Results 11 to 20 of about 729,299 (226)

PLAUR (plasminogen activator, urokinase receptor) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on PLAUR (plasminogen activator, urokinase receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Jacobsen, B, Illemann, M, Ploug, M
openaire   +4 more sources

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

open access: yesInternational Journal of Dental Hygiene
ABSTRACTIntroductionThe plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur   +6 more
openaire   +4 more sources

Expression of urokinase plasminogen activator and the urokinase plasminogen activator receptor in myeloma cells [PDF]

open access: yesBritish Journal of Haematology, 2000
Binding of urokinase (uPA) to its receptor (uPAR; CD87) focuses proteolytic activity on the cell surface and this system is of importance in malignant matrix degradation and tumour invasion. By immunocytochemistry and flow cytometry, we found that primary myeloma cells and myeloma cell lines expressed uPA and uPAR.
O, Hjertner   +8 more
openaire   +2 more sources

The study of molecular markers for the progression of Barrett's Oesophagus to adenocarcinoma to identify markers that can be used as diagnostic tools. [PDF]

open access: yes, 2002
Barrett's oesophagus is a complication of gastro-oesophageal reflux disease and is the single most important predisposing factor for the development of adenocarcinoma of the oesophagus.
Cadd, Verity Anne
core   +4 more sources

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

open access: yesHepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou   +15 more
wiley   +1 more source

In Vitro Study of the Fibrinolytic Activity via Single Chain Urokinase-Type Plasminogen Activator and Molecular Docking of FGFC1

open access: yesMolecules, 2021
Fungi fibrinolytic compound 1 (FGFC1) is a rare marine-derived compound that can enhance fibrinolysis both in vitro and in vivo. The fibrinolytic activity characterization of FGFC1 mediated by plasminogen (Glu-/Lys-) and a single-chain urokinase-type ...
Chunli Gao   +8 more
doaj   +1 more source

Determining biomarkers for evaluation and diagnosis of hereditary angioedema

open access: yesClinical and Translational Allergy, 2022
Rationale Kallikrein‐bradykinin‐forming cascade is known to cause hereditary angioedema (HAE) acute angioedema (AE) attacks. Further research of HAE attacks is needed to explain disease heterogeneity, predict treatment response and identify biomarkers ...
Umesh Singh, Jonathan A. Bernstein
doaj   +1 more source

A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal   +5 more
doaj   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Soluble urokinase plasminogen activator receptor: a novel biomarker of pediatric community-acquired and hospitalacquired pneumonia

open access: yesThe Turkish Journal of Pediatrics, 2022
Background. Soluble urokinase plasminogen activator receptor (suPAR) is an emerging biomarker in different clinical disorders but data in pediatric pneumonia is scarce.
Muhammad Said El-Mekkawy   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy