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The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo+10 more
doaj +1 more source
VEGF: An essential mediator of both angiogenesis and endochondral ossification [PDF]
During bone growth, development, and remodeling, angiogenesis as well as osteogenesis are closely associated processes, sharing some essential mediators.
Dai, J, Rabie, ABM
core +1 more source
Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). [PDF]
Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.
Birgitte P S Jacky+12 more
doaj +1 more source
A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice [PDF]
The binding of vascular endothelial growth factor (VEGF) to VEGF receptor-2 (VEGFR-2) on the surface of vascular endothelial cells stimulates many steps in the angiogenic pathway.
A Janssen+52 more
core +1 more source
Fibroblast growth factor receptors as novel therapeutic targets in SNF5-deleted malignant rhabdoid tumors. [PDF]
Malignant rhabdoid tumors (MRTs) are aggressive pediatric cancers arising in brain, kidney and soft tissues, which are characterized by loss of the tumor suppressor SNF5/SMARCB1.
Simon Wöhrle+17 more
doaj +1 more source
Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute signaling circuits that transmit signals across the plasma membrane, regulating pivotal cellular processes like differentiation, migration, proliferation, and apoptosis.
Marta Latko+6 more
doaj +1 more source
The Fibroblast Growth Factor signaling pathway
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF receptors (FGFRs).
D. Ornitz, N. Itoh
semanticscholar +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo+11 more
core +1 more source
Objective To observe the developmental process of murine meniscus after birth and investigate the expression patterns of 3 types of fibroblast growth factor receptors (FGFRs) during this process. Methods Mice at different ages (1 d old and 1, 2, 4, 6 and
LI Fangfang+4 more
doaj +1 more source
FGFR4 (fibroblast growth factor receptor 4) [PDF]
Peer ...
Peláez-García, A+2 more
openaire +4 more sources