Results 21 to 30 of about 646,725 (280)
PLoS ONE, 2020 Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions.
Sofie Mossner +5 more
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Медицинская иммунология, 2023 TNFa is a pro-inflammatory cytokine that is signaled through type 1 (TNFR1) and type 2 (TNFR2) receptors. TNFR1 normally mediates apoptosis, cell survival, and cytokine secretion, while TNFR2 selectively mediates cell survival and cytokine secretion. But
Yu. A. Lopatnikova +6 more
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Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]
, 2014 Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Marelli-Berg, F +3 more
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libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources
The evolution of IL-4 and IL-13 and their receptor subunits [PDF]
, 2015 Peer ...
Secombes, Christopher J., Wang, Tiehui
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Evolution of γ chain cytokines: Mechanisms, methods and applications
Computational and Structural Biotechnology Journal, 2022 The common γ chain family of cytokines and their receptors play fundamental roles in the immune system. Evolutionary studies of γ chain cytokines have elegantly illustrated how the immune system adapts to ever-changing environmental conditions.
Magdalena Antczak +4 more
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The case for absolute ligand discrimination : modeling information processing and decision by immune T cells [PDF]
, 2015 Some cells have to take decision based on the quality of surroundings ligands, almost irrespective of their quantity, a problem we name "absolute discrimination". An example of absolute discrimination is recognition of not-self by immune T Cells. We show
Altan-Bonnet, Grégoire, François, Paul
core +2 more sources
Evolution of Class I cytokine receptors
BMC Evolutionary Biology, 2007 Background The Class I cytokine receptors have a wide range of actions, including a major role in the development and function of immune and blood cells. However, the evolution of the genes encoding them remains poorly understood. To address this we have
Ward Alister C, Liongue Clifford
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Cytokine Receptor Endocytosis: New Kinase Activity-Dependent and -Independent Roles of PI3K
Frontiers in Endocrinology, 2017 Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development.
Lily Jun-shen Huang +2 more
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Сибирский онкологический журнал, 2023 T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However, checkpoint expressing T cell compartment includes different subsets, and their dysregulation ...
E. V. Batorov +7 more
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