Results 11 to 20 of about 15,494 (227)

KIR receptors and HLA-C in the maintenance of pregnancy [PDF]

Tissue Antigens, 2007
The present study demonstrated that patients who have recurrent spontaneous abortions (RSA) presented a decreased number of killer immunoglobulin-like inhibitory receptors (KIR), in particular KIR2DL2.
C. Y. Marcos, Williams, F., F. Williams, Paladino, Natalia, L. Arruvito, Fainboim, Leonardo, Flores, Ana Claudia, Marcos, C. Y., L. Fainboim, D. Middleton, N. Paladino, A. C. Flores, Middleton, D., Arruvito, Maria Lourdes   +13 more
core   +4 more sources

Identification of the ancestral killer immunoglobulin-like receptor gene in primates

BMC Genomics, 2006
Background Killer Immunoglobulin-like Receptors (KIR) are essential immuno-surveillance molecules. They are expressed on natural killer and T cells, and interact with human leukocyte antigens.
Coggill Penny, Vernikos George S, Piatak Mike, Andersen Hanne, Bashirova Arman, Sambrook Jennifer G, Lifson Jeff D, Carrington Mary, Beck Stephan   +8 more
doaj   +2 more sources

Ligand specificity of Killer cell Immunoglobulin-like Receptors: a brief history of KIR [PDF]

Frontiers in Immunology, 2012
Natural Killer (NK) cells are a subset of innate lymphoid cells specialized for cytotoxicity and production of inflammatory cytokines such as IFNγ. As such, they are presumed to be impor-tant for early control of infections with intracellular pathogens ...
John Trowsdale, Jeroen van Bergen, John eTrowsdale, Jeroen eVan Bergen   +3 more
core   +4 more sources

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans. [PDF]

PLoS Genetics, 2013
Interactions between HLA class I molecules and killer-cell immunoglobulin-like receptors (KIR) control natural killer cell (NK) functions in immunity and reproduction.
Paul J Norman, Jill A Hollenbach, Neda Nemat-Gorgani, Lisbeth A Guethlein, Hugo G Hilton, Marcelo J Pando, Kwadwo A Koram, Eleanor M Riley, Laurent Abi-Rached, Peter Parham   +9 more
doaj   +2 more sources

Expression patterns of killer cell immunoglobulin-like receptors (KIR) of NK-cell and T-cell subsets in Old World monkeys. [PDF]

PLoS ONE, 2013
The expression of killer cell immunoglobulin-like receptors (KIR) on lymphocytes of rhesus macaques and other Old World monkeys was unknown so far.
Meike Hermes, Christina Albrecht, Annette Schrod, Markus Brameier, Lutz Walter   +4 more
doaj   +2 more sources

Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon. [PDF]

J Immunol Res, 2021
The biological reason(s) behind persistent mother-to-child transmission (MTCT) of HIV (albeit at reduced rate compared to the preantiretroviral therapy era) in spite of the successful implementation of advanced control measures in many African countries remains a priority concern to many HIV/AIDS control programs.
Luc-Aimé KS, Louis-Marie Y, Gabriel LE, Yengo CK, Esemu Livo F, Assob NJC.   +5 more
europepmc   +5 more sources

Role of KIR Receptor in NK Regulation during Viral Infections [PDF]

Immuno, 2021
Natural Killer (NK) cells are key effectors of the innate immune system which represent the first line of defense against viral infections. NK cell activation depends on the engagement of a complex receptor repertoire expressed on their surface, consisting of both activating and inhibitory receptors.
Sabrina Rizzo, Giovanna Schiuma, Silvia Beltrami, Valentina Gentili, Roberta Rizzo, Daria Bortolotti   +5 more
openaire   +2 more sources

Killer-cell Immunoglobulin-like Receptor (KIR) Nomenclature Report, 2002 [PDF]

Human Immunology, 2003
During discussion at the WHO Nomenclature Committee for Factors of the HLA System meeting in Victoria, Canada in May 2002, it was decided to form a subcommittee to coordinate the naming of alleles of the genes encoding the killer-cell immunoglobulin-like receptors (KIRs) (Marsh et al., 2002).
S G E, Marsh, P, Parham, B, Dupont, D E, Geraghty, J, Trowsdale, D, Middleton, C, Vilches, M, Carrington, C, Witt, L A, Guethlein, H, Shilling, C A, Garcia, K C, Hsu, H, Wain   +13 more
openaire   +5 more sources

Expression of KIR and C-type lectin receptors in Behcet's disease [PDF]

Rheumatology, 2004
Behçet's disease (BD) is a multisystemic disorder with a possible underlying pathology of immune-mediated vasculitis. Genetic susceptibility associated with HLA-B*51 and B*2702 has been implicated in its pathogenesis. Considering the recently defined regulatory mechanisms of NK cells through HLA class I binding receptors, we hypothesized that ...
Kamali, S, Ocal, L, Inanc, M, Gul, A, Cefle, AYŞE, Saruhan-Direskeneli, G, Uyar, FA, Onder, SC, Eksioglu-Demiralp, E   +8 more
openaire   +4 more sources

Killer cell immunoglobulin‐like receptors (KIR) of the African‐origin sabaeus monkey: evidence for recombination events in the evolution of KIR [PDF]

European Journal of Immunology, 2005
AbstractKiller cell immunoglobulin (Ig)‐like receptors (KIR) were characterized in the West African sabaeus monkey (Chlorocebus sabaeus) to elucidate the mechanism by which diversity evolves in this family of molecules. Complementary DNA encoding four forms of KIR molecules, including KIR3DL, KIR2DL4, KIR2DL5, and KIR3DH forms, were identified in two ...
Karen L, Hershberger, Jessica, Kurian, Bette T, Korber, Norman L, Letvin   +3 more
openaire   +2 more sources