Results 41 to 50 of about 17,556 (218)

Regulation of Immune Cells by Eicosanoid Receptors

The Scientific World Journal, 2007
Eicosanoids are potent, bioactive, lipid mediators that regulate important components of the immune response, including defense against infection, ischemia, and injury, as well as instigating and perpetuating autoimmune and inflammatory conditions ...
Nancy D. Kim, Andrew D. Luster
doaj   +1 more source

Leukotriene receptor expression in esophageal squamous cell cancer and non-transformed esophageal epithelium: a matched case control study [PDF]

, 2016
Study questionnaire.
C. Helmke, D. Jechorek, J. Weigt, K. Antweiler, M. Venerito, P. Malfertheiner, R. Rosania, T. Wex   +7 more
core   +2 more sources

Differential Contribution of BLT1 and BLT2 to Leukotriene B4-Induced Human NK Cell Cytotoxicity and Migration

Mediators of Inflammation, 2015
Accumulating evidence indicates that leukotriene B4 (LTB4) via its receptors BLT1 and/or BLT2 (BLTRs) could have an important role in regulating infection, tumour progression, inflammation, and autoimmune diseases.
Meng Wang, Nermine Mostafa El-Maghraby, Sylvie Turcotte, Marek Rola-Pleszczynski, Jana Stankova   +4 more
doaj   +1 more source

Purinergic Cooperation Between P2Y2 and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

Frontiers in Immunology, 2018
The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key component of innate immune response to infection.
Maria Luiza Thorstenberg, Marcos Vinícius Rangel Ferreira, Natália Amorim, Claudio Canetti, Fernanda B. Morrone, José Carlos Alves Filho, Robson Coutinho-Silva   +6 more
doaj   +1 more source

Lipid Mediators in Inflammation [PDF]

, 2016
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core   +1 more source

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1. [PDF]

PLoS ONE, 2017
Leukotriene B4 (LTB4) receptor 1 (BLT1) is a G protein-coupled receptor expressed in various leukocyte subsets; however, the precise expression of mouse BLT1 (mBLT1) has not been reported because a mBLT1 monoclonal antibody (mAb) has not been available ...
Fumiyuki Sasaki, Tomoaki Koga, Kazuko Saeki, Toshiaki Okuno, Saiko Kazuno, Tsutomu Fujimura, Yasuyuki Ohkawa, Takehiko Yokomizo   +7 more
doaj   +1 more source

Arachidonic acid and calcium metabolism in rnelittin stimulated neutrophils

Mediators of Inflammation, 1992
Melittin, the predominant fraction of bee venom proteins, was studied in an experimental model of human neutrophil granulocytes to reveal its influence on eicosanoid release, metabolism and receptor function in relation to intracellular calcium ...
Ole H. Nielsen, Pierre N. Bouchelouche, Dag Berild   +2 more
doaj   +1 more source

CD36 Shunts Eicosanoid Metabolism to Repress CD14 Licensed Interleukin-1β Release and Inflammation

Frontiers in Immunology, 2018
Interleukin (IL)-1β is a potential target for treatment of several inflammatory diseases, including envenomation by the scorpion Tityus serrulatus.
Karina F. Zoccal, Luiz G. Gardinassi, Carlos A. Sorgi, Alyne F. G. Meirelles, Karla C. F. Bordon, Isaias Glezer, Palmira Cupo, Alessandra K. Matsuno, Valdes R. Bollela, Eliane C. Arantes, Francisco S. Guimarães, Lúcia Helena Faccioli   +11 more
doaj   +1 more source

Phase 2 trial of montelukast for prevention of pain in sickle cell disease. [PDF]

, 2020
Cysteinyl leukotrienes (CysLTs) are lipid mediators of inflammation. In patients with sickle cell disease (SCD), levels of CysLTs are increased compared with controls and associated with a higher rate of hospitalization for pain. We tested the hypothesis
Brandow, Amanda, Bryant, Valencia, DeBaun, Michael R, Embury, Stephen H, Field, Joshua J, Kassim, Adetola, Matsui, Neil, Simpson, Pippa, Wilkerson, Karina, Zhang, Liyun   +9 more
core  

Cigarette smoke increases BLT2 receptor functions in bronchial epithelial cells: in vitro and ex vivo evidence [PDF]

, 2013
Leukotriene B4 (LTB4) is a neutrophil chemotactic molecule with important involvement in the inflammatory responses of chronic obstructive pulmonary disease (COPD).
Bruno, A., DI BENEDETTO, D., DI VINCENZO, S., Ferraro, M., Giarratano, A., Gjomarkaj, M., Lipari, L., Pace, E., Scafidi, V., Sciarrino, S.   +9 more
core   +1 more source