Global heart failure epidemiology versus enrolment in pivotal trials: A formidable mismatch
Abstract Aims Randomized clinical trials (RCTs) that inform international clinical practice guidelines should adequately represent regions burdened with disease. We aimed to assess the geographic representativeness of pivotal heart failure (HF) RCTs using two methodological approaches.
Guillaume Baudry+8 more
wiley +1 more source
Evidence for a role for a uterine renin-angiotensin system in decidualization in rats [PDF]
P. M. Squires, T. G. Kennedy
openalex +1 more source
Inhibition of the Renin-Angiotensin System Improves Hemodynamic Function of the Diabetic Rat Heart by Restoring Intracellular Calcium Regulation. [PDF]
Paulik KA+7 more
europepmc +1 more source
The impact of sodium chloride (NaCl) supplementation on proximal and distal tubular reabsorption in acute heart failure (AHF). Abstract Aims We questioned the long‐standing paradigm that sodium/chloride restriction is essential for effective decongestion in acute heart failure (AHF). This study compared the decongestive effects of two isotonic infusion
Jan Biegus+7 more
wiley +1 more source
Secreted Protein Acidic and Rich in Cysteine (SPARC) Induced by the Renin-Angiotensin System Causes Endothelial Inflammation in the Early Stages of Hypertensive Vascular Injury. [PDF]
Toba H+5 more
europepmc +1 more source
Research Progress of Food-Derived Antihypertensive Peptides in Regulating the Key Factors of the Renin-Angiotensin System. [PDF]
Yao X, Cao X, Chen L, Liao W.
europepmc +1 more source
Cardiac resynchronization therapy (CRT) as an enabler for guideline‐directed medical therapy (GDMT) in the Swedish Heart Failure Registry (SwedeHF). The figure summarizes the selection of the study population, changes in GDMTs and loop diuretic use/doses from baseline to 1.5‐year follow‐up in patients receiving versus not receiving CRT, and reports the
Daniela Tomasoni+17 more
wiley +1 more source
The renin—angiotensin system in drinking and cardiovascular responses to isoprenaline in the rat
Mark D. Evered, Marilyn M. Robinson
openalex +2 more sources
Vasoinhibin is Generated by the Renin-angiotensin System.
Núñez FF+9 more
europepmc +1 more source
Phosphoproteomics for studying signaling pathways evoked by hormones of the renin-angiotensin system: A source of untapped potential. [PDF]
Souza-Silva IM+3 more
europepmc +1 more source