Results 11 to 20 of about 174,628 (339)
Juxtaglomerular apparatus hyperplasia under dual angiotensin blockade. A footprint of adequate RAS inhibition or a concern for renal fibrosis? [PDF]
BMC Nephrology, 2012 Background Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach.
Fernandez-Fernandez Beatriz +5 more
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Renin-Angiotensin System [PDF]
New England Journal of Medicine, 1975 ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire +5 more sources
Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure [PDF]
, 2020 Aims Activation of the renin-angiotensin-aldosterone system plays an important role in the pathophysiology of heart failure (HF) and has been associated with poor prognosis.
Anker, Stefan D. +17 more
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Hepcidin is potential regulator for renin activity
PLoS ONE, 2022 An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone ...
Jaakko Piesanen +7 more
doaj +2 more sources
Nicotine and the renin-angiotensin system [PDF]
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2018 Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in constant decline since the 1950s, the introduction of e-cigarettes or electronic nicotine delivery systems 10 yr ago has attracted former smokers as well as a new generation of consumers.
Eric Lazartigues +4 more
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Aging and the Renin-Angiotensin System [PDF]
Hypertension, 2012 Angiotensin II (Ang II), the dominant effector molecule of the renin-angiotensin system (RAS), exerts its effects on binding of 2 pharmacologically distinct rhodopsin-like G protein–associated receptors, the type 1 and the type 2 (AT1 and AT2) receptors.1 Human cells express a single AT1 receptor, whereas 2 isoforms, AT1A and AT1B with 95% of amino ...
Conti, Sara +2 more
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The renin–angiotensin system: a possible new target for depression
BMC Medicine, 2017 Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in multiple pathways related to neurodevelopment ...
João Vian +9 more
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Alamandine and Its Receptor MrgD Pair Up to Join the Protective Arm of the Renin-Angiotensin System [PDF]
, 2019 Only a few years ago, alamandine was found to be a member of the protective arm of the renin-angiotensin system. It turned out to be an endogenous ligand of the G protein-coupled receptor MrgD.
Schleifenbaum, Johanna
core +1 more source
Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review [PDF]
BIO Web of ConferencesOne of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation.
Capritasari Rafiastiana +2 more
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Mediators of Inflammation, 2009 Recent evidence shows that the renin-angiotensin system is a crucial player in atherosclerotic processes. The regulation of arterial blood pressure was considered from its first description of the main mechanism involved.
Fabrizio Montecucco +2 more
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