Results 221 to 230 of about 22,692,331 (249)

Effects of Hormone Replacement Treatment with Estrogen and Progestins on the Vascular Renin-Angiotensin System of Ovariectomized Rats. [PDF]

Int J Mol Sci
Menezes LA, Endlich PW, Lima DSS, Peluso AA, de Almeida SA, Borgo MV, Santos RAS, de Abreu GR.   +7 more
europepmc   +1 more source

Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Mian Muhammad Hassan Ahmed, Rehmana Waris, Samra Batool, Rahmat Gul Omarzai, Abdur Rehman   +4 more
wiley   +1 more source

Discontinuation versus continuation of renin-angiotensin system inhibitors in chronic kidney disease stage 3-5 patients: a systematic review and meta-analysis. [PDF]

Front Pharmacol
Chen IW, Lin YH, Wu VC, Chen JY, Wu MH.
europepmc   +1 more source

A Novel SCNN1B Mutation in a Neonate With Systemic Pseudohypoaldosteronism Type 1: Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Early recognition of PHA1B in neonates with persistent hyperkalemia and hyponatremia is important for timely intervention. Genetic testing confirms the diagnosis, guiding long‐term management. This case highlights a novel SCNN1B mutation, expanding the genetic spectrum and emphasizing the need for lifelong monitoring to prevent life ...
Ensiyeh Bahadoran, Fatemeh Saffari, Sahar Moghbelinejad   +2 more
wiley   +1 more source

Chronic Copper Overload Triggers Inflammation in Mesenteric PVAT Alongside Changes in Renin-Angiotensin System-Related Pathways. [PDF]

Nutrients
Mawandji NBS, Lisboa NADS, Gomes KN, Vieira JM, Simão JJ, Alonso-Vale MI, Nunes KZ, Vassallo DV, Bolsoni-Lopes A.   +8 more
europepmc   +1 more source

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 198-207, January 2026.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Maintenance of blood pressure by reactive increases in plasma renin activity during salt depletion and renin-angiotensin system inhibition. [PDF]

J Hypertens
Sealey JE, Blumenfeld JD.
europepmc   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Efficacy of Esaxerenone Plus a Renin-Angiotensin System Inhibitor or Calcium Channel Blocker for Nocturnal Hypertension: A Post Hoc Analysis. [PDF]

Am J Hypertens
Kario K, Ito S, Itoh H, Rakugi H, Okuda Y, Yamakawa S.   +5 more
europepmc   +1 more source

Antihypertensive Effects of Curcumin/Turmeric Supplementation in Prediabetes and Diabetes: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Pooled data from randomised controlled trials demonstrate that supplementation with curcumin or turmeric leads to a significant reduction in systolic blood pressure (SBP) in individuals with prediabetes and type 2 diabetes. While the overall effect on diastolic blood pressure (DBP) was not significant, a pre‐specified subgroup analysis showed a ...
Hossein Bahari, Maryam Sharifi, Zahra Nejad Shahrokh Abadi, Mostafa Shahraki Jazinaki, Haniyeh Golafrouz, Zahra Asadi   +5 more
wiley   +1 more source