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Purinergic Regulation of Neutrophil Function
Purinergic signaling, which utilizes nucleotides (particularly ATP) and adenosine as transmitter molecules, plays an essential role in immune system. In the extracellular compartment, ATP predominantly functions as a pro-inflammatory molecule through ...
Xu Wang
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Purinergic Signaling in Liver Pathophysiology
Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP.
Shanu Jain, Kenneth A Jacobson
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Extracellular ATP, related nucleotides and adenosine are among the earliest signaling molecules, operating in virtually all tissues and cells. Through their specific receptors, namely purinergic P1 for nucleosides and P2 for nucleotides, they are ...
Fabio Cavaliere, Nadia D'ambrosi
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Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides.
American Journal of Physiology, 1993Extracellular ATP, at micromolar concentrations, induces significant functional changes in a wide variety of cells and tissues. ATP can be released from the cytosol of damaged cells or from exocytotic vesicles and/or granules contained in many types of ...
G. Dubyak, Chakib El-Moatassim
semanticscholar +1 more source
International Reviews of Immunology, 2020
The nucleotide adenosine-5′-triphosphate (ATP) is mostly thought to be energy carrier, but evidence presented in multiple studies proves ATP involvement into variety of processes, due to its neuromodulatory capabilities. ATP and its metabolite—adenosine,
Marharyta Zyma, R. Pawliczak
semanticscholar +1 more source
The nucleotide adenosine-5′-triphosphate (ATP) is mostly thought to be energy carrier, but evidence presented in multiple studies proves ATP involvement into variety of processes, due to its neuromodulatory capabilities. ATP and its metabolite—adenosine,
Marharyta Zyma, R. Pawliczak
semanticscholar +1 more source
P2 purinergic receptors regulate the progression of colorectal cancer.
Purinergic Signalling Purinergic Signalling, 2023Wen-jun Zhang+4 more
semanticscholar +1 more source
Current pharmaceutical design, 2007
Micturition, penile erection, contraction of prostatic smooth muscle, peristalsis of the male excurrent duct system and lumbosacral spinal cord neurotransmission all require adenosine 5'-triphosphate (ATP) activity and this likely involves purinergic (P2)
S. Gur, P. Kadowitz, W. Hellstrom
semanticscholar +1 more source
Micturition, penile erection, contraction of prostatic smooth muscle, peristalsis of the male excurrent duct system and lumbosacral spinal cord neurotransmission all require adenosine 5'-triphosphate (ATP) activity and this likely involves purinergic (P2)
S. Gur, P. Kadowitz, W. Hellstrom
semanticscholar +1 more source
Purinergic signaling in peripheral nervous system glial cells
Glia, 2021Jennifer Patritti-cram+2 more
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