Results 101 to 110 of about 2,311,393 (299)

EPSILON: an eQTL prioritization framework using similarity measures derived from local networks [PDF]

, 2013
Motivation: When genomic data are associated with gene expression data, the resulting expression quantitative trait loci (eQTL) will likely span multiple genes.
Cloots, Lore, Demeester, Piet, Fostier, Jan, Marchal, Kathleen, Verbeke, Lieven   +4 more
core   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Validation of suitable internal control genes for expression studies in aging. [PDF]

, 2009
Quantitative data from experiments of gene expression are often normalized through levels of housekeeping genes transcription by assuming that expression of these genes is highly uniform. This practice is being questioned as it becomes increasingly clear
Bacalini, MARIA GIULIA, Burkle, A, Caiafa, Paola, Calabrese, Roberta, Chevanne, M, Ciccarone, Fabio, Guastafierro, Tiziana, MORENO VILLANUEVA, M, Reale, Anna, Zampieri, Michele   +9 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Hypoxanthine guanine phosphoribosyl transferase is the most stable reference gene for gene expression analysis by quantitative PCR in peripheral blood mononuclear cells from women with the polycystic ovary syndrome [PDF]

Journal of Medical Biochemistry, 2014
Background: The polycystic ovary syndrome (PCOS) is a frequent endocrine disorder that affects women of reproductive age. As the syndrome is strongly associated with obesity, it is of interest to examine the gene expression differences that accompany its
Vojnović-Milutinović Danijela, Macut Đuro, Božić-Antić Ivana, Bjekić-Macut Jelica, Nikolić Marina, Matić Gordana, Nestorov Jelena   +6 more
doaj  

The Selection of Reference Genes for Quantitative Real-Time PCR in the Ashidan Yak Mammary Gland During Lactation and Dry Period

Animals, 2019
Investigating the critical genes related to milk synthesis is essential for the improvement of the milk yield of the yak. Real-time quantitative polymerase chain reaction (RT-qPCR) is a reliable and widely used method to measure and evaluate gene ...
Xiaoyun Wu, Xuelan Zhou, Xuezhi Ding, Min Chu, Chunnian Liang, Jie Pei, Lin Xiong, Pengjia Bao, Xian Guo, Ping Yan   +9 more
doaj   +1 more source

Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers [PDF]

, 2011
Background: Gene regulation through cis-regulatory elements plays a crucial role in development and disease. A major aim of the post-genomic era is to be able to read the function of cis-regulatory elements through scrutiny of their DNA sequence ...
Bronner, Marianne E., Elgar, Greg, Parker, Hugo J., Piccinelli, Paul, Sauka-Spengler, Tatjana   +4 more
core   +5 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Influence of reference genes on expression of TYR, MITF and ASIP genes in tissues of Silky Fowl

浙江大学学报. 农业与生命科学版, 2015
Silky Fowl is a precious local breed containing a large amount of melanin. Therefore, it is considered to have high edible and medicinal value. Study on the related gene expression is helpful to reveal the internal regulation mechanism of melanin ...
Zheng Nenzhu, Li Li, Xin Qingwu, Miao Zhongwei, Zhu Zhiming, Liu Fenghui, Wu Jianfei, Lu Lizhi   +7 more
doaj   +1 more source

Selection of reference genes in canine uterine tissues

Genetics and Molecular Research, 2016
Real-time quantitative polymerase chain reaction (RT-qPCR) is usually employed in gene expression studies in veterinary research, including in studies on canine pyometra. Canine pyometra is a common clinical disease in bitches. When using RT-qPCR, internal standards, such as reference genes, are necessary to investigate relative gene expression by ...
M, Du, X, Wang, Y W, Yue, P Y, Zhou, W, Yao, X, Li, X B, Ding, X F, Liu, H, Guo, W Z, Ma   +9 more
openaire   +2 more sources