Results 71 to 80 of about 153,606 (275)
RelA Inhibits Bacillus subtilis Motility and Chaining [PDF]
ABSTRACT The nucleotide second messengers pppGpp and ppGpp [(p)ppGpp] are responsible for the global downregulation of transcription, translation, DNA replication, and growth rate that occurs during the stringent response. More recent studies suggest that (p)ppGpp is also an important effector in many nonstringent processes ...
Qutaiba O, Ababneh, Jennifer K, Herman
openaire +2 more sources
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang +5 more
wiley +1 more source
PIAS3-mediated RelA SUMOylation is dependent on RelA DNA binding.
A) HEK 293T cells were transfected with Flag-tagged PIAS3, V5-tagged RelA and RelA mutants defective in DNA binding (39I and 36A) as indicated. The transactivation activity was measured by NF-κB luciferase activity.
Molly Kulesz-Martin (162511) +3 more
core +1 more source
FORTRESS EUROPE BREACHED: POLITICAL AND ECONOMIC IMPACT OF THE RECENT REFUGEE CRISIS ON EUROPEAN STATES [PDF]
The onset of the Syrian civil war, the expansion of the military influence of the Islamic State in the Middle and Near East and the ongoing conflicts in Africa has caused a significant number of refugees from the affected areas to flee towards Europe ...
Adrian-Ioan Damoc
doaj
Escherichia coli RelA Regulation via Its C-Terminal Domain
One of the most important stress responses in bacteria is the stringent response. The main player in this response is the signal molecule (p)ppGpp, which is synthesized by a Rel family protein. In Escherichia coli, RelA is the main synthetase of (p)ppGpp
Ilana Kaspy, Gad Glaser
doaj +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
(A) Endogenous RelA was immunoprecipitated from KMM1 whole cell lysates and its interaction with endogenous YY1 was analyzed by immunoblotting as indicated.
Sunil K. Noothi (432654) +6 more
core +1 more source
Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
Identification of preferred RelA SUMOylation site.
A) Mouse 3T3 cells were transfected with His-tagged SUMO3, v5-tagged RelA mutants 37R, 122R (121K>R/122K>R), and 222R as indicated, and Flag-tagged PIAS3 plasmids.
Molly Kulesz-Martin (162511) +3 more
core +1 more source

