Results 11 to 20 of about 26,234 (229)
KIR Receptors as Key Regulators of NK Cells Activity in Health and Disease
Cells, 2021 Natural killer (NK) cells are part of the cellular immune response. They target mainly cancer and virally infected cells. To a high extent cytotoxic activity of NK cells is regulated inter alia by signals from killer immunoglobulin-like receptors (KIR ...
Joanna Dębska-Zielkowska +6 more
doaj +5 more sources
Effects of peptide on NK cell-mediated MHC I recognition
Frontiers in Immunology, 2014 The inhibitory receptors for MHC class I have a central role in controlling NK cell activity. Soon after their discovery it was found that these receptors have a degree of peptide selectivity.
Salim Iqbal Khakoo +2 more
doaj +2 more sources
Immunological Aspects of Infertility—The Role of KIR Receptors and HLA-C Antigen
Cells, 2023 The mechanisms of immune tolerance of a mother against an antigenically foreign fetus without a concomitant loss of defense capabilities against pathogens are the factors underlying the success of a pregnancy.
Anna Wasilewska +5 more
doaj +3 more sources
Natural Killer (NK) Cell Alloreactivity in Haploidentical Stem Cell Transplantation [PDF]
CellsThis paper conducts a literature review on the role of natural killer cells in haploidentical hematopoietic stem cell transplantation. Theoretical concepts related to KIR genes are introduced regarding their structure, nomenclature, genetic organization,
Mar Luis-Hidalgo +3 more
doaj +2 more sources
Journal of Hematology & Oncology, 2016 Background Interim positron emission tomography after 2 cycles of ABVD (iPET-2) is a good predictor of outcome in advanced-stage classic Hodgkin lymphoma.
Giorgio La Nasa +13 more
doaj +3 more sources
Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon. [PDF]
J Immunol Res, 2021 The biological reason(s) behind persistent mother-to-child transmission (MTCT) of HIV (albeit at reduced rate compared to the preantiretroviral therapy era) in spite of the successful implementation of advanced control measures in many African countries remains a priority concern to many HIV/AIDS control programs.
Luc-Aimé KS +5 more
europepmc +5 more sources
Role of KIR Receptor in NK Regulation during Viral Infections [PDF]
Immuno, 2021 Natural Killer (NK) cells are key effectors of the innate immune system which represent the first line of defense against viral infections. NK cell activation depends on the engagement of a complex receptor repertoire expressed on their surface, consisting of both activating and inhibitory receptors.
Sabrina Rizzo +5 more
openaire +2 more sources
Recruitment of activation receptors at inhibitory NK cell immune synapses. [PDF]
PLoS ONE, 2008 Natural killer (NK) cell activation receptors accumulate by an actin-dependent process at cytotoxic immune synapses where they provide synergistic signals that trigger NK cell effector functions.
Nicolas Schleinitz +2 more
doaj +1 more source
KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans
Cell Reports, 2023 Summary: Subsets of the human CD8+ T cell population express inhibitory NK cell receptors, such as killer immunoglobulin-like receptors (KIRs) and NKG2A.
Seong Jin Choi +7 more
doaj +1 more source
Killer-cell Immunoglobulin-like Receptor (KIR) Nomenclature Report, 2002 [PDF]
Human Immunology, 2003 During discussion at the WHO Nomenclature Committee for Factors of the HLA System meeting in Victoria, Canada in May 2002, it was decided to form a subcommittee to coordinate the naming of alleles of the genes encoding the killer-cell immunoglobulin-like receptors (KIRs) (Marsh et al., 2002).
S G E, Marsh +13 more
openaire +4 more sources