Results 211 to 220 of about 18,284,607 (258)
Some of the next articles are maybe not open access.
Annual Review of Physiology, 1978
Since the discovery of renin 80 years ago, there have been remarkable advances in our understanding of the renin-angiotensin system. The system as it is known today is summarized in Figure 1. Angiotensin III, the active component of the system, has several important physiological actions.
I A, Reid, B J, Morris, W F, Ganong
openaire +2 more sources
Since the discovery of renin 80 years ago, there have been remarkable advances in our understanding of the renin-angiotensin system. The system as it is known today is summarized in Figure 1. Angiotensin III, the active component of the system, has several important physiological actions.
I A, Reid, B J, Morris, W F, Ganong
openaire +2 more sources
Pharmacological Reviews, 1965
The major actions of this system seem to be exerted at an extracellular level even though there are strong suggestions that some intracellular effects may also be important.
openaire +2 more sources
The major actions of this system seem to be exerted at an extracellular level even though there are strong suggestions that some intracellular effects may also be important.
openaire +2 more sources
The Ontogeny of the Renin-Angiotensin System
Clinics in Perinatology, 1981This article reviews the seven components of the renin-angiotensin system —renin, renin substrate, angiotensin I, converting enzyme, angiotensin II, angiotensin III, and angiotensinases — and emphasizes current knowledge of this system during development.
J C, Pelayo, G M, Eisner, P A, Jose
openaire +2 more sources
Medical Clinics of North America, 1987
The renin-angiotensin systems are important regulators of cardiovascular homeostasis and participate in a variety of pathological conditions. Recent advances have not only clarified the functioning of the systemic renin cascade but have also indicated the importance of the generation of angiotensin in tissues.
openaire +2 more sources
The renin-angiotensin systems are important regulators of cardiovascular homeostasis and participate in a variety of pathological conditions. Recent advances have not only clarified the functioning of the systemic renin cascade but have also indicated the importance of the generation of angiotensin in tissues.
openaire +2 more sources
C. The renin-angiotensin system. A history and review of the renin-angiotensin system
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1969Abstract An outline of the development of knowledge of the renin-angiotensin system is given, and the nature of the enzyme renin, its site within the kidney as well as in other organs, and its action on plasma substrate to form first the decapeptide which is converted to the biologically active octapeptide, are considered. The methods
openaire +2 more sources
Reproduction and the renin-angiotensin system
Neuroscience & Biobehavioral Reviews, 1995A unique aspect of the circulating renin-angiotensin system and the many independent tissue renin-angiotensin systems is their interactions at multiple levels with reproduction. These interactions, which have received relatively little attention, include effects of estrogens and possibly androgens on hepatic and renal angiotensinogen mRNA; effects of ...
openaire +2 more sources
The Pulmonary Renin-Angiotensin System
Current Pharmaceutical Design, 2003The circulating renin-angiotensin system (RAS) has a well-described role in circulatory homeostasis. Recently, local tissue-based RAS have also been described which appear to play a key role in the injury/repair response. The expression of RAS components and the elevation of angiotensin converting enzyme in a number of interstitial lung diseases ...
openaire +2 more sources
Renin angiotensin system and ASCVD
Current Opinion in Cardiology, 2000The renin angiotensin system was first described over 100 years ago and is still the focus of intense clinical and basic science investigation. The renin angiotensin system was demonstrated to play a major pathogenetic role in hypertension. The development of inhibitors of angiotensin-converting enzyme and specific receptor blockers for angiotensin-II ...
openaire +2 more sources
The CNS renin-angiotensin system
Cell and Tissue Research, 2006The renin-angiotensin system (RAS) is one of the best-studied enzyme-neuropeptide systems in the brain and can serve as a model for the action of peptides on neuronal function in general. It is now well established that the brain has its own intrinsic RAS with all its components present in the central nervous system.
O, von Bohlen und Halbach, D, Albrecht
openaire +2 more sources
Renin-Angiotensin System in Sepsis
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987The time course of the components of the renin-angiotensin system was investigated in the plasma of three patients on the intensive care unit. Two of them, which were both polytraumatized, suffered from adult respiratory distress syndrome (ARDS). All patients had sepsis and impaired pulmonary and renal function.
U, Hilgenfeldt +4 more
openaire +2 more sources