Impact of anatomical changes on simulated proton arc therapy and intensity-modulated proton therapy for lung cancer. [PDF]
J Appl Clin Med PhysAbstract Purpose : During lung cancer radiotherapy, inter‐fractional anatomical changes may cause the delivered dose to deviate from the primary plan, affecting tumor control and increasing the risk of normal tissue damage. This study aims to evaluate the impact of anatomical changes on the dosimetric and radiobiological performance of simulated proton
Chen W +10 more
europepmc +2 more sources
The relative biological effectiveness for carbon and oxygen ion beams using the raster-scanning technique in hepatocellular carcinoma cell lines. [PDF]
PLoS ONE, 2014 BACKGROUND: Aim of this study was to evaluate the relative biological effectiveness (RBE) of carbon (12C) and oxygen ion (16O)-irradiation applied in the raster-scanning technique at the Heidelberg Ion beam Therapy center (HIT) based on clonogenic ...
Daniel Habermehl +9 more
doaj +1 more source
Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement
Geophysical Monograph Series, Page 27-82., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm +2 more
wiley +1 more source
Radiation Oncology, 2022 Background Variable relative biological effectiveness (vRBE) in proton therapy might significantly modify the prediction of RBE-weighted dose delivered to a patient during proton therapy.
Magdalena Garbacz +15 more
doaj +1 more source
Assessing the influence of microdosimetric formalism on calculations of relative biological effectiveness in carbon ion radiotherapy [PDF]
Precis Radiat OncolPrecision Radiation Oncology, EarlyView.
Hartzell S +4 more
europepmc +2 more sources
Journal of Medical Physics, 2019 Purpose: The purpose of this study is to evaluate the influence of variable relative biological effectiveness (RBE) of proton beam and dose fractionation has on dose distribution and to establish a new three-dimensional dose evaluation method for proton ...
Daisuke Kobayashi +10 more
doaj +1 more source
Frontiers in Oncology, 2016 Radiotherapy of solid tumors with charged particles holds several advantages in comparison to photon therapy; among them conformal dose distribution in the tumor, improved sparing of tumor-surrounding healthy tissue, and an increased relative biological ...
Nicole Bernadette Averbeck +8 more
doaj +1 more source
Advances in Radiation Oncology, 2021 Purpose: During radiation therapy for pediatric brain tumors, the brainstem is a critical organ at risk, possibly with different radio-sensitivity across its substructures.
Lars Fredrik Fjæra, MSc +7 more
doaj +1 more source
Relative biological effectiveness (RBE) and distal edge effects of proton radiation on early damage in vivo [PDF]
Acta Oncologica, 2017 The aim of the present study was to examine the RBE for early damage in an in vivo mouse model, and the effect of the increased linear energy transfer (LET) towards the distal edge of the spread-out Bragg peak (SOBP).The lower part of the right hind limb of CDF1 mice was irradiated with single fractions of either 6 MV photons, 240 kV photons or ...
Sørensen, Brita Singers; id_orcid 0000-0002-3955-4735 +8 more
openaire +2 more sources
Cancer Nanotechnology, 2019 Background Relative biological effectiveness (RBE) is a key quantity for the description of radiobiological effects induced by charged-particle irradiation in the context of ion-beam cancer therapy.
Alexey Verkhovtsev +2 more
doaj +1 more source