Results 21 to 30 of about 14,304 (250)
Integrin, Exosome and Kidney Disease
Frontiers in Physiology, 2021 Integrins are transmembrane receptors that function as noncovalent heterodimers that mediate cellular adhesion and migration, cell to cell communication, and intracellular signaling activation.
An-Ran Shen +6 more
doaj +1 more source
Hepatology, EarlyView., 2022 KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
BMC Oral Health, 2022 Background Gingivitis is a reversible condition; however, if left untreated, it progresses to periodontitis, which a serious infection that leads to bone destruction.
Mohamed Abd‑Ellatif El‑Patal +7 more
doaj +1 more source
Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View
Frontiers in Cell and Developmental Biology, 2022 Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum ...
Daniela Alfano +2 more
doaj +1 more source
Function of hepatocyte growth factor in gastric cancer proliferation and invasion [PDF]
Yeungnam University Journal of Medicine, 2020 Cancer incidence has been increasing steadily and is the leading cause of mortality worldwide. Gastric cancer is still most common malignancy in Korea. Cancer initiation and progression are multistep processes involving various growth factors and their ...
Sung Ae Koh, Kyung Hee Lee
doaj +1 more source
PLAUR (plasminogen activator, urokinase receptor) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on PLAUR (plasminogen activator, urokinase receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Jacobsen, B, Illemann, M, Ploug, M
openaire +2 more sources
In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans. [PDF]
PLoS ONE, 2010 BACKGROUND: Leptospirosis is a multisystem disease caused by pathogenic strains of the genus Leptospira. We have reported that Leptospira are able to bind plasminogen (PLG), to generate active plasmin in the presence of activator, and to degrade purified
Monica L Vieira +6 more
doaj +1 more source
Determining biomarkers for evaluation and diagnosis of hereditary angioedema
Clinical and Translational Allergy, 2022 Rationale Kallikrein‐bradykinin‐forming cascade is known to cause hereditary angioedema (HAE) acute angioedema (AE) attacks. Further research of HAE attacks is needed to explain disease heterogeneity, predict treatment response and identify biomarkers ...
Umesh Singh, Jonathan A. Bernstein
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2000 The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal +5 more
doaj +1 more source
The Turkish Journal of Pediatrics, 2022 Background. Soluble urokinase plasminogen activator receptor (suPAR) is an emerging biomarker in different clinical disorders but data in pediatric pneumonia is scarce.
Muhammad Said El-Mekkawy +2 more
doaj +1 more source