Results 11 to 20 of about 254,005 (338)
The renin–angiotensin system: a possible new target for depression
BMC Medicine, 2017 Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in multiple pathways related to neurodevelopment ...
João Vian +9 more
doaj +2 more sources
A New Perspective on the Renin-Angiotensin System
Diagnostics, 2022 Cardiovascular disease (CVD) is the leading cause of death in the world. Hypertension is a serious medical problem not only in adults but also in children and adolescents.
A. Martyniak, P. Tomasik
semanticscholar +1 more source
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
Circulation Research, 2020 ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory ...
Mahmoud Gheblawi +8 more
semanticscholar +1 more source
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
New England Journal of Medicine, 2020 RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain.
M. Vaduganathan +5 more
semanticscholar +1 more source
Emerging Microbes and Infections, 2020 The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor blockers
J. Meng +12 more
semanticscholar +1 more source
Renin-Angiotensin System in Pathogenesis of Atherosclerosis and Treatment of CVD
International Journal of Molecular Sciences, 2021 Atherosclerosis has complex pathogenesis, which involves at least three serious aspects: inflammation, lipid metabolism alterations, and endothelial injury.
A. Poznyak +5 more
semanticscholar +1 more source
Cardiovascular Research, 2020 Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of mortality worldwide, and its importance is further emphasized in the context of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
R. Kreutz +10 more
semanticscholar +1 more source
Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19
New England Journal of Medicine, 2020 Background There is concern about the potential of an increased risk related to medications that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus disease 2019 (Covid-19), because the viral receptor is angiotensin ...
H. Reynolds +15 more
semanticscholar +1 more source
Renin-Angiotensin System Blockers and the COVID-19 Pandemic
HYPERTENSION, 2020 During the spread of the severe acute respiratory syndrome coronavirus-2, some reports of data still emerging and in need of full analysis indicate that certain groups of patients are at risk of COVID-19.
A. Danser, M. Epstein, D. Batlle
semanticscholar +1 more source
Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19
New England Journal of Medicine, 2020 Background A potential association between the use of angiotensin-receptor blockers (ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus disease 2019 (Covid-19) has not been well studied.
G. Mancia +4 more
semanticscholar +1 more source