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Anti-Viral Pattern Recognition Receptors as Therapeutic Targets
Pattern recognition receptors (PRRs) play a central role in the inflammation that ensues following microbial infection by their recognition of molecular patterns present in invading microorganisms but also following tissue damage by recognising molecules
Conor Hennessy, Declan P. McKernan
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Pattern recognition receptors in health and diseases
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged senescent cells.
Danyang Li, Minghua Wu
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Pattern-recognition receptors in endometriosis: A narrative review
Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-associated ...
Bao Guo +7 more
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Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn +3 more
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Intracellular PRRs Activation in Targeting the Immune Response Against Fungal Infections
The immune response against fungal infections is complex and exhibits several factors involving innate elements that participate in the interaction with the fungus. The innate immune system developed pattern recognition receptors that recognize different
Grasielle Pereira Jannuzzi +4 more
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Immune functions of pattern recognition receptors in Lepidoptera
Pattern recognition receptors (PRRs), as the “sensors” in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera.
Lin Zhao +4 more
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Reducing inflammation by diet is a major goal for prevention or lowering symptoms of a variety of diseases, such as auto-immune reactions and cancers.
Lucas de Freitas Pedrosa +2 more
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Pattern recognition receptors and autophagy
The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
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Pattern recognition receptors and gastric cancer
Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez +2 more
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Pattern recognition receptors in HIV transmission
Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
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