Results 81 to 90 of about 2,311,393 (299)

Cross-Product Extensions of the Gene Ontology [PDF]

, 2009
The Gene Ontology is being normalized and extended to include computable logical definitions. These definitions are partitioned into mutually exclusive cross-product sets, many of which reference other OBO Foundry ontologies.
Amelia Ireland, Christopher J. Mungall, David P. Hill, Jane Lomax, Jennifer Deegan, Michael Bada, Midori A. Harris, Tanya Z. Berardini   +7 more
core   +1 more source

Gene duplication in an African cichlid adaptive radiation [PDF]

, 2014
Background Gene duplication is a source of evolutionary innovation and can contribute to the divergence of lineages; however, the relative importance of this process remains to be determined.
Joyce, Domino A, Joyce, Domino A., Jui, Ginger, Lunt, David H., Machado, Heather E, Machado, Heather E., Reilly, Christian R. L., Reilly, Christian R.L., Reilly, Christian RL, Renn, Suzy C. P., Renn, Suzy C.P., Renn, Suzy Cp, Renn, Suzy CP   +12 more
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Housekeeping Genes for Parkinson’s Disease in Humans and Mice

Cells, 2021
A critical aspect of real-time PCR is the presence of housekeeping genes (HKGs) as an internal control for the normalization of expression data for genes of interest.
Anelya Kh. Alieva, Elena V. Filatova, Margarita M. Rudenok, Petr A. Slominsky, Maria I. Shadrina   +4 more
doaj   +1 more source

GeneRank: Using search engine technology for the analysis of microarray experiments [PDF]

, 2005
Copyright @ 2005 Morrison et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Breitling, R, Gilbert, D, Higham, D, Morrison, JL   +3 more
core   +5 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Prevalence of methicillin-resistant Staphylococcus aureus isolated from Moheb Hospital and Miladphenotypic and molecular methods

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2015
Introduction: S. aureus, the second most common cause of nosocomial infections, is regarded as an important factor in the severe infections of the community. Methicillin-resistant strains of this bacterium involve a major pathogen which can cause disease
Z Gomarian, MH Shahhosseiny, M Bayat, MA Mahmoudi, T Nafarieh, M Rahbar   +5 more
doaj  

Identification and Evaluation of qRT-PCR Reference Genes in Melanaphis sacchari

Insects
Appropriate reference genes must be selected for accurate qRT-PCR data to conduct a thorough gene expression analysis in the sorghum aphid (Melanaphis sacchari, Hemiptera, Aphididae). This approach will establish a foundation for gene expression analysis
Kunliang Zou, Tonghan Wang, Minghui Guan, Yang Liu, Jieqin Li, Yanlong Liu, Junli Du, Degong Wu   +7 more
doaj   +1 more source

TRAPID : an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes [PDF]

, 2013
Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise.
Deforce, Dieter, Proost, Sebastian, Van Bel, Michiel, Van de Peer, Yves, Van Neste, Christophe, Vandepoele, Klaas   +5 more
core   +2 more sources