Results 21 to 30 of about 928,186 (425)

Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19

Cardiovascular Research, 2020
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of mortality worldwide, and its importance is further emphasized in the context of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
R. Kreutz, E. Algharably, M. Azizi, P. Dobrowolski, T. Guzik, A. Januszewicz, A. Persu, A. Prejbisz, T. Riemer, Ji-Guang Wang, M. Burnier   +10 more
semanticscholar   +1 more source

Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19

New England Journal of Medicine, 2020
Background There is concern about the potential of an increased risk related to medications that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus disease 2019 (Covid-19), because the viral receptor is angiotensin ...
H. Reynolds, S. Adhikari, C. Pulgarin, A. Troxel, E. Iturrate, Stephen B. Johnson, A. Hausvater, J. Newman, J. Berger, S. Bangalore, S. Katz, G. Fishman, Dennis Kunichoff, Yu Chen, G. Ogedegbe, J. Hochman   +15 more
semanticscholar   +1 more source

The intracrine renin–angiotensin system [PDF]

Clinical Science, 2012
The RAS (renin–angiotensin system) is one of the earliest and most extensively studied hormonal systems. The RAS is an atypical hormonal system in several ways. The major bioactive peptide of the system, AngII (angiotensin II), is neither synthesized in nor targets one specific organ.
Kumar, R., Thomas, C.M.G., Yong, Q.C., Chen, W., Baker, K.M.   +4 more
openaire   +4 more sources

Renin-Angiotensin System Blockers and the COVID-19 Pandemic

HYPERTENSION, 2020
During the spread of the severe acute respiratory syndrome coronavirus-2, some reports of data still emerging and in need of full analysis indicate that certain groups of patients are at risk of COVID-19.
A. Danser, M. Epstein, D. Batlle
semanticscholar   +1 more source

Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal‐weight patients

Clinical Cardiology, Volume 45, Issue 12, Page 1236-1245, December 2022., 2022
Long‐term survival stratified for weight classes illustrated by Hazard plot for patients treated with MitraClip® implantation stratified for weight classes. Association of weight class compared to normal‐weight with long‐term survival (adjusted for Logistic EuroScore).
Karsten Keller, Martin Geyer, Lukas Hobohm, Alexander R. Tamm, Felix Kreidel, Tobias F. Ruf, Michaela Hell, Volker H. Schmitt, Kevin Bachmann, Sonja Born, Eberhard Schulz, Thomas Münzel, Ralph S. von Bardeleben   +12 more
wiley   +1 more source

Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19

New England Journal of Medicine, 2020
Background A potential association between the use of angiotensin-receptor blockers (ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus disease 2019 (Covid-19) has not been well studied.
G. Mancia, F. Rea, M. Ludergnani, G. Apolone, G. Corrao   +4 more
semanticscholar   +1 more source

A remote hypertension management program clinical algorithm

Clinical Cardiology, Volume 45, Issue 12, Page 1147-1162, December 2022., 2022
Abstract Introduction Hypertension is the leading risk factor for death, affecting over one billion people worldwide, yet control rates are poor and stagnant. We developed a remote hypertension management program that leverages digitally transmitted home blood pressure (BP) measurements, algorithmic care pathways, and patient–navigator communications ...
Hunter Nichols, Christopher P. Cannon, Benjamin M. Scirica, Naomi D. L. Fisher   +3 more
wiley   +1 more source

Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic

Nature Reviews Nephrology, 2020
The current COVID-19 pandemic is associated with unprecedented morbidity and mortality. Early reports suggested an association between disease severity and hypertension but did not account for sources of confounding. However, the responsible virus — SARS-
A. South, L. Tomlinson, Daniel L. Edmonston, S. Hiremath, M. Sparks   +4 more
semanticscholar   +1 more source

Prevalence, clinical characteristics, and predictors of sleep disordered breathing in hospitalized heart failure patients

Clinical Cardiology, Volume 45, Issue 12, Page 1311-1318, December 2022., 2022
Abstract Background Heart failure (HF) is often comorbid with sleep disordered breathing (SDB). This prospective study investigated the prevalence, clinical characteristics, and predictors of SDB in hospitalized HF patients. Methods Sleep studies were performed on hospitalized HF patients from January 2015 to February 2019.
Boping Huang, Yan Huang, Mei Zhai, Qiong Zhou, Shiming Ji, Huihui Liu, Xiaofeng Zhuang, Yuhui Zhang, Jian Zhang   +8 more
wiley   +1 more source

Renin-Angiotensin System [PDF]

New England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +5 more sources