Results 111 to 120 of about 28,974 (217)
Purinergic Signaling and Dental Orofacial Pain [PDF]
, 2019 Pain is a common complaint of patients in the dental clinic. Patient with dental orofacial pain usually presents with hyperalgesia and allodynia.
Liu, Xiuxin
core +2 more sources
An emerging role for adenosine and its receptors in bone homeostasis
Frontiers in Endocrinology, 2012 Bone is continually being remodelled and defects in the processes involved lead to bone diseases. Many regulatory factors are known to influence remodelling but other mechanisms, hitherto unknown, may also be involved.
Bronwen eEvans +3 more
doaj +1 more source
Purinergic mechanisms in neuroinflammation: An update from molecules to behavior. [PDF]
, 2015 The principle functions of neuroinflammation are to limit tissue damage and promote tissue repair in response to pathogens or injury. While neuroinflammation has utility, pathophysiological inflammatory responses, to some extent, underlie almost all ...
Beamer, Edward +6 more
core +1 more source
Frontiers in Pharmacology, 2019 Organs and tissues and their constituent cells are physiologically submitted to diverse types of mechanical forces or stress, one common sequence of which is release of intracellular ATP into extracellular space.
Linyu Wei +8 more
doaj +1 more source
Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement [PDF]
, 2017 We previously demonstrated that uridine adenosine tetraphosphate (Up4A) induces potent and partially endothelium-dependent relaxation in the healthy porcine coronary microvasculature.
Beer, V.J. (Vincent Jacob) de +7 more
core +2 more sources
The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?
Frontiers in Pharmacology, 2018 Under physiological conditions, adenosine triphosphate (ATP) is present at low levels in the extracellular milieu, being massively released by stressed or dying cells.
Luiz E. B. Savio +3 more
doaj +1 more source
Purine and purinergic receptors
Brain and Neuroscience Advances, 2018 Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors have been cloned and characterised. P1 receptors are selective for adenosine, a
G. Burnstock
semanticscholar +1 more source
Action of Natural Products on P2 Receptors: A Reinvented Era for Drug Discovery
Molecules, 2012 Natural products contribute significantly to available drug therapies and have been a rich source for scientific investigation. In general, due to their low cost and traditional use in some cultures, they are an object of growing interest as alternatives
Luiz Alves +4 more
doaj +1 more source
Antidipsogenic effects of central adenosine-5'-triphosphate
Brazilian Journal of Medical and Biological Research, 2009 Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect ...
D.R.G. de Faria +3 more
doaj