Results 11 to 20 of about 538,837 (164)

Neurotensin receptors in pancreatic ductal carcinomas. [PDF]

open access: yesEJNMMI Research, 2015
BACKGROUND The frequent expression of neurotensin receptors (NT-R) in primaries of pancreatic ductal carcinomas has triggered the development of radioactive neurotensin analogs for possible in vivo targeting of these tumors. However, the complete lack
Strobel, Oliver   +9 more
core   +7 more sources

Neurotensin and its receptors in the control of glucose homeostasis [PDF]

open access: yesFrontiers in Endocrinology, 2012
The pharmacological roles of the neuropeptide neurotensin through its three known receptors are various and complex. Neurotensin is involved in several important biological functions including analgesia and hypothermia in the central nervous system and ...
Jean eMazella   +4 more
doaj   +2 more sources

Neurotensin receptors in human meningiomas

open access: yesAnnals of Neurology, 1991
We have investigated the presence of neurotensin receptors in human meningiomas by in vitro binding autoradiography. Ten of the 12 meningiomas tested displayed specific [3H}neurotensin binding.
Levivier, M.   +5 more
core   +4 more sources

CB1 cannabinoid receptors are involved in neuroleptic-induced enhancement of brain neurotensin [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2014
Objective(s): Targeting the neuropeptide systems has been shown to be useful for the development of more effective antipsychotic drugs. Neurotensin, an endogenous neuropeptide, appears to be involved in the mechanism of action of antipsychotics. However,
Parichehr Hassanzadeh, Fatemeh Rostami
doaj   +1 more source

Internalization and recycling properties of neurotensin receptors.

open access: yesPeptides, 2006
The targeting, internalization and recycling of membrane receptors in response to extracellular ligands involve a series of molecular mechanisms which are beginning to be better understood.
Vincent, Jean-Pierre, Mazella, Jean
core   +3 more sources

Endogenous CNS expression of neurotensin and neurotensin receptors is altered during the postpartum period in outbred mice. [PDF]

open access: yesPLoS ONE, 2014
Neurotensin (NT) is a neuropeptide identical in mice and humans that is produced and released in many CNS regions associated with maternal behavior.
Terri M Driessen   +4 more
doaj   +2 more sources

Activation of B2 bradykinin receptors by neurotensin

open access: yesCellular Signalling, 2019
Many previous reports suggested that relatively high concentrations of neurotensin were required to exert its effects on neurotransmitter secretion. The neurotensin binding sites, which recognize high concentrations of neurotensin, were characterized in ...
Kim, KT, Park, TJ
core   +4 more sources

Neurotensin Regulates Primate Ovulation Via Multiple Neurotensin Receptors [PDF]

open access: yesEndocrinology
Neurotensin (NTS), a small neuropeptide, was recently established as a key paracrine mediator of ovulation. NTS mRNA is highly expressed by granulosa cells in response to the luteinizing hormone (LH) surge, and multiple NTS receptors are expressed by ...
Duffy, Diane M.   +5 more
core   +3 more sources

Neurotensin receptors as modulators of glutamatergic transmission

open access: yesBrain Research Reviews, 2008
Functional studies have provided evidence supporting the concept that the tridecapeptide neurotensin (NT) acts in the central nervous system as a classical neurotransmitter and/or as an important modulator of neuronal signalling.
FERRARO, Luca Nicola   +13 more
core   +4 more sources

Neurotensin receptors in GtoPdb v.2023.1 [PDF]

open access: yes, 2023
Neurotensin receptors (nomenclature as recommended by NC-IUPHAR [39]) are activated by the endogenous tridecapeptide neurotensin (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu) derived from a precursor (NTS, 30990), which also generates neuromedin
Philippe Sarret   +5 more
core   +1 more source

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