Results 11 to 20 of about 259,118 (384)

Network and 16S rRNA Sequencing-Combined Approach Provides Insightal Evidence of Vitamin K2 for Salt-Sensitive Hypertension

Frontiers in Nutrition, 2021
Vitamin K2 (VK2), found to act to treat hypertension, has been widely used in the food and pharmaceutical industries nowadays. However, the potential targets and molecular mechanisms of VK2 for salt-sensitive hypertension have not been fully investigated.
Tian-hao Liu, Ming-hao Chen, Wan-qing Tu, Qiu-er Liang, Wen-cong Tao, Zhen Jin, Ya Xiao, Li-guo Chen   +7 more
doaj   +1 more source

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

Circulation Research, 2020
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory ...
Mahmoud Gheblawi, Kaiming Wang, A. Viveiros, Quynh Nguyen, J. Zhong, A. Turner, M. Raizada, M. Grant, G. Oudit   +8 more
semanticscholar   +1 more source

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

New England Journal of Medicine, 2020
RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain.
M. Vaduganathan, O. Vardeny, T. Michel, J. McMurray, M. Pfeffer, S. Solomon   +5 more
semanticscholar   +1 more source

Myocardial and Renal Renin-Angiotensin System Enzyme Activity in Dogs. [PDF]

J Vet Intern Med
Weitzhandler EC, Ames MK, Wilson MD, Domenig O.   +3 more
europepmc   +3 more sources

Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension

Emerging Microbes and Infections, 2020
The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor blockers
J. Meng, Guohui Xiao, Juanjuan Zhang, Xing He, M. Ou, Jing Bi, Rongqing Yang, Wencheng Di, Zhaoqin Wang, Zigang Li, Hong-yu Gao, Lei Liu, Guoliang Zhang   +12 more
semanticscholar   +1 more source

Renin‐angiotensin system revisited [PDF]

Journal of Internal Medicine, 2008
Abstract.New components and functions of the renin‐angiotensin system (RAS) are still being unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin, acting on angiotensinogen to produce angiotensin I, which in turn was converted into angiotensin II (Ang II) by angiotensin‐converting enzyme (ACE).
F, Fyhrquist, O, Saijonmaa
openaire   +2 more sources

Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19

Cardiovascular Research, 2020
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of mortality worldwide, and its importance is further emphasized in the context of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
R. Kreutz, E. Algharably, M. Azizi, P. Dobrowolski, T. Guzik, A. Januszewicz, A. Persu, A. Prejbisz, T. Riemer, Ji-Guang Wang, M. Burnier   +10 more
semanticscholar   +1 more source

Renin-Angiotensin System [PDF]

New England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +3 more sources

What’s new in the renin-angiotensin system?

Cellular and Molecular Life Sciences (CMLS), 2004
.Cellular entry of enveloped viruses is often dependent on attachment proteins expressed on the host cell surface. Viral envelope proteins bind these receptors, and, in an incompletely understood process, facilitate fusion of the cellular and viral ...
Wenhui Li, M. J. Moore, N. Vasilieva, J. Sui, S. Wong, M. Berne, M. Somasundaran, J. Sullivan, K. Luzuriaga, T. Greenough, H. Choe, M. Farzan   +11 more
semanticscholar   +1 more source

Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic

Nature Reviews Nephrology, 2020
The current COVID-19 pandemic is associated with unprecedented morbidity and mortality. Early reports suggested an association between disease severity and hypertension but did not account for sources of confounding. However, the responsible virus — SARS-
A. South, L. Tomlinson, Daniel L. Edmonston, S. Hiremath, M. Sparks   +4 more
semanticscholar   +1 more source