytokine and cytokine receptor expression [PDF]

open access: yesCellular Immunology, 2008
Opioids were originally discovered because of their ability to induce analgesia, but further investigation has shown that the opioids regulate the function of cells involved in the immune response. We suggest that the regulation of cytokine, chemokine, and cytokine receptor expression is a critical component of the immunomodulatory activity of the ...
Christine Happel   +3 more
openaire   +3 more sources

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

open access: yes, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C   +27 more
core   +1 more source

Chicken BAFF [PDF]

open access: yes, 2004
Members of the tumor necrosis factor (TNF) family play key roles in the regulation of inflammation, immune responses and tissue homeostasis. Here we describe the identification of the chicken homologue of mammalian B cell activating factor of the TNF ...
Göbel, Thomas W. F.   +6 more
core   +1 more source

Control of cytokine production by human Fc gamma receptors: implications for pathogen defense and autoimmunity

open access: yesFrontiers in Immunology, 2015
Control of cytokine production by immune cells is pivotal for counteracting infections via orchestration of local and systemic inflammation. Although their contribution has long been underexposed, it has recently become clear that human Fc gamma ...
Lisa T C Vogelpoel   +3 more
doaj   +1 more source

Dysregulated homeostasis of acetylcholine levels in immune cells of RR-multiple sclerosis patients [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is characterized by pro-inflammatory cytokine production. Acetylcholine (ACh) contributes to the modulation of central and peripheral inflammation.
Biagioni, Stefano   +11 more
core   +2 more sources

P1 receptors and cytokine secretion [PDF]

open access: yesPurinergic Signalling, 2007
Evidence has accumulated in the last three decades to suggest tissue protection and regeneration by adenosine in multiple different cell types. Adenosine produced in hypoxic or inflamed environments reduces tissue injury and promotes repair by receptor-mediated mechanisms.
M.P. Abbracchio, S. Ceruti
openaire   +3 more sources

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