Results 201 to 210 of about 172,424 (309)

Adipocyte renin-angiotensin system signaling in periaortic fat: Neutral findings with mechanistic implications. [PDF]

JVS Vasc Sci
Wang B.
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Obesity exacerbates experimental colitis due to the activation of the local renin-angiotensin system in the colon. [PDF]

Sci Rep
Pan M, Xu Q, Huang L, Bai Y, Li X, Tang Y.   +5 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Role of Renin-Angiotensin System and Macrophages in Breast Cancer Microenvironment. [PDF]

Diseases
Alamro AA, Almutlaq MA, Alghamdi AA, Alshammari AH, Alshehri E, Abdi S.   +5 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Renin-angiotensin system blockade attenuates brain mitochondrial dysfunction, oxidative stress, and neuroinflammation associated with hypertension, metabolic disorders, and aging. [PDF]

World J Exp Med
García Menéndez S, Inserra F, de Cavanagh EM, Ferder L, Manucha W.   +4 more
europepmc   +1 more source

Renin–angiotensin systems and reproduction

Gynecological Endocrinology, 1999
G P, Vinson, E, Saridogan, J R, Puddefoot, O A, O'Mahony, T, Mahmood, O, Djahanbakhch   +5 more
openaire   +2 more sources

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Modulation of the Renin-Angiotensin System in Critically Ill Patients: Addressing Seven Key Questions for the Intensivist. [PDF]

Anesthesiology
Calabrese A, Bianchi V, Picod A, Bignami EG, Vincent JL, Taccone FS, Annoni F.   +6 more
europepmc   +1 more source