Results 111 to 120 of about 28,114 (251)

Modulation of Phagocytosis by P2-Purinergic Receptors in Mouse Peritoneal Macrophages.

open access: yesThe Japanese Journal of Physiology, 1995
The effects of adenosine 5'-triphosphate (ATP) and other nucleotides on phagocytosis of peritoneal macrophages were examined by means of flow cytometry (FCM). ATP and uridine 5'-triphosphate (UTP) enhanced phagocytosis in a dose-dependent manner. Control phagocytosis was partially suppressed in Ca(2+)-free solution.
openaire   +3 more sources

Purinergic receptor expression in neuronal, bladder smooth muscle and urothelial cells: characterization and inhibition by low molecular weight antagonists

open access: yes, 2009
P2 purinoceptors comprise ionotropic (P2X) and metabotropic (P2Y) receptor families, responsive to nucleotide ligands and diversely distributed on virtually every mammalian cell. Most cells and tissues co-express multiple subtypes of purinoceptor; thus,
Gever, J.L.
core  

Labeling and tracking P2 purinergic receptors in living cells using ATP-conjugated quantum dots

open access: yes, 2011
It has been increasingly recognized that adenosine-5 ′ -triphosphate (ATP) signaling through P2 purinergic receptors has a diverse infl uence on cell functions and human health.
Soo, Jianchow   +9 more
core   +1 more source

Extracellular ATP and Cancer—An Overview with Special Reference to P2 Purinergic Receptors

open access: yesPathology & Oncology Research, 2008
Purinergic signal transduction mechanisms have been appreciated as a complex intercellular signalling network that plays an important regulatory role in both short- and long-term processes in practically every living cell. One of the most intriguing aspects of the field is the participation of ATP and other purine nucleotides in the determination of ...
Tamás, Deli, László, Csernoch
openaire   +2 more sources

P2 receptors and immunity

open access: yes, 2012
Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on
DI VIRGILIO, Francesco   +2 more
core   +1 more source

An emerging role for adenosine and its receptors in bone homeostasis

open access: yesFrontiers in Endocrinology, 2012
Bone is continually being remodelled and defects in the processes involved lead to bone diseases. Many regulatory factors are known to influence remodelling but other mechanisms, hitherto unknown, may also be involved.
Bronwen eEvans   +3 more
doaj   +1 more source

Adenosine Triphosphate Release and P2 Receptor Signaling in Piezo1 Channel-Dependent Mechanoregulation

open access: yesFrontiers in Pharmacology, 2019
Organs and tissues and their constituent cells are physiologically submitted to diverse types of mechanical forces or stress, one common sequence of which is release of intracellular ATP into extracellular space.
Linyu Wei   +8 more
doaj   +1 more source

The P2X receptor mediated regulation of inhibitory synaptic transmission [PDF]

open access: yes
In the central nervous system ATP can be released by neurons and glial cells through similar pathways as other neurotransmitters. Extracellular ATP targets P2X purinoreceptors, causing an influx of Ca2+ ions which transmit very important messages for ...
Andrew-Adiamah, Jemma
core  

P2 purinergic receptors and cellular calcium metabolism in A 431 human epidermoid carcinoma cells

open access: yes, 1992
Stimulation of P2 purinergic receptors on A 431 human epidermoid cells with ATP rapidly mobilized intracellular calcium and increased cytosolic free Ca2+ ([Ca2+]i).
T. Atsumi   +6 more
core   +1 more source

Simultaneous Fluorescent Recordings of Extracellular ATP and Intracellular Calcium in Mammalian Cells

open access: yesBio-Protocol, 2019
Extracellular ATP is a potent signaling molecule that stimulates intracellular calcium responses through purinergic (P2) receptors in mammalian cells. While extracellular ATP and intracellular calcium can be measured separately, simultaneous monitoring ...
Nicholas Mikolajewicz, Svetlana Komarova
doaj   +1 more source

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