Results 31 to 40 of about 9,817 (201)

Phenomenon-based evaluation of relative biological effectiveness of ion beams by means of the multiscale approach

Cancer Nanotechnology, 2019
Background Relative biological effectiveness (RBE) is a key quantity for the description of radiobiological effects induced by charged-particle irradiation in the context of ion-beam cancer therapy.
Alexey Verkhovtsev, Eugene Surdutovich, Andrey V. Solov’yov   +2 more
doaj   +1 more source

Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC

Frontiers in Physics, 2021
Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume (SV) by single ionizing particles traversing the SV or passing by.
A. Bianchi, A. Bianchi, A. Bianchi, A. Selva, P. Colautti, G. Petringa, P. Cirrone, B. Reniers, A. Parisi, F. Vanhavere, V. Conte   +10 more
doaj   +1 more source

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R., Ledingham, K. W. D., Ma, C-M., Shikazono, N.   +3 more
core   +3 more sources

Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model

Clinical and Translational Radiation Oncology, 2019
Background and purposes: Carbon ion radiotherapy (CIRT) with raster scanning technology is a promising treatment for lung cancer and thoracic malignancies.
Cheng Zhou, Bleddyn Jones, Mahmoud Moustafa, Bing Yang, Stephan Brons, Liji Cao, Ying Dai, Christian Schwager, Ming Chen, Oliver Jaekel, Longhua Chen, Juergen Debus, Amir Abdollahi   +12 more
doaj   +1 more source

Commissioning a newly developed treatment planning system, VQA Plan, for fast-raster scanning of carbon-ion beams

PLoS ONE, 2022
In this study, we report our experience in commissioning a commercial treatment planning system (TPS) for fast-raster scanning of carbon-ion beams. This TPS uses an analytical dose calculation algorithm, a pencil-beam model with a triple Gaussian form ...
Masashi Yagi, Toshiro Tsubouchi, Noriaki Hamatani, Masaaki Takashina, Hiroyasu Maruo, Shinichiro Fujitaka, Hideaki Nihongi, Kazuhiko Ogawa, Tatsuaki Kanai   +8 more
doaj   +2 more sources

Characterizing Radiation Effectiveness in Ion-Beam Therapy Part II: Microdosimetric Detectors

Frontiers in Physics, 2020
The specific advantages of ion beams for application in tumor therapy are attributed to their different macroscopic and microscopic energy deposition pattern as compared to conventional photon radiation.
Paolo Colautti, Giulio Magrin, Hugo Palmans, Hugo Palmans, Miguel A. Cortés-Giraldo, Valeria Conte   +5 more
doaj   +1 more source

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos. [PDF]

PLoS ONE, 2018
The increasing use of proton radiotherapy during the last decade and the rising number of long-term survivors has given rise to a vital discussion on potential effects on normal tissue.
Emília Rita Szabó, Michael Brand, Stefan Hans, Katalin Hideghéty, Leonhard Karsch, Elisabeth Lessmann, Jörg Pawelke, Michael Schürer, Elke Beyreuther   +8 more
doaj   +1 more source

Clonogenic Survival RBE Calculations in Carbon Ion Therapy: The Importance of the Absolute Values of α and β in the Photon Dose-Response Curve and a Strategy to Mitigate Their Anticorrelation

Quantum Beam Science, 2023
The computation of the relative biological effectiveness (RBE) is a fundamental step in the planning of cancer radiotherapy treatments with accelerated ions.
Alessio Parisi, Chris J. Beltran, Keith M. Furutani   +2 more
doaj   +1 more source

Dose–volume constraints for head‐and‐neck cancer in carbon ion radiotherapy: A literature review

Cancer Medicine, 2023
Background Carbon ion radiotherapy (CIRT) has been applied in cancer treatment for over 25 years. However, guidelines for dose–volume constraints have not been established yet.
Maria Varnava, Atsushi Musha, Mutsumi Tashiro, Nobuteru Kubo, Naoko Okano, Hidemasa Kawamura, Tatsuya Ohno   +6 more
doaj   +1 more source

Comparison of X-ray and gamma-ray dose-response curves for pink somatic mutations in Tradescantia clone 02 [PDF]

, 1976
Microdosimetric data indicate that the mean specific energy,zeta, produced by individual charged particles from X rays and gamma rays is different for the two radiation qualities by nearly a factor of two.
A. G. Underbrink, A. G. Underbrink, A. G. Underbrink, A. G. Underbrink, A. G. Underbrink, A. H. Sparrow, A. H. Sparrow, A. M. Kellerer, A. M. Kellerer, A. M. Kellerer, C. H. Nauman, D. E. Lea, E. Schmid, J. F. Malone, O. Hug, R. E. Mills, W. H. Ellett, W. K. Sinclair   +17 more
core   +1 more source