Results 101 to 110 of about 14,791 (200)
New Phytologist, Volume 248, Issue 5, Page 2192-2197, December 2025.
Youzheng Ning +9 more
wiley +1 more source
Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]
Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Dale, Nicholas, Wall, Mark J.
core +2 more sources
An emerging role for adenosine and its receptors in bone homeostasis
Bone is continually being remodelled and defects in the processes involved lead to bone diseases. Many regulatory factors are known to influence remodelling but other mechanisms, hitherto unknown, may also be involved.
Bronwen eEvans +3 more
doaj +1 more source
P2X7 receptors induce degranulation in human mast cells. [PDF]
Mast cells play important roles in host defence against pathogens, as well as being a key effector cell in diseases with an allergic basis such as asthma and an increasing list of other chronic inflammatory conditions.
A Lundequist +43 more
core +1 more source
Extracellular ATP is a potent signaling molecule that stimulates intracellular calcium responses through purinergic (P2) receptors in mammalian cells. While extracellular ATP and intracellular calcium can be measured separately, simultaneous monitoring ...
Nicholas Mikolajewicz, Svetlana Komarova
doaj +1 more source
Differences in localization of P2X7 during epithelial wound healing in pre-type II diabetic models [PDF]
Corneal injury, accompanied by improper wound repair, is the 4th highest cause of preventable blindness according to the World Health Organization.
Kneer, Krisandra
core
Functional maturation of isolated neural progenitor cells from the adult rat hippocampus [PDF]
Although neural progenitor cells (NPCs) may provide a source of new neurons to alleviate neural trauma, little is known about their electrical properties as they differentiate.
Chipperfield H. +15 more
core +1 more source
Organs and tissues and their constituent cells are physiologically submitted to diverse types of mechanical forces or stress, one common sequence of which is release of intracellular ATP into extracellular space.
Linyu Wei +8 more
doaj +1 more source
P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development
Extracellular nucleotides like ATP bind to cell surface receptors (P2 purinergic receptors) in many tissues. P2X receptor subtypes are intrinsic ion channels that mediate depolarization and influx of Ca2+, whereas the P2Y receptor subtypes couple through G proteins to activation of phospholipase Cβ and mobilization of intracellular Ca2+. In nonskeletal
Dixon, S. Jeffrey, Sims, Stephen M.
openaire +2 more sources
Modulation of Phagocytosis by P2-Purinergic Receptors in Mouse Peritoneal Macrophages.
The effects of adenosine 5'-triphosphate (ATP) and other nucleotides on phagocytosis of peritoneal macrophages were examined by means of flow cytometry (FCM). ATP and uridine 5'-triphosphate (UTP) enhanced phagocytosis in a dose-dependent manner. Control phagocytosis was partially suppressed in Ca(2+)-free solution.
openaire +3 more sources

