Results 21 to 30 of about 705,796 (337)

Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing. [PDF]

open access: yes, 2019
Studying immune repertoire in the context of organ transplant provides important information on how adaptive immunity may contribute and modulate graft rejection. Here we characterize the peripheral blood immune repertoire of individuals before and after
Liberto, Juliane M   +5 more
core   +3 more sources

Repertoire-dependent immunopathology [PDF]

open access: yesJournal of Autoimmunity, 2007
In humans, limited T-cell receptor repertoire and lymphopenia are associated with severe eosinophilic inflammatory disease. A model of lymphopenia and reduced T-cell repertoire was created; C57BL/6 Rag2-/- mice received limited (30,000) or large (2 million) numbers of CD4 T-cells.
Andrea Keane-Myers   +4 more
openaire   +3 more sources

Immunoglobulin gene repertoire diversification and selection in the stomach – from gastritis to gastric lymphomas

open access: yesFrontiers in Immunology, 2014
Chronic gastritis is characterized by gastric mucosal inflammation due to autoimmune responses or infection, frequently with Helicobacter pylori. Gastritis with H.
Miri eMichaeli   +10 more
doaj   +1 more source

Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies

open access: yesFrontiers in Immunology, 2018
Therapeutic molecules derived from antibodies have become a dominant class of drugs used to treat human disease. Increasingly, therapeutic antibodies are discovered using transgenic animal systems that have been engineered to express human antibodies ...
Weihsu C. Chen, Christopher M. Murawsky
doaj   +1 more source

Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds [PDF]

open access: yes, 2017
How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study,
Barrett, R S   +10 more
core   +1 more source

Shaping the T cell repertoire. [PDF]

open access: yesThe Journal of Immunology, 2005
Today immunologists are well aware of positive and negative selection of developing T cells. This was very different almost three decades ago when MHC-restricted Ag recognition by T cells represented an enormous puzzle in the absence of data on the molecular nature of Ag recognition by T cells ...
openaire   +6 more sources

Epigenetic Enhancer Marks and Transcription Factor Binding Influence Vκ Gene Rearrangement in Pre-B Cells and Pro-B Cells

open access: yesFrontiers in Immunology, 2018
To date there has not been a study directly comparing relative Igκ rearrangement frequencies obtained from genomic DNA (gDNA) and cDNA and since each approach has potential biases, this is an important issue to clarify.
Eden Kleiman   +2 more
doaj   +1 more source

Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]

open access: yes, 2020
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi   +13 more
core  

Good-enough principles for welfare [PDF]

open access: yes, 1999
The aim of this article is to widen the grounds of the debate on the relationship between values, social change and welfare reform. In the public debate on welfare reform and the Third Way the significance of the welfare politics and campaigns of civil ...
Williams, F.
core   +1 more source

Развитие репертуара для кларнета (перевод)

open access: yesВестник музыкальной науки, 2018
Материал представляет собой перевод на русский язык статьи «Развитие репертуара для кларнета» британского исполнителя, преподавателя игры на кларнете, библиотекаря Общества кларнета и саксофона Великобритании Дж. Рис-Девис.
Аунс, Маргарита Владимировна
doaj   +1 more source

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