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Alternative Renin-Angiotensin System. [PDF]
HypertensionThe renin-angiotensin system is the most important peptide hormone system in the regulation of cardiovascular homeostasis. Its classical arm consists of the enzymes, renin, and angiotensin-converting enzyme, generating angiotensin II from angiotensinogen, which activates its AT 1 receptor, thereby increasing blood ...
Bader M +4 more
europepmc +4 more sources
Renin Angiotensin System and Covid-19 Infection [PDF]
Advanced Pharmaceutical Bulletin, 2022 Purpose The new coronavirus, called SARS-CoV-2, is responsible for the recent global pandemic COVID-19. The status of the global pandemic COVID-19 is currently underway, and the virus has caused about 1.11 million deaths.
Francesco Ferrara, Antonio Vitiello
doaj +1 more source
Renin-Angiotensin System [PDF]
Archives of Andrology, 1988 Renin, a protease that cleaves the prohormone angiotensinogen thereby releasing angiotensin I, plays a major role in regulating blood pressure and electrolyte balance. Although renin is synthesized mainly in the cortical cells of the kidney, the presence of renin or reninlike activity has been recognized in various extrarenal tissues of humans and ...
Norio Nonomura +4 more
openaire +2 more sources
Regulatory effect of gut microbes on blood pressure
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 513-531, December 2022., 2022 The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan +6 more
wiley +1 more source
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
Circulation Research, 2020 ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory ...
Mahmoud Gheblawi +8 more
semanticscholar +1 more source
Frontiers in Nutrition, 2021 Vitamin K2 (VK2), found to act to treat hypertension, has been widely used in the food and pharmaceutical industries nowadays. However, the potential targets and molecular mechanisms of VK2 for salt-sensitive hypertension have not been fully investigated.
Tian-hao Liu +7 more
doaj +1 more source
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
New England Journal of Medicine, 2020 RAAS Inhibitors in Patients with Covid-19 The effects of renin–angiotensin–aldosterone system blockers on angiotensin-converting enzyme 2 levels and activity in humans are uncertain.
M. Vaduganathan +5 more
semanticscholar +1 more source
Incretin-based therapies and renin-angiotensin system: Looking for new therapeutic potentials in the diabetic milieu [PDF]
, 2020 Incretin-based therapies include pharmacologic agents such as glucagon like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors which exert potent anti-hyperglycemic effects in the diabetic milieu.
Jamialahmadi, Tannaz +4 more
core +1 more source
Emerging Microbes and Infections, 2020 The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor blockers
J. Meng +12 more
semanticscholar +1 more source
Intrarenal renin–angiotensin system [PDF]
Molecular and Cellular Endocrinology, 2009 Phylogenetically the renin-angiotensin system (RAS) is an ancient regulatory system which has attracted the attention of researchers for about a century. As a result of their efforts, different types of RAS inhibitors are now widely used as therapeutic medicines. The scientific enthusiasm toward RAS remains undiminished and new findings and discoveries
László Rosivall, László Rosivall
openaire +5 more sources