Results 21 to 30 of about 15,494 (227)
Killer-Cell Immunoglobulin-like Receptor Diversity in an Admixed South American Population
Cells, 2022 Natural Killer (NK) cells are innate immune cells that mediate antiviral and antitumor responses. NK cell activation and induction of effector functions are tightly regulated by the integration of activating and inhibitory receptors such as killer ...
Marlon Castrillon +4 more
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Frontiers in Immunology, 2021 Killer cell immunoglobulin-like receptors (KIR) interact with human leukocyte antigen (HLA) class I molecules, modulating critical NK cell functions in the maintenance of human health.
Sudan Tao +6 more
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Killer cell immunoglobulin-like receptors and their ligands : assessment of potential diagnostic and immunotherapeutic value [PDF]
, 2014 Human natural killer (NK) cells constitute an important arm of the innate immune system, which participates in protection against viral infections and elimination of malignant diseases.
Czaja, Karol Gustaw
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Особливості розподілу та частота KIR-генів у жінок із регулярними ранніми репродуктивними втратами
Фактори експериментальної еволюції організмів, 2017 Aim. KIR (killer cell immunoglobulin-like receptors) are the transmembranous glycoprotein receptors, role of which is to activate or inhibit the functional activity of cells, the surfaces of which they are located on.
O. I. Terpyliak +3 more
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Killer cell immunoglobulin-like receptor (KIR) genes in systemic sclerosis [PDF]
Clinical and Experimental Immunology, 2010 Summary A previous study has suggested that the combination KIR2DS2+/KIR2DL2- was related to increased risk for systemic sclerosis (SSc), while others have failed to reproduce this finding. Our objective was to study this matter further and test the association of other KIR genes with SSc. One hundred and ten SSc patients and 115 healthy
P H, Salim +7 more
openaire +2 more sources
Revista Brasileira de Reumatologia, 2011 Os genes Killer Immunoglobulin-like Receptors (KIR) expressam-se como receptores que estimulam ou inibem as células Natural Killer (NK). As células NK fazem parte da imunidade inata e através de seus receptores KIR identificam células-alvo que apresentam
Patricia Hartstein Salim +3 more
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Identification and diversity of killer cell Ig-like receptors in Aotus vociferans, a New World monkey. [PDF]
PLoS ONE, 2013 Previous BAC clone analysis of the Platyrrhini owl monkey KIRs have shown an unusual genetic structure in some loci. Therefore, cDNAs encoding KIR molecules from eleven Aotus vociferans monkeys were characterized here; ten putative KIR loci were found ...
Diego Garzón-Ospina +4 more
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Effects of peptide on NK cell-mediated MHC I recognition
Frontiers in Immunology, 2014 The inhibitory receptors for MHC class I have a central role in controlling NK cell activity. Soon after their discovery it was found that these receptors have a degree of peptide selectivity.
Salim Iqbal Khakoo +2 more
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Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients
Mediators of Inflammation, 2020 We investigated activation status, cytotoxic potential, and gut homing ability of the peripheral blood Natural Killer (NK) cells in Crohn disease (CD) patients. For this purpose, we compared the expression of different activating and inhibitory receptors
Suzanne Samarani +7 more
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Evolution of NK receptors: a single Ly49 and multiple KIR genes in the cow [PDF]
European Journal of Immunology, 2002 Natural killer (NK) cell receptors for classical MHC class I molecules are encoded by the killer Ig-like receptor (KIR) multigene family in humans and other primates. Mouse NK cells, however, employ a completely different multigene family, the C-type lectin-like Ly49 genes, to perform the same function.
Karina L, McQueen +3 more
openaire +2 more sources