Results 31 to 40 of about 1,279,789 (265)
Current Opinion in Pharmacology, 2004 Regulatory T (TR) cells are a subset of T cells that function to control immune responses. Different populations of TR cells have been described, including thymically derived CD4(+)CD25+ TR cells and Tr1 cells induced in the periphery through exposure to antigen.
Thompson, C, Powrie, F
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T cell-intrinsic role of IL-6 signaling in primary and memory responses
eLife, 2014 Innate immune recognition is critical for the induction of adaptive immune responses; however the underlying mechanisms remain incompletely understood.
Simone A Nish +14 more
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T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity. [PDF]
PLoS Medicine, 2005 BACKGROUND: Synthetic peptides, representing CD4(+) T cell epitopes, derived from the primary sequence of allergen molecules have been used to down-regulate allergic inflammation in sensitised individuals. Treatment of allergic diseases with peptides may
Adrienne Verhoef +3 more
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Regulatory T Cells in AKI [PDF]
Journal of the American Society of Nephrology, 2013 Human AKI is manifested by inflammation, and an early feature in the pathogenesis is the accumulation of immune cells in the kidney. To understand the pathophysiology of AKI, results from animal models have shown a causal relation between the leukocyte activation and infiltration to the kidney after kidney ischemia-reperfusion.
Gilbert R, Kinsey +2 more
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Regulatory T Cells in Autoimmmunity [PDF]
Annual Review of Immunology, 2000 Clonal deletion of autoreactive T cells in the thymus is not the sole mechanism for the induction of tolerance to self-antigens since partial depletion of peripheral CD4+T cells from neonatal and adult animals results in the development of organ-specific autoimmunity.
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Tr1-like T cells- an enigmatic regulatory T cell lineage
Frontiers in Immunology, 2016 The immune system evolved to respond to foreign invaders and prevent autoimmunity to self-antigens. Several types of regulatory T cells facilitate the latter process.
Anna Malgorzata White +2 more
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Regulatory T cells in paracoccidioidomycosis [PDF]
Virulence, 2018 This review addresses the role of regulatory T cells (Tregs), which are essential for maintaining peripheral tolerance and controlling pathogen immunity, in the host response against Paracoccidioides brasiliensis, a primary fungal pathogen. A brief introduction on the general features of Treg cells summarizes their main functions, subpopulations ...
Vera L. G. Calich +2 more
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Current Opinion in Immunology, 2001 There is now compelling evidence that CD4(+) T cells that specialize in the suppression of immune responses play a key role in the control of immune pathology. Recently, there have been a number of reports that have provided information on the generation of CD4(+) regulatory T cells in the thymus and in the periphery.
Read, S, Powrie, F
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Frontiers in Immunology, 2023 The regulatory T (Treg) cells constitute a functionally defined subpopulation of T cells that modulate the immune system and maintain immune tolerance through suppression of the development of autoimmune responses to self-antigens and allergic reactions ...
Jefferson Russo Victor +2 more
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Regulatory T Cells in Atherogenesis
Journal of Atherosclerosis and Thrombosis, 2012 Atherosclerosis is believed to be an inflammatory condition of the arterial wall. It has become apparent that various types of cells of innate and adaptive immunity participate in atherogenesis. T cells are of particular interest because they mediate pathogenic immune responses involved in the acceleration of atherosclerosis.
Sasaki, Naoto +3 more
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