Alterations in the renin-angiotensin system during septic shock. [PDF]
Benaroua C +10 more
europepmc +1 more source
Cancer Comorbidities: Clinical Impacts, Mechanistic Insights, and Management Strategies
This review focuses on cancer comorbidities, examining their clinical impacts and mechanistic insights. It further examines key management challenges, including evidence gaps, the lack of precise assessment tools, limited management frameworks, and underdeveloped multidisciplinary collaborations.
Taoxing Peng +15 more
wiley +1 more source
Propofol exerted the neuroprotective effects by regulating renin-angiotensin system and mitochondria-associated endoplasmic reticulum membrane in the postoperative cognitive dysfunction. [PDF]
Ding W +5 more
europepmc +1 more source
ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert +3 more
wiley +1 more source
Correction to "Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension Through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress". [PDF]
europepmc +1 more source
Renin-angiotensin system as an emerging target to modulate adult neurogenesis in health and disease. [PDF]
Rodríguez-Pallares J +3 more
europepmc +1 more source
Abstract Introduction The pathophysiology of chronic kidney disease (CKD) and type 2 diabetes (T2D) is multifactorial and associated with a plethora of underlying conditions and complications. Their link is reciprocal and understanding its nature, particularly over time, could improve the health of many.
Andreas Matheou +13 more
wiley +1 more source
Renin-Angiotensin System Inhibitors in Patients With Nonproteinuric Chronic Kidney Disease and Kidney Outcomes: Findings From the CRIC Study. [PDF]
Shulman R +5 more
europepmc +1 more source
Abstract Introduction Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction tools that include social determinants and demographic complexity. We developed and validated an ensemble machine learning model for three‐year DKD/DN risk prediction with deployment readiness ...
Ayla M. Tourkmani +5 more
wiley +1 more source
Expression of the Renin-Angiotensin System in the Heart, Aorta, and Perivascular Adipose Tissue in an Animal Model of Type 1 Diabetes. [PDF]
Martín-Carro B +12 more
europepmc +1 more source

