Results 91 to 100 of about 17,556 (218)

Pharmacokinetics and Anti‐Inflammatory Effects of Intramuscular Betamethasone in Exercised Thoroughbred Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan, Jeff Blea, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Mechanisms Underlying Mechanical Responses to Ephedra herb of Isolated Rabbit Urinary Bladder and Urethra, a Possible Stress Urinary Incontinence Therapeutic

Journal of Pharmacological Sciences, 2008
To compare the mechanisms underlying mechanical responses to ephedrine and Ephedra herb, a main component of Kakkon-to, in isolated male and female rabbit urinary bladder and urethral strips, responses of isolated strips to the agents were recorded in ...
Kazuhide Ayajiki, Toshio Kimura, Kohei Yamamizu, Tomio Okamura   +3 more
doaj   +1 more source

Polymyositis And Dermatomyositis - Inflammation, Muscle Structure & Immunosuppressive Treatment [PDF]

, 2012
Polymyositis and dermatomyositis are chronic, inflammatory disorders characterized by muscle weakness, low muscle endurance and by inflammation in skeletal muscle tissues.
Loell, Ingela
core   +1 more source

Transcriptomic Responses to Koi Herpesvirus in Isolated Blood Leukocytes from Infected Common Carp

Viruses
Koi herpesvirus (KHV, CyHV-3) causes severe economic losses in carp farms. Its eradication is challenging due to the establishment of latency in blood leukocytes and other tissues.
Irene Cano, Ellen Blaker, David Hartnell, Audrey Farbos, Karen A. Moore, Adele Cobb, Eduarda M. Santos, Ronny van Aerle   +7 more
doaj   +1 more source

Novel structural determinants of the human neutrophil chemotactic activity of leukotriene B. [PDF]

, 1981
A specific 5(S),12(R)-dihydroxy-eicosa-6,8,10(trans/trans/cis), 14(cis)-tetraenoic acid, designated leukotriene B, is generated by the lipoxygenation and subsequent enzymatic hydration of arachidonic acid in a variety of leukocytes. Leukotriene B elicits
Goetzl, EJ, Pickett, WC
core  

Psoriasis—An Immunological Disease [PDF]

, 1996
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111129/1/jde02714 ...
Alroy, Baadsgaard, Bach, Bata-Csorgo, Berg, Cronstein, Ellis, Enk, Gandangi, Griffiths, Griffiths, Halprin, Hammarstrom, Judge, Menssen, Morganroth, Mueller, Nesde, Rivas, Robinson, Scheinman, Schlaak, Uyemura, Valdimarsson, Voorhees, Voorhees, Weinstein   +26 more
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Concepts of GPCR-controlled navigation in the immune system

, 2019
G-protein-coupled receptor (GPCR) signaling is essential for the spatiotemporal control of leukocyte dynamics during immune responses. For efficient navigation through mammalian tissues, most leukocyte types express more than one GPCR on their surface ...
Boneschansker L, Brandt SL, Chan EC, Filippo K, Freedman NJ, Hjorto GM, Hons M, Katakai T, Kitayama J, Lemos C, Ley K, Miyabe Y, Moussavi‐Harami SF, Proudfoot AEI, Purvanov V, Rot A, Scheiermann C, Schwarz J, Sokol CL, Sotsios Y, Steury MD, Takeda A, Thiriot A, Tomhave ED, Wang Y, Yanagihara S, Zhang Y   +26 more
core   +1 more source

Influence of lipopolysaccharide on proinflammatory gene expression in human corneal, conjunctival and meibomian gland epithelial cells [PDF]

, 2018
PURPOSE: Lipopolysaccharide (LPS), a bacterial endotoxin, is known to stimulate leuokotriene B4 (LTB4) secretion by human corneal (HCECs), conjunctival (HConjECs) and meibomian gland (HMGECs) epithelial cells.
Chen, Di, Darabad, Raheleh Rahimi, Kam, Wendy R., Liu, Yang, Sahin, Afsun, Sullivan, David A.   +5 more
core   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source