Results 81 to 90 of about 538,837 (164)

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, Volume 604, Issue 11, Page 4338-4377, 1 June 2026.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Down-regulation of neurotensin receptors after ligand-induced internalization in rat primary cultured neurons

, 1997
When rat cultured neurons were incubated with unlabelled neurotensin (3 nM) for 1 or 24 h at 37 degrees C, the [3H]-neurotensin specific binding measured in cell homogenates was decreased to about 35 and 65% of control values, respectively.
Maloteaux, Jean-Marie, Hermans, Emmanuel, Vanisberg, Marie-Agnès, Geurts, Muriel   +3 more
core   +1 more source

Complementarity of radioautographic and immunohistochemical techniques for localizing neuroreceptors at the light and electron microscopy level

Brazilian Journal of Medical and Biological Research, 1998
To assess relationships between neuropeptide-binding sites and receptor proteins in rat brain, the distribution of radioautographically labeled somatostatin and neurotensin-binding sites was compared to that of immunolabeled sst2A and NTRH receptor ...
Beaudet A.
doaj  

New Insights in the Design of Bioactive Peptides and Chelating Agents for Imaging and Therapy in Oncology

Molecules, 2017
Many synthetic peptides have been developed for diagnosis and therapy of human cancers based on their ability to target specific receptors on cancer cell surface or to penetrate the cell membrane.
Anna Lucia Tornesello, Luigi Buonaguro, Maria Lina Tornesello, Franco Maria Buonaguro   +3 more
doaj   +1 more source

Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications

Biomolecules, 2020
Introduction: Colorectal Cancer (CRC) accounts for 9% of cancer deaths globally. Hormonal pathways play important roles in some cancers. This study investigated the association of CRC expression of neurotensin (NTS), NTS receptors 1 and 3 (NTSR1 and ...
Shengyang Qiu, Stella Nikolaou, Jie Zhu, Peter Jeffery, Robert Goldin, James Kinross, James L. Alexander, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios   +9 more
doaj   +1 more source

Differential Expression of Neurotensin and Specific Receptors, NTSR1 and NTSR2, in Normal and Malignant Human B Lymphocytes

, 2012
International audienceNeurotensin, a neuropeptide growth factor, and its two specific neurotensin receptors, NTSR1 and NTSR2, were shown to be expressed by human B cell lines.
Fauchais, A., Lise, C., Lise, Marie-Claude, Delpy, L., Vidal, E., Jaccard, Arnaud, Saada, S., Delpy, Laurent, Lalloue, F., Lalloué, Fabrice, Marget, P., Jauberteau, Marie-Odile, Saada, Sofiane, Troutaud, D., Vidal, Elisabeth, Martel, C., Sindou, P., Fauchais, Anne-Laure, Chemin, Guillaume, Martel, Clothilde, Jaccard, A., Marget, Pierre, Sindou, Philippe, Jauberteau, M.-O., Troutaud, Danielle, Chemin, G.   +25 more
core   +1 more source

Differential Effects of Neurotensin NTS1 and NTS2 Receptors on Locomotion

Brain and Behavior
Introduction Neurotensin (NT) is an endogenous neuropeptide with diverse central and peripheral effects, particularly as related to modulation of central nervous system dopaminergic activity.
Misty D. Smith, Elizabeth Jill Dahle, Annette E. Fleckenstein, Glen R. Hanson   +3 more
doaj   +1 more source

Characterisation of a cell-free synthesised G-protein coupled receptor

Scientific Reports, 2017
G-protein coupled receptors are the largest family of integral membrane proteins found within the human genome. They function as receptors and modulators to a wide range of ligands and responses which are crucial for human health.
Patrick J. Shilling, Fabian Bumbak, Daniel J. Scott, Ross A. D. Bathgate, Paul R. Gooley   +4 more
doaj   +1 more source

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas

Molecular Metabolism, 2018
Objective: Bile acids (BAs) facilitate fat absorption and may play a role in glucose and metabolism regulation, stimulating the secretion of gut hormones.
Rune E. Kuhre, Nicolai J. Wewer Albrechtsen, Olav Larsen, Sara L. Jepsen, Emilie Balk-Møller, Daniel B. Andersen, Carolyn F. Deacon, Kristina Schoonjans, Frank Reimann, Fiona M. Gribble, Reidar Albrechtsen, Bolette Hartmann, Mette M. Rosenkilde, Jens J. Holst   +13 more
doaj   +1 more source

Postnatal ontogeny of the rat brain neurotensin receptor mRNA.

, 1993
Total RNA was purified from rat forebrain at different postnatal ages and analyzed by Northern blot using a specific neurotensin receptor RNA probe. The rat neurotensin receptor mRNA was present in high amount during the first 10 days of life. Thereafter,
Maloteaux, Jean-Marie, Hermans, Emmanuel, Octave, Jean-Noël, Laduron, P M, Jeanjean, Anne   +4 more
core   +1 more source