Results 21 to 30 of about 9,939 (212)

Relative biological effectiveness (RBE) and distal edge effects of proton radiation on early damage in vivo [PDF]

Acta Oncologica, 2017
The aim of the present study was to examine the RBE for early damage in an in vivo mouse model, and the effect of the increased linear energy transfer (LET) towards the distal edge of the spread-out Bragg peak (SOBP).The lower part of the right hind limb of CDF1 mice was irradiated with single fractions of either 6 MV photons, 240 kV photons or ...
Sørensen, Brita Singers, Bassler, Niels, Nielsen, Steffen, Horsman, Michael R, Grzanka, Leszek, Spejlborg, Harald, Swakoń, Jan, Olko, Paweł, Overgaard, Jens   +8 more
openaire   +2 more sources

Efficient rejoining of DNA double-strand breaks despite increased cell-killing effectiveness following spread-out Bragg peak carbon-ion irradiation

Frontiers in Oncology, 2016
Radiotherapy of solid tumors with charged particles holds several advantages in comparison to photon therapy; among them conformal dose distribution in the tumor, improved sparing of tumor-surrounding healthy tissue, and an increased relative biological ...
Nicole Bernadette Averbeck, Jana eTopsch, Jana eTopsch, Michael eScholz, Wilma eKraft-Weyrather, Marco eDurante, Marco eDurante, Gisela eTaucher-Scholz, Gisela eTaucher-Scholz   +8 more
doaj   +1 more source

Biological Dose Estimation Model for Proton Beam Therapy [PDF]

, 2015
Purpose: The recommended value for the relative biological effectiveness (RBE) of proton beams is currently assumed to be 1.1. However, there is increasing evidence that RBE increases towards the end of proton beam range that may increase the biological ...
Anferov, Vladimir, Das, Indra J.
core   +1 more source

Proton and helium ion radiotherapy for meningioma tumors: a Monte Carlo-based treatment planning comparison [PDF]

, 2018
Background: Due to their favorable physical and biological properties, helium ion beams are increasingly considered a promising alternative to proton beams for radiation therapy.
Cerutti, Francesco, Chen, Wenjing, Debus, Jürgen, Ferrari, Alfredo, Haberer, Thomas, Mairani, Andrea, Parodi, Katia, Sala, Paola, Tessonnier, Thomas   +8 more
core   +3 more sources

Phenomenon-based evaluation of relative biological effectiveness of ion beams by means of the multiscale approach

Cancer Nanotechnology, 2019
Background Relative biological effectiveness (RBE) is a key quantity for the description of radiobiological effects induced by charged-particle irradiation in the context of ion-beam cancer therapy.
Alexey Verkhovtsev, Eugene Surdutovich, Andrey V. Solov’yov   +2 more
doaj   +1 more source

Microdosimetric analysis confirms similar biological effectiveness of external exposure to gamma-rays and internal exposure to 137Cs, 134Cs, and 131I. [PDF]

PLoS ONE, 2014
The risk of internal exposure to 137Cs, 134Cs, and 131I is of great public concern after the accident at the Fukushima-Daiichi nuclear power plant. The relative biological effectiveness (RBE, defined herein as effectiveness of internal exposure relative ...
Tatsuhiko Sato, Kentaro Manabe, Nobuyuki Hamada   +2 more
doaj   +1 more source

Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC

Frontiers in Physics, 2021
Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume (SV) by single ionizing particles traversing the SV or passing by.
A. Bianchi, A. Bianchi, A. Bianchi, A. Selva, P. Colautti, G. Petringa, P. Cirrone, B. Reniers, A. Parisi, F. Vanhavere, V. Conte   +10 more
doaj   +1 more source

Biological Effects of Stellar Collapse Neutrinos [PDF]

, 1995
Massive stars in their final stages of collapse radiate most of their binding energy in the form of MeV neutrinos. The recoil atoms that they produce in elastic scattering off nuclei in organic tissue create radiation damage which is highly effective in ...
A. Drukier, D. M. Raup, D. Raup, D. T. Goodhead, D. T. Goodhead, J. Ellis, J. F. Ziegler, J. I. Collar, J. Kiefer, J. N. Bahcall, J. N. Bahcall, L. Sabatier, L. W. Brackenbusk, M. A. Kadhim, M. A. Ruderman, S. H. Jiang, S. M. Stanley, S. Z. Aghamohammadi, T. C. Yang, V. Michalik   +19 more
core   +2 more sources

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R., Ledingham, K. W. D., Ma, C-M., Shikazono, N.   +3 more
core   +3 more sources

Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model

Clinical and Translational Radiation Oncology, 2019
Background and purposes: Carbon ion radiotherapy (CIRT) with raster scanning technology is a promising treatment for lung cancer and thoracic malignancies.
Cheng Zhou, Bleddyn Jones, Mahmoud Moustafa, Bing Yang, Stephan Brons, Liji Cao, Ying Dai, Christian Schwager, Ming Chen, Oliver Jaekel, Longhua Chen, Juergen Debus, Amir Abdollahi   +12 more
doaj   +1 more source