Results 21 to 30 of about 205,704 (259)
Structurally Mapping Antibody Repertoires [PDF]
Frontiers in Immunology, 2018 Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity via next-generation sequencing of immunoglobulin genes (Ig-seq). This technique produces large volume sequence snapshots of B-cell receptors that are indicative of the antibody repertoire. In this paper, we enrich these large-scale sequence datasets with
Konrad Krawczyk +16 more
openaire +3 more sources
Stimulation-induced cytokine polyfunctionality as a dynamic concept
eLifeCytokine polyfunctionality is a well-established concept in immune cells, especially T cells, and their ability to concurrently produce multiple cytokines has been associated with better immunological disease control and subsequent effectiveness during ...
Kevin Portmann, Aline Linder, Klaus Eyer
doaj +1 more source
Frontiers in Immunology, 2014 B-1a cells constitutively secrete natural antibody that provides immediate protection against microbial pathogens and functions homeostatically to speed removal of apoptotic cell debris.
Nichol E Holodick +2 more
doaj +1 more source
The Current State of Bashkir Song Folklore: A Case Study of 21st-Century Expeditional Materials
Oriental Studies, 2021 Introduction. At present, people’s interest in the historical and ethnocultural heritage has increased, and the desire to preserve traditional values for future generations has grown stronger.
Aigul M. Khakimyanova
doaj +1 more source
The Human IgE Repertoire [PDF]
International Archives of Allergy and Immunology, 2013 IgE is a key mediator in allergic diseases. However, in strong contrast to other antibody isotypes, many details of the composition of the human IgE repertoire are poorly defined. The low levels of human IgE in the circulation and the rarity of IgE-producing B cells are important reasons for this lack of knowledge.
Gadermaier, Elisabeth +3 more
openaire +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Frontiers in Immunology, 2014 Chronic gastritis is characterized by gastric mucosal inflammation due to autoimmune responses or infection, frequently with Helicobacter pylori. Gastritis with H.
Miri eMichaeli +10 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Вестник музыкальной науки, 2014 Статья отражает опыт выстраивания репертуарной политики Хорового консорта ЛАБОРАТОРИИ НОВОЙ МУЗЫКИ Новосибирской консерватории, концертная деятельность которого осуществляется в рамках Международного фестиваля современной музыки «Сибирские сезоны ...
Рудзей, Е. В. +1 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source