Results 101 to 110 of about 2,306,220 (297)

Reference materials (RMs) for analysis of the human factor II (prothrombin) gene G20210A mutation [PDF]

, 2005
The Scientific Committee of Molecular Biology Techniques (C-MbT) in Clinical Chemistry of the IFCC has initiated a joint project in co-operation with the European Commission, Joint Research Centre, Institute of Reference Materials and Measurements to ...
Cooper, S., Corbisier, Philippe, Gancberg, David, Gemmati, Donato, Halbmayer, Walter-Michael, Kitchen, Steve, Klein, Christoph L., Mannhalter, Christine, Marki-Zay, János, Melegh, Béla, Neumaier, Michael, Oldenburg, Johannes, Opplinger Leibundgut, Elisabeth, Reitsma, Pieter H., Rieger, Sandra, Schimmel, Heinz G., Spannagl, Michael, Tordai, Attilia, Tosetto, Alberto, Visvikis, Sophie, Zadro, Renata   +20 more
core   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hypoxanthine guanine phosphoribosyl transferase is the most stable reference gene for gene expression analysis by quantitative PCR in peripheral blood mononuclear cells from women with the polycystic ovary syndrome [PDF]

Journal of Medical Biochemistry, 2014
Background: The polycystic ovary syndrome (PCOS) is a frequent endocrine disorder that affects women of reproductive age. As the syndrome is strongly associated with obesity, it is of interest to examine the gene expression differences that accompany its
Vojnović-Milutinović Danijela, Macut Đuro, Božić-Antić Ivana, Bjekić-Macut Jelica, Nikolić Marina, Matić Gordana, Nestorov Jelena   +6 more
doaj  

The Selection of Reference Genes for Quantitative Real-Time PCR in the Ashidan Yak Mammary Gland During Lactation and Dry Period

Animals, 2019
Investigating the critical genes related to milk synthesis is essential for the improvement of the milk yield of the yak. Real-time quantitative polymerase chain reaction (RT-qPCR) is a reliable and widely used method to measure and evaluate gene ...
Xiaoyun Wu, Xuelan Zhou, Xuezhi Ding, Min Chu, Chunnian Liang, Jie Pei, Lin Xiong, Pengjia Bao, Xian Guo, Ping Yan   +9 more
doaj   +1 more source

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes [PDF]

, 2013
BACKGROUND: Retroposed processed gene transcripts are an important source of material for new gene formation on evolutionary timescales. Most prior work on gene retrocopy discovery compared copies in reference genome assemblies to their source genes ...
Ballinger, Tracy J, Broad Institute Genome Sequencing and Analysis Program and Platform,, Ding, Li, Earl, Dent, Ewing, Adam D, Harris, Christopher C, Haussler, David, Wilson, Richard K   +7 more
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Influence of reference genes on expression of TYR, MITF and ASIP genes in tissues of Silky Fowl

浙江大学学报. 农业与生命科学版, 2015
Silky Fowl is a precious local breed containing a large amount of melanin. Therefore, it is considered to have high edible and medicinal value. Study on the related gene expression is helpful to reveal the internal regulation mechanism of melanin ...
Zheng Nenzhu, Li Li, Xin Qingwu, Miao Zhongwei, Zhu Zhiming, Liu Fenghui, Wu Jianfei, Lu Lizhi   +7 more
doaj   +1 more source

A simple and robust method for connecting small-molecule drugs using gene-expression signatures [PDF]

, 2008
Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar ...
B Efron, CC Ting, J Frasor, J Lamb, JD Storey, JJ Chen, JS Warrington, KB Glaser, L Tian, M Lee, N Fujimoto, N Sathyamoorthy, PA Horwitz, R Januchowski, S McHugh, SD Zhang, Shu-Dong Zhang, ST Matalon, Timothy W Gant, VW Armstrong, Y Chen   +20 more
core   +5 more sources

Selection of reference genes in canine uterine tissues

Genetics and Molecular Research, 2016
Real-time quantitative polymerase chain reaction (RT-qPCR) is usually employed in gene expression studies in veterinary research, including in studies on canine pyometra. Canine pyometra is a common clinical disease in bitches. When using RT-qPCR, internal standards, such as reference genes, are necessary to investigate relative gene expression by ...
M, Du, X, Wang, Y W, Yue, P Y, Zhou, W, Yao, X, Li, X B, Ding, X F, Liu, H, Guo, W Z, Ma   +9 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source