Results 221 to 230 of about 172,199 (241)

Alterations in the renin-angiotensin system during septic shock. [PDF]

open access: yesAnn Intensive Care
Benaroua C   +10 more
europepmc   +1 more source

Cancer Comorbidities: Clinical Impacts, Mechanistic Insights, and Management Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
This review focuses on cancer comorbidities, examining their clinical impacts and mechanistic insights. It further examines key management challenges, including evidence gaps, the lack of precise assessment tools, limited management frameworks, and underdeveloped multidisciplinary collaborations.
Taoxing Peng   +15 more
wiley   +1 more source

ClC‐2 Contributes to Hypotonicity‐Induced Adrenal Aldosterone Secretion

open access: yesActa Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The zona glomerulosa (ZG) of the adrenal cortex regulates blood pressure and electrolyte homeostasis through aldosterone production. In ZG cells, potassium and angiotensin II (Ang II) trigger calcium oscillations that drive aldosterone synthesis.
Marina Volkert   +3 more
wiley   +1 more source

Renin-angiotensin system as an emerging target to modulate adult neurogenesis in health and disease. [PDF]

open access: yesStem Cell Res Ther
Rodríguez-Pallares J   +3 more
europepmc   +1 more source

Progression of albumin/creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) over 24 years in people with type 2 diabetes. Drivers, potential protectors and associated mortality

open access: yesDiabetic Medicine, Volume 43, Issue 3, March 2026.
Abstract Introduction The pathophysiology of chronic kidney disease (CKD) and type 2 diabetes (T2D) is multifactorial and associated with a plethora of underlying conditions and complications. Their link is reciprocal and understanding its nature, particularly over time, could improve the health of many.
Andreas Matheou   +13 more
wiley   +1 more source

Literature‐informed ensemble machine learning for three‐year diabetic kidney disease risk prediction in type 2 diabetes: Development, validation, and deployment of the PSMMC NephraRisk model

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1997-2026, March 2026.
Abstract Introduction Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction tools that include social determinants and demographic complexity. We developed and validated an ensemble machine learning model for three‐year DKD/DN risk prediction with deployment readiness ...
Ayla M. Tourkmani   +5 more
wiley   +1 more source

Expression of the Renin-Angiotensin System in the Heart, Aorta, and Perivascular Adipose Tissue in an Animal Model of Type 1 Diabetes. [PDF]

open access: yesInt J Mol Sci
Martín-Carro B   +12 more
europepmc   +1 more source

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