Expression and distribution of ectonucleotidases in mouse urinary bladder.
PLoS ONE, 2011 BackgroundNormal urinary bladder function requires bidirectional molecular communication between urothelium, detrusor smooth muscle and sensory neurons and one of the key mediators involved in this intercellular signaling is ATP.
Weiqun Yu, Simon C Robson, Warren G Hill
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The role of purinergic receptors in stem cell differentiation
Computational and Structural Biotechnology Journal, 2015 A major challenge modern society has to face is the increasing need for tissue regeneration due to degenerative diseases or tumors, but also accidents or warlike conflicts.
Constanze Kaebisch +3 more
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The actions of Pasteurella multocida toxin on neuronal cells [PDF]
, 2014 Pasteurella multocida toxin (PMT) activates the G-proteins Gα, Gα, Gα Gα and Gα by deamidation of specific glutamine residues. A number of these alpha subunits have signalling roles in neurones.
Duricki, DA +4 more
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Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]
, 2000 Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
Burnstock, G +5 more
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Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity
Frontiers in Pharmacology, 2018 Adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+) are released as danger signals from cells during infection and sterile inflammation.
Stephan Menzel +3 more
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Differences in localization of P2X7 during epithelial wound healing in pre-type II diabetic models [PDF]
, 2017 Corneal injury, accompanied by improper wound repair, is the 4th highest cause of preventable blindness according to the World Health Organization.
Kneer, Krisandra
core
The role of dinucleoside polyphosphates on the ocular surface and other eye structures [PDF]
, 2016 Dinucleoside polyphosphates comprises a group of dinucleotides formed by two nucleosides linked by a variable number of phosphates, abbreviated NpnN (where n represents the number of phosphates). These compounds are naturally occurring substances present
Carracedo Rodríguez, Juan Gonzalo +3 more
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Frontiers in Pharmacology, 2018 Plasma levels of the vasoactive substance uridine adenosine tetraphosphate (Up4A) are elevated in hypertensive patients and Up4A-induced vascular contraction is exacerbated in various arteries isolated from hypertensive animals, suggesting a potential ...
Zhichao Zhou +13 more
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Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists. [PDF]
, 1998 Novel analogs of the P2 receptor antagonist pyridoxal-5'-phosphate-6-phenylazo-2',4'-disulfonate (PPADS) were synthesized. Modifications were made through functional group substitution on the sulfophenyl ring and at the phosphate moiety through the ...
Boyer, José L. +13 more
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Adenosine: Direct and Indirect Actions on Gastric Acid Secretion
Frontiers in Physiology, 2017 Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the metabolic and regulatory contexts.
Rosa M. Arin +5 more
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