Expression of purinergic P2 receptors and their role in intracellular calcium signaling of neonatal pituitary cells [PDF]
, 2014 This diploma thesis focuses on study of the expression of purinergic receptors P2X and P2Y in the cells of neonatal adenohypofysis. Purinergic receptors are activated by binding of extracellular ATP and their activation leads to an increase in ...
Šprláková, Katarína
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Na+ absorption by Claudius’ cells is regulated by purinergic signaling in the cochlea
, 2012 Conclusion: Claudius’ cells absorb Na+ through the amiloride-sensitive epithelial sodium channel (ENaC). Transepithelial ion transport through ENaC and possibly a Cl[superscript]- secretory pathway is regulated by P2Y purinergic signaling.
Han, Kyu-Hee +6 more
core +1 more source
P2Y2- and P2Y4 purinergic receptors are over-expressed in human colon cancer
, 2007 1. A characteristic of cancer is altered signal transduction leading to uninhibited growth. Adenosine-5'-triphosphate (ATP), a natural ligand at P2X- and P2Y purinergic receptors may regulate cell growth in non-neoplastic, as well as neoplastic tissues ...
Hultman, L. +3 more
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The Role of Purinergic Receptors in Retinal Function and Disease
Extracellular ATP acts as a neurotransmitter in the central and peripheral nervous systems. In this review, the role of purinergic receptors in neuronal signaling and bidirectional glial-neuronal communication in the retina will be considered.
Puthussery, Theresa +3 more
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Damage-induced signalling mechanisms in the neonatal rat cochlea.
, 2007 Sound overstimulation and exposure to ototoxic drugs damage cochlear hair cells (HCs) and cause their death. The surrounding support cells maintain an epithelial barrier and the appropriate physiological environment for surviving HCs during pathological ...
Lahne, M.
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Rapid resensitization of purinergic receptor function in human platelets
, 2008 BACKGROUND: Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors (GPCRs), the P2Y(1) and P2Y(12) purinergic receptors.
Barton, JF +4 more
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P2RY8 (purinergic receptor P2Y, G-protein coupled, 8) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017 Mackarel, Jill +2 more
openaire +2 more sources
P2Y2 Purinergic Receptor Promotes Trafficking of Hematopoietic Stem/Progenitor Cells (HSPCs). [PDF]
Stem Cell Rev RepAdamiak M +6 more
europepmc +1 more source
Activation of purinergic P2X receptors inhibits P2Y-mediated Ca2+ influx in human microglia.
, 2000 Purinoceptor (P2X and P2Y) mediated Ca2+ signaling in cultured human microglia was studied using Ca2+ sensitive fluorescence microscopy. ATP (at 100 microM) induced a transient increase in [Ca2+]i in both normal and Ca(2+)-free solution suggesting a ...
Wang, X +3 more
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Host-directed therapeutic strategies against apicomplexan parasites: targeting purinergic P2 receptors. [PDF]
Purinergic SignalChaves MM +3 more
europepmc +1 more source