Results 91 to 100 of about 13,842 (161)
Catheterization and Cardiovascular Interventions, Volume 106, Issue 5, Page 2805-2815, November 1, 2025.ABSTRACT Background Mortality in patients with cardiogenic shock (CS) remains high despite advanced treatment strategies in CS patients, underlining the need for the identification of predictors of prognosis in CS patients. Therefore, the present study investigates the prognostic impact of coronary chronic total occlusions (CTO) in patients with CS ...
Michael Behnes +15 more
wiley +1 more source
Frontiers in Endocrinology, 2012 Purinergic signalling in bone was first proposed in the early 1990s with the observation that extracellular ATP could modulate events crucial to the normal functioning of bone cells.
Robin Mark Howard Rumney +3 more
doaj +1 more source
Transcriptional and translational differences of microglia from male and female brains [PDF]
, 2019 Sex differences in brain structure and function are of substantial scientific interest because of sex-related susceptibility to psychiatric and neurological disorders. Neuroinflammation is a common denominator of many of these diseases and thus microglia
Güneykaya, Dilansu
core +1 more source
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
Glia, Volume 73, Issue 11, Page 2154-2166, November 2025.Main Points Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols.
Xabier Cuesta‐Puente +8 more
wiley +1 more source
P2Y2 receptor knock-out mice display normal NaCl absorption in medullary thick ascending limb
Frontiers in Physiology, 2013 Local purinergic signals modulate renal tubular transport. Acute activation of renal epithelial P2 receptors causes inhibition of epithelial transport and thus, should favor increased water and salt excretion by the kidney. So far only a few studies have
Rita Delgado Marques +2 more
doaj +1 more source
Resetting intrinsic purinergic modulation of neural activity: an associative mechanism? [PDF]
, 2002 The purines, ATP and adenosine, control the rundown and termination of swimming in the Xenopus embryo. This intrinsic purinergic modulation, unavoidably present during every swimming episode, could lead to stereotyped inflexible behavior and consequently
Dale, Nicholas
core +1 more source
Journal of Neurochemistry, Volume 169, Issue 11, November 2025.In this review, we discuss the development and maturation of inhibitory neurons and astrocytes and how early developmental activity in the brain might promote the interactions between these cell types. Early in development, excitatory neurons are the first to emerge.
Niina Lehti Tauriala, Vered Kellner
wiley +1 more source
Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes [PDF]
, 2018 White adipocytes are key regulators of metabolic homeostasis, which release stored energy as free fatty acids via lipolysis. Adipocytes possess both basal and stimulated lipolytic capacity, but limited information exists regarding the molecular ...
Ahmadian +62 more
core +1 more source
Physiological Electrical Signals Promote Chain Migration of Neuroblasts by Up-Regulating P2Y1 Purinergic Receptors and Enhancing Cell Adhesion [PDF]
, 2014 Acknowledgments This work was supported by a grant from NHS Grampian. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the ...
Cao, Lin +4 more
core +2 more sources
The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy
Frontiers in Pharmacology, 2018 Epilepsy encompasses a heterogeneous group of neurological syndromes which are characterized by recurrent seizures affecting over 60 million people worldwide.
Mariana Alves +2 more
doaj +1 more source