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Purinergic receptors in auditory neurotransmission
Hearing Research, 2003The effects of ATP (adenosine 5' triphosphate) analogs on gross cochlear potentials and single primary afferent discharge properties were studied by intracochlear perfusion in anesthetized guinea pigs. ATP-gamma-S was most potent, with betagammamethylene-ATP and Bz-ATP being significantly less effective.
Bardia Paki +3 more
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Purinergic receptors in psychiatric disorders
Neuropharmacology, 2016Psychiatric disorders describe different mental or behavioral patterns, causing suffering or poor coping of ordinary life with manifold presentations. Multifactorial processes can contribute to their development and progression. Purinergic neurotransmission and neuromodulation in the brain have attracted increasing therapeutic interest in the field of ...
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The enteric purinergic P2Y1 receptor
Current Opinion in Pharmacology, 2006Significant recent discoveries have shown that the P2Y(1) purinergic receptor subtype is expressed in the enteric nervous system and at intestinal neuromuscular junctions. Secretomotor neurons, which release vasoactive intestinal peptide at their junctions with intestinal secretory glands, express the P2Y(1) receptor.
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Purinergic receptors in embryonic and adult neurogenesis
Neuropharmacology, 2016ATP (adenosine 5'-triphosphate), one of the most ancient neurotransmitters, exerts essential functions in the brain, including neurotransmission and modulation of synaptic activity. Moreover, this nucleotide has been attributed with trophic properties and experimental evidence points to the participation of ATP-activated P2X and P2Y purinergic ...
Ágatha Oliveira +2 more
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Pathological Potential of Astroglial Purinergic Receptors
2014Acute brain injury and neurodegenerative disorders may result in astroglial activation. Astrocytes are able to determine the progression and outcome of these neuropathologies in a beneficial or detrimental way. Nucleotides, e.g. adenosine 5'-triphosphate (ATP), released after acute or chronic neuronal injury, are important mediators of glial activation
Heike Franke, Peter Illes
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Is the benzodiazepine receptor purinergic?
European Journal of Pharmacology, 1979H.W. Damm +2 more
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Purinergic Receptors and Hepatobiliary Function
2003Publisher Summary This chapter describes the basic mechanisms that contribute to purinergic signaling in liver cells by focusing on a molecular and pharmacologic description of the receptors present, the mechanisms and regulation of adenosine triphosphate (ATP) release, and nucleotide/nucleoside degradation and reuptake pathways.
Andrew P. Feranchak, J. Gregory Fitz
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Purinergic signaling in peripheral nervous system glial cells
Glia, 2021Jennifer Patritti-cram +2 more
exaly
From purines to purinergic signalling: molecular functions and human diseases
Signal Transduction and Targeted Therapy, 2021Alexei Verkhratsky +2 more
exaly