Results 161 to 170 of about 17,556 (218)

Mitochondria as Inducers of Neutrophil Extracellular Traps. [PDF]

Inflammation
Bečka E, Hudecová L, Pastorek M.
europepmc   +1 more source

Leukotrienes: Bridging the Inflammatory Gap in Asthma and Inflammatory Bowel Diseases (IBD). [PDF]

Compr Physiol
Sabu Kattuman EE, Teegala LR, Darzi S, Thodeti CK, Paruchuri S.   +4 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Leukotriene B4 receptors

Prostaglandins & Other Lipid Mediators, 2002
Leukotriene B4 (LTB4) is a potent chemotactic agent and activating factor for granulocytes. Two cell surface receptors for LTB4 (BLT1 and BLT2) have been isolated in the last few years. These receptors are G-protein-coupled receptors (GPCR), and they have 45% amino acid identity. BLT1 and BLT2 are high- and low- affinity receptors, respectively.
Akiko, Toda, Takehiko, Yokomizo, Takao, Shimizu   +2 more
openaire   +2 more sources

-alkoxyphenol leukotriene B4 receptor antagonists

Bioorganic & Medicinal Chemistry Letters, 1992
Abstract A series of ortho -alkoxyphenols containing a tetrazole acid sidechain have been prepared as antagonists of leukotriene B4 receptors. These compounds were tested as receptor antagonists of human neutrophil and guinea pig lung membrane leukotriene B4 receptors.
Michael J. Sofia, William T. Jackson, Davis L. Saussy, Steven A. Silbaugh, Larry L. Froelich, Sandra L. Cockerham, Peter W. Stengel   +6 more
openaire   +1 more source

Leukotriene B3, leukotriene B4 and leukotriene B5; Binding to leukotriene B4 receptors on rat and human leukocyte membranes

Prostaglandins, 1986
Specific high-affinity binding sites for [3H]-leukotriene B4 have been identified on membrane preparations from rat and human leukocytes. The rat and human leukocyte membrane preparations show linearity of binding with increasing protein concentration, saturable binding and rapid dissociation of binding by excess unlabelled leukotriene B4. Dissociation
S, Charleson, J F, Evans, R J, Zamboni, Y, Leblanc, B J, Fitzsimmons, C, Leveillé, P, Dupuis, A W, Ford-Hutchinson   +7 more
openaire   +2 more sources

Leukotriene B4 Receptors

2015
Leukotriene B4 (LTB4) is a classical pro-inflammatory lipid mediator that activates and recruits neutrophils into inflammatory areas. LTB4 is an arachidonic acid-derived metabolite produced by 5-lipoxygenase and LTA4 hydrolase. To date, two leukotriene B4 receptors, the high-affinity receptor BLT1 and the low-affinity receptor BLT2, have been cloned ...
Tomoaki Koga, Takehiko Yokomizo
openaire   +1 more source

Leukotriene-B4 Receptor and Signal Transduction

2000
When cells are stimulated with various agonists, cells release arachidonic acid by the action of phospholipases, and arachidonic acid is further converted to various types of leukotrienes (LTs; Samuelsson et al. 1987; Shimizu and Wolfe 1990; Serhan et al. 1996).
T, Shimizu, T, Yokomizo, T, Izumi
openaire   +2 more sources

Assay for the leukotriene B4 receptor

1987
Publisher Summary This chapter discusses the binding assay in intact cells, membranes, and a detergent-solubilized preparation and a facile neutrophil aggregation assay that can be used to correlate binding data with biological information. The leukotrienes are metabolites of arachidonic acid whose potent biological activities suggest an important ...
R R, Gorman, A H, Lin
openaire   +2 more sources