Results 201 to 210 of about 22,102,937 (361)

Improvements in medical therapy and prognosis for patients with HFrEF following the 2021 ESC HF guidelines

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The guideline‐directed medical therapy (GDMT) sequencing strategy for patients with heart failure (HF) and reduced ejection fraction (HFrEF) underwent a paradigm shift with the 2021 ESC HF guidelines, from stepwise escalation to rapid simultaneous initiation of quadruple therapy.
Kristian Berge   +12 more
wiley   +1 more source

Proteins associated with rehospitalization, mortality and diuretic resistance in acutely decompensated heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Most proteomic analyses in patients with heart failure (HF) focus on the stable ambulatory setting; pathways that drive acute decompensated heart failure (ADHF) are largely uncharacterized. We aimed to examine the associations of cardiometabolic proteins with HF rehospitalization, mortality and diuretic response in patients with ADHF ...
Kenneth T. Hubbell   +8 more
wiley   +1 more source

Sympathoadrenal and renin-angiotensin systems in the development of two-kidney, one clip renal hypertension in rats. [PDF]

open access: bronze, 1980
Michael J. Antonaccio   +4 more
openalex   +1 more source

Interconnected pathways and emerging therapies in chronic kidney disease and heart failure: A comprehensive review

open access: yesESC Heart Failure, EarlyView.
Abstract Chronic kidney disease (CKD) and chronic heart failure (HF) frequently coexist and, when comorbid, are associated with poorer outcomes. These two diseases have common risk factors, such as diabetes, obesity and hypertension, and common pathophysiological connected mechanisms, including inflammation, endothelial dysfunction, neurohormonal ...
Johann Bauersachs   +2 more
wiley   +1 more source

Angiotensin receptor‐neprilysin inhibitors in concurrent heart failure with reduced ejection fraction and kidney failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Angiotensin receptor‐neprilysin inhibitor (ARNI) therapy has demonstrated improved outcomes in heart failure with reduced ejection fraction (HFrEF). However, its benefits in patients with concomitant kidney failure undergoing replacement therapy remain uncertain. Methods and results Using the National Health Insurance Service database, we
Mi‐Hyang Jung   +8 more
wiley   +1 more source

The pulmonary artery pulsatility index in patients with severe aortic stenosis undergoing valve replacement

open access: yesESC Heart Failure, EarlyView.
Abstract Background and aims The pulmonary artery pulsatility index (PAPi), that is, the pulmonary artery pulse pressure (PAPP) divided by the mean right atrial pressure (mRAP), is an increasingly used invasive index of right ventricular function. We sought to assess the prognostic impact of the PAPi in unselected patients with aortic stenosis (AS ...
Laura A. Rechsteiner   +9 more
wiley   +1 more source

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