Results 11 to 20 of about 13,983 (185)

Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon. [PDF]

J Immunol Res, 2021
The biological reason(s) behind persistent mother-to-child transmission (MTCT) of HIV (albeit at reduced rate compared to the preantiretroviral therapy era) in spite of the successful implementation of advanced control measures in many African countries remains a priority concern to many HIV/AIDS control programs.
Luc-Aimé KS, Louis-Marie Y, Gabriel LE, Yengo CK, Esemu Livo F, Assob NJC.   +5 more
europepmc   +5 more sources

Role of KIR Receptor in NK Regulation during Viral Infections [PDF]

Immuno, 2021
Natural Killer (NK) cells are key effectors of the innate immune system which represent the first line of defense against viral infections. NK cell activation depends on the engagement of a complex receptor repertoire expressed on their surface, consisting of both activating and inhibitory receptors.
Sabrina Rizzo, Giovanna Schiuma, Silvia Beltrami, Valentina Gentili, Roberta Rizzo, Daria Bortolotti   +5 more
openaire   +2 more sources

Killer-cell Immunoglobulin-like Receptor (KIR) Nomenclature Report, 2002 [PDF]

Human Immunology, 2003
During discussion at the WHO Nomenclature Committee for Factors of the HLA System meeting in Victoria, Canada in May 2002, it was decided to form a subcommittee to coordinate the naming of alleles of the genes encoding the killer-cell immunoglobulin-like receptors (KIRs) (Marsh et al., 2002).
S G E, Marsh, P, Parham, B, Dupont, D E, Geraghty, J, Trowsdale, D, Middleton, C, Vilches, M, Carrington, C, Witt, L A, Guethlein, H, Shilling, C A, Garcia, K C, Hsu, H, Wain   +13 more
openaire   +5 more sources

Expression of KIR and C-type lectin receptors in Behcet's disease [PDF]

Rheumatology, 2004
Behçet's disease (BD) is a multisystemic disorder with a possible underlying pathology of immune-mediated vasculitis. Genetic susceptibility associated with HLA-B*51 and B*2702 has been implicated in its pathogenesis. Considering the recently defined regulatory mechanisms of NK cells through HLA class I binding receptors, we hypothesized that ...
Ocal, L, Gul, A, Uyar, FA, Cefle, AYŞE, Onder, SC, Saruhan-Direskeneli, G, Eksioglu-Demiralp, E, Kamali, S, Inanc, M   +8 more
openaire   +4 more sources

KIR receptors and HLA‐C in the maintenance of pregnancy

Tissue Antigens, 2007
AbstractThe present study demonstrated that patients who have recurrent spontaneous abortions (RSA) presented a decreased number of killer immunoglobulin‐like inhibitory receptors (KIR), in particular KIR2DL2. The KIR AA genotype was found increased in comparison with controls. Individuals AA will also be homozygous for 2DL3, which in contrast to 2DL2,
Flores, Ana Claudia, Marcos, C. Y., Paladino, Natalia, Arruvito, Maria Lourdes, Williams, F., Middleton, D., Fainboim, Leonardo   +6 more
openaire   +3 more sources

Killer-Cell Immunoglobulin-like Receptor Diversity in an Admixed South American Population

Cells, 2022
Natural Killer (NK) cells are innate immune cells that mediate antiviral and antitumor responses. NK cell activation and induction of effector functions are tightly regulated by the integration of activating and inhibitory receptors such as killer ...
Marlon Castrillon, Nancy D. Marin, Amado J. Karduss-Urueta, Sonia Y. Velasquez, Cristiam M. Alvarez   +4 more
doaj   +1 more source

Особливості розподілу та частота KIR-генів у жінок із регулярними ранніми репродуктивними втратами

Фактори експериментальної еволюції організмів, 2017
Aim. KIR (killer cell immunoglobulin-like receptors) are the transmembranous glycoprotein receptors, role of which is to activate or inhibit the functional activity of cells, the surfaces of which they are located on.
O. I. Terpyliak, D. V. Zastavna, N. V. Helner, S. V. Osidach   +3 more
doaj   +1 more source

High-Resolution Analysis Identifies High Frequency of KIR-A Haplotypes and Inhibitory Interactions of KIR With HLA Class I in Zhejiang Han

Frontiers in Immunology, 2021
Killer cell immunoglobulin-like receptors (KIR) interact with human leukocyte antigen (HLA) class I molecules, modulating critical NK cell functions in the maintenance of human health.
Sudan Tao, Yanmin He, Katherine M. Kichula, Jielin Wang, Ji He, Paul J. Norman, Faming Zhu   +6 more
doaj   +1 more source

Doenças reumatológicas autoimunes e sua associação com os genes killer immunoglobulin-like receptors Autoimmune rheumatic diseases and their association with killer immunoglobulin-like receptor genes

Revista Brasileira de Reumatologia, 2011
Os genes Killer Immunoglobulin-like Receptors (KIR) expressam-se como receptores que estimulam ou inibem as células Natural Killer (NK). As células NK fazem parte da imunidade inata e através de seus receptores KIR identificam células-alvo que apresentam
Patricia Hartstein Salim, Mariana Jobim, Luiz Fernando Jobim, Ricardo Machado Xavier   +3 more
doaj   +1 more source

Killer cell immunoglobulin-like receptor (KIR) genes in systemic sclerosis [PDF]

Clinical and Experimental Immunology, 2010
Summary A previous study has suggested that the combination KIR2DS2+/KIR2DL2- was related to increased risk for systemic sclerosis (SSc), while others have failed to reproduce this finding. Our objective was to study this matter further and test the association of other KIR genes with SSc. One hundred and ten SSc patients and 115 healthy
P H, Salim, M, Jobim, M, Bredemeier, J A B, Chies, J, Schlottfeldt, J C T, Brenol, L F, Jobim, R M, Xavier   +7 more
openaire   +2 more sources